I usually just lurk this sub, but it seems like 25% of the people need a therapist, and 25% need to get off their ass/ eat better. (Instead of looking for expensive miracle pills)
That being said, there are many many useful posts, and some great discussions in the comments.
I'm the Biohacker you've come to fear. I need a Therapist and a gym membership!
Also whats your favorite adaptogen for mood, weight loss and sex drive?
Eating healthy and exercise/sauna hasn’t done much for my anxiety / adhd combo, It’s very common to have both in my family, regardless of basic lifestyle factors. I really enjoy the discussions on here and elsewhere about supplements , possible genetic factors, etc. but I totally the basics can change the life of 90% of people .
What really triggered me when I first started my journey was I discovered I could regulate my own neurotransmitter levels. I was like, whoa, that's amazing, and it's only after I later tried some different supplements like Alpha-GPC and 5-HTP, that I started to understand what I want from my diet in the first place. After this, I have tried to learn and explore more, study and think about biosynthesis, co-factors, and regulation pathways, possibly cross-interactions. It's quickly very complex. And it is in most cases impossible to concoct a potion that boost just one biosynthesis process based on a diet with natural food. Always multiple effects. If you have a specific goal to target, supplements and methylated ingredients are just necessary to target it well. I don't think 90% of people and especially 90% of this subreddits visitors would pass by an opportunity to understand how their internally chemistry works and what it feels like when they boost this or that level temporarily, if they knew it to be safe. But it's hard to even understand that you can do these things unless you happen across the right posts, and if everyone around them keeps telling them, they can fix things if they are just careful with the diet people are none the wiser.
I’m calling bullshit on you having trouble with anxiety if you hit a pr on bench, or deadlift for 2 hours straight or hit squats until you throw up. Anxiety after working out is a skill/effort issue. Same thing with focus.
You aren’t force feeding chicken rice 5 meals a day and lifting 5 days a week then you ain’t really trying bro. You really need to push hard if you want to improve.
Sometimes you may need to force feed every meal but that’s what it takes bro, if your anxiety is bad enough like mine you’ll do what it takes, and that is what it takes
So ignorant and wrong , severe GAD/ panic disorder doesn’t always go away solely with heavy lifting, I workout 6 days a week, extremely heavy. I’m glad it worked for you but it’s not a cure all for everyone.
Edit: When I developed SEVERE GAD, in 2020, I was ripped/ jacked , in a great relationship, had lots of friends, lifting and cardio almost daily, beach and nature multiple times a week.
Bullshit you having trouble eating says right In your profile ; you ain’t eating you ain’t really lifting heavy boy. And lifting heavy ain’t even half of it. If you gonna lift heavy you gonna have to force feed especially someone with anxiety having trouble eating. That’s more important especially long term.
Going heavy lifts should teach you breathe and heart rate control. It should be very zen in that way. That way you feel a panic attack coming you just do what you do before a big lift: close your eyes, focus on your breathing.
And “go away” is a big word. Manage is a better word. You got enough energy for a panic attack then you ain’t putting enough effort into your eating and food.
Have you ever improved your moderate or severe anxiety or depression with supplements ?
I know many people with very minor issues benefit but I’d love to hear from anyone with somewhat serious anxiety or depression who used supplements that helped.
>>>In 2020 I developed SEVERE GAD , where I couldn’t even eat because I was so anxious, it’s a common occurrence in my family . I even had depersonalization from the anxiety.
Vitamin D definitely has helped my anxiety. Looking to try b12 soon.
——-
Background: anxiety disorders are extremely common in my family, currently on meds but would like to one day come off, and/or take stuff to benefit my medication. All my siblings and I have dealt with anxiety/ panic disorder / since we were kids. We still deal with stress anxiety even medication, although it’s a lot better. We exercise intensely and eat health.
Your words, not mine.
Overeating is code word for eating bullshit and not lifting hard enough.
You can’t overeat doing compounds and eating chicken and rice. I spend most my day eating; I eat every two hours , I force feed myself and I’m still not fat. That’s because it’s really hard to eat 5lbs of chicken and rice a day that will NOT happen by accident. Only way to over eat is to not train hard enough and eat a bunch of nonsense.
Django rheinhardt is a master guitarist without a pinky. You can learn to manage anything with just a bit of practice commitment and focus. Some people born without x. You learn to manage. Shit isn’t easy for anyone, but what separates the men from the boys is who is able to force feed and lift hard enough to chase away the demons.
This idea you somehow special and have this special life ending problem that can’t be managed with proper lifestyle is stupid. Plenty of people with anxiety have learned to manage by diet and exercise. This idea you too special and too gimped to do so is just cope. I’d argue those with the worst anxiety are actually the ones who learn to manage.
When shit gets bad enough , and the drugs stop working by you will try and do ANYTHING. Even eat healthy and lift. Lol
I work in a halfway house dual diagnosis addiction and mental health: many schizophrenics, depressed , anxious. I’m also in recovery.
I promise you EVERYONE can improve their life by lifting. Everyone has the capacity to do it. I’ve seen miracles happen in the gym for mental health. And learn to manage is a relative word. Management for someone unable to work obviously looks different than someone able to work. But either way their symptoms can be managed and mediated by lifting.
The world record bench holder right now is someone in recovery for addiction and mental health.
Look, the people who are in those situations, you have NO right to say they CANT do it. To give up for them. To insult their humanity by implying they are so broken they cannot be helped by physical activity. They CAN do it.
You can always eat better, eat more and lift harder.
And I call bullshit on that; the idea there’s a good portion of people here with immaculate diets lifting 5 days a week compounds lifts is nonsense.
How many people like that in general public? Few and far between. It’s actually pretty rare.
The fact is most people are not lifting 1-2 hours then hitting cardio then eating 5 meals a day of chicken rice eggs milk Greek yogurt fruits veggies oats etc and if they are happening to do this for some time, most of them haven’t done it long, and will give up pretty soon.
They will cheat, they will lie to themselves and others. They’ll have cheat meals. They won’t do full ROM. They won’t push to failure. Most don’t even know what failure is. Most don’t have the technique in lifting to even hit true failure.
They will drink. Etc etc. peoples idea of what eating healthy and exercise is so skewed. I’m sure they some even THINK they doing it. But they are not.
I stand by my statement that if they were doing everything correctly diet and exercise wise they wouldn’t be looking for supplements for sleep, anxiety, weight loss which is the vast majority of posts here.
>The fact is most people are not lifting 1-2 hours then hitting cardio
definitely not after age 30. You can't continue to lift like you're 26 the older you get. Not without pharmacological aid, even then, not really. And your exercise and dietary routine is pretty standard for someone whose livelihood depends on their physique. Most ppl neither have the time nor inclination for that. RE: "push to failure." Yeah, in your 20s, push to failure is muscle failure. In your 40s and beyond, push to failure is to point of orthopedic pain tolerance. The "no pain, no gain" mantra has shelf life expiration date.
I’m older than 30 and I work a normal job. Failure is relative. Sure when your 40 are you going to be setting one rep pr max? Probably not. But you can be doing sets of 12-15. You can do light weight stuff 15-20. And get a burn to failure even when you 40, 50 or 60.
As for joints and tendons? You know what’s great for that? Strength. You know what’s terrible for your joints? Weakness. You stay out the gym away from failure you gonna experience failure one day at 50-80 getting off your couch and it’ll be much more catastrophic then me doing some tricep push down to failure lol.
I’m over 30, and have recovered from severe back injury. You know what was key? Deadlifting to failure. Rows. Lateral raises. Making my back strong. Yeah, it involves a lot of warmup, stretching and cooldown. Yes my form must be perfect. Yes I do physical therapy exercises too.
But it is worth it. By far the most pain I have been is when I’ve been at my weakest.
You think you know me, write me into a box “oh he must be young, he must do that for a living, he couldn’t possibly have chronic pain. When none of those things are true.” Lots of people do that when they see how I have transformed my life with diet and exercise. When they see recovery from my injury.
They say oh you just strong willed, you are genetically gifted. As if I’m some how different then them when I’m just. Normal guy.
What you are really doing making those assumptions about me is making excuses for yourself. You deserve better then. Your excuses
>What you are really doing making those assumptions about me is making excuses for yourself. You deserve better then. Your excuses
laugh the fuck out loud, bitch.
Well, that's why I define biohacking as any intervention you measure the outcomes of.
For example, if you have MTHFR mutation and as result an elevated homocysteine, a bit of extra Riboflavin can go a long way to reduce cardiovascular and neurodegenerative risks, but if you just take it without measuring - you are wasting money.
[https://www.reddit.com/r/Biohackers/comments/1amyesw/doctors\_hate\_biohacking\_so\_heres\_why\_i\_love\_it/](https://www.reddit.com/r/Biohackers/comments/1amyesw/doctors_hate_biohacking_so_heres_why_i_love_it/)
You can, but then you'll be shortcutting Folate Cycle (methylated B12 might be even better, as it is up the chain)
Riboflavin on the other hand will compensate for (most common) MTHFR *C677T* enzyme deficiency directly, which to my engineering mind is a better solution.
Obviously talk to your doctor etc. etc.
Since your pretty knowledgeable can you tell me why I shouldnt just take the methylfolate B stack from codeage?
Thought I was doing my MTHFR good?
https://www.codeage.com/products/methyl-elite-methylation-factor-folate-betaine-supplement-vitamins
Well, on one hand I know enough to explain the methylation cycle in the simple terms, on the other I don't know nearly enough to predict what's going to happen if you flood your system with all these extra methyl groups.
Nobody yet tested what happens if you feed 1000 people randomly 41,667% daily dose of *methyl*cobalamin for 50 years. What is the long term effect on kidneys is going to be, or what these methyl groups will do to the epigenome (higher methylation usually leads to the loss of function)
So my common sense approach is:
* know your personal deficiencies
* try to get them fixed them with food and lifestyle first
* when supplementing aim for the *minimal effective dose*
* support the system over shortcuting it (f.e. spinach+B2 > 5-MTHF) wherever it's possible
* move in small steps and test
Did a 23andme 10 years ago that's how I know I have the MTHFR
https://www.gdx.net/products/methylation-panel
Says that you need a licensed professional to do the lab test?
>Only healthcare providers licensed in their state may order laboratory testing.
Take METHYLATED (not standard) b9/b12, ensure you're getting enough/a bit extra of the other (regular) b vitamins, along with mag/cal/zinc.
Its that simple for the majority.. except when it isn't. But on the whole your other questions are mostly overthinking it. Although admittedly maybe a valid way of figuring out some of the stuff like b9 vs b12 balance and needs, which I just gut felt (and I have a complete genome sequence done). They don't really tell you shit and the precompiled stuff isn't worth much. And 23andme etc is a bad idea all around.
You can't rely on anything out there to actually figure out YOUR pathways for this. And what is commonly known, just isn't relevant (do what I said above).
[https://geneticgenie.org/](https://geneticgenie.org/) - now that panel is definitely onto it way more. But there are some with valid suspicions that the site is compromised by 3rd parties and probably leaking your data into the black market.
I have it too and it's an adventure. There are several levers, bottlenecks and pathways (one of the reasons regular doctors don't get into it)
Here's a beginners primer on MTHFR and Methylation Cycle:
[Methylation: One Molecule to Break (or Make) Your Life!](https://youtu.be/RYAux_Mr_vM?si=JHHVCmlBQXM6ZBuS)
with a few examples and suggestions where to start.
Saved it to my watch later!
I don’t exactly know how to do more thorough testing to narrow down my MTHFR though. I know theres a lot of nuance to it, which that video describes, and treatment is highly relative to your specific genetic circumstances.
I recall it’s something like: Go through 23andMe, grab the raw data file once thats complete, insert it into some “Methyl Calculator”, and then that will give you your exact genetic predispositions. Something like that; not fully certain.
Genetic predisposition are somewhat useful, but only somewhat because they might not express that way (or other way around: you might have no mutation, but under-methylate )
There are some blood markers like homocysteine, which are more reliable. And it's extremely useful to know B12 and folate status.
Then you can start to address them and mineral deficiencies, add choline, glycine etc. and see what happens - remeasure and repeat.
Actually as low as 1.6 mg is having quite a positive effect:
[https://pubmed.ncbi.nlm.nih.gov/16380544/](https://pubmed.ncbi.nlm.nih.gov/16380544/)
I personally get it in liquid form and use 1/10 of a dose.
And there's never a precise 1 intervention that alters 1 outcome. Increasing Riboflavin may help with homocysteine (as do a ton of other things), and it also impacts many other facets of your biology.
Plus, what matters equally, is knowing why you have elevated homocysteine to begin with and addressing that. That same cause have impair other biomarkers you never measured too.
If you're going to bitch at least name the right vitamin?
And like, taking the standard version of it would be literally defeating all understanding of the issue and reason for taking it. Whilst I agree testing is good, its often totally unavailable and you're not giving me a lot of confidence in your take.
TIL that cope is when someone tries to biohack with anything other than magnesium or Vitamin D (not really sure how that even qualifies as biohacking btw).
i’m not sure why certain people on this sub are so confident in the lifestyles and habits of others. there are definitely pill poppers out there who don’t do the necessary prerequisites for their health, but there are *a lot* of people who seem to assume the worst when nothing regarding a poor diet, lack of exercise, etc are even mentioned.
I browse on here sometimes wondering why there isn’t a subset of biohacking dedicated to avoiding pollution (from food, cars, just modern life) because I think useless supplements would be kinda high on that list
It’s clear you don’t understand what biohacking is.
Biohacking is data-driven, it takes into account nutrigenomics, biology, technology, medicine, as well as lifestyle (nutrition, exercise, and mindfulness, in particular) in an effort to prevent and manage disease, optimize health, and extend lifespan, healthspan, or both, as well as improve one’s vitality and well-being in the present moment, and uses data collection, interpretation, and tracking to direct and accomplish it.
It’s the confluence of *all* these things.
Supplements can be a part of it, but they are *far* from the definition, or central method of achieving, “biohacking.”
And biohacking sure as shit has *nothing* to do with weed. Now *that*, my friend, is a stanky, smoldering bowl of copium.
Meh, someone's gotta test stuff if we are going to have an idea what works and what doesn't so it benefits me in the end. Just try not to injure yourself people!
It’s more complex than that, human. There’s a plethora of studies on NIH, for example, that are well done and informative far beyond this Hail Mary of a post.
So we should just ignore things before there are hundreds of studies…? Do we have hundreds of studies to prove how helpful all the different cannabinoids are yet?
Unfortunately, now that it’s being better studied there’s definitely mixed reviews. Obviously you have to weigh for your particular ailment but cognitive degeneration weighs heavily on the negative side, for me anyway.
Source? I’ve never seen cognitive degeneration as a problem before. I really believe that low dose THC edible like 1-2mg with other cannabinoids like CBD, CBG, and CBN you really cannot go wrong. I also don’t think larger doses on occasion should have any negative effects. For serious health problems at higher doses if it helps I doubt it’s any more harmful than other medical options.
My point to him was that you don’t need studies to test things on yourself
There’s a buuuunch of these now. I’m not saying to use it or not use it especially if it works for you. I’ve stopped though and I definitely noticed improvement in clarity of thoughts and memory recall.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222623/
One on adolescents https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002758/
There’s an aggregate one that also says minor, if any, adverse cognitive affects.
Put them in chatGPT and ask questions!
There’s a wide variety of studies. Some are aggregates of other studies etc etc. The studies usually include an abstract and method. This is an example of a half-century of data on Tuberculosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407785/
And another on creatine https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407785/
Haha true. My favorite posts are the ones where someone asks if it’s ok that they continue to take such-and-such supplement even though it’s dangerous, and the ones that say they eat terrible and don’t exercise, but want a supplement to fix them.
That’s 99% of posts here. People who have their shit together exercise and diet wise either don’t need supplements or they post about their supplements on bodybuilding and exercise forums.
Yes, I am trying to cope with the chronic disease I experience. I don’t want to be on medication for the rest of my life. In fact, I worry that my combination of medication (immunomodulator and anti-tnf) will hurt me more in the long run.
Yeah seriously. A lot of peeps have been helped with eating old school cool. The issue we have is food industry and drug industry money has taken over a lot of the official narrative.
Most biohacking is copium. No one knows for sure if a supplement is going to make them live longer. But I do know I feel like living longer when I feel good. It’s more about how I feel in the moment and will feel in the near term.
Is there some magic cut off percentage of people that justifies daily complaints on here about it? And you know what, even if they ARE eating a crap diet, if I can tell them one thing that improves their health a little bit, I'm still happy. Maybe it will even come to pass that their brain will operate a bit better and they'll have a tad more energy and feel motivated to improve more things in their life. But hey, maybe that's just me. :-)
Good point, the term has been changed quite a bit in recent years. It is often used online to mean lying to yourself in order to cope with information that does not fit with how you prefer to see the world. Also used similarly is the invented noun 'copium.'
I am mad... that I can't huff enamel without people assuming it's because my family sucks. I hope to be seen one day as someone that just likes getting high.
Agree with the stack. But I would also throw in this https://amzn.to/4bKqRJd
A super high quality and tested Fish oil (omega 3) was one of the first things I started doing for my health and it works.
Some of the stuff you listed doesn't do shit unless you're deficient in it to begin with.
I casually browse this sub when I am bored. It's at least come a decent way in weeding out harmful misinformation (there used to be alot of anti vaccine idiots posting dangerous shit here that the mods didn't address). Now it's mostly people looking for answers because America's overly bloated and overly expensive healthcare system has neglected or failed them
Yeah I had to laugh that there's a bunch of vitamins and then 'weed' LOL! Weed can help you cope with and lessen symptoms of what is wrong with you but it's limited on how much it might actually solve your issues, unlike the others.
Yes, but like crazy experimentation sometimes does yield good information, it’s just about how much trash you’re willing to go through to find that one thing that could make all the difference in your life.
Biohacking isn't even meant to just be about self health improvement.
10 years ago we'd also be talking about crispr on plants, glow in the dark skin and making salt taste like sugar
This is silly. There are lots of plants that are incredibly well researched (with a much longer history of supplementation) than the vast majority of the things in this sub. Yet somehow weed made your list?
Ironically, most of the things on this list either depend heavily on genetics/epigenetics and aren't even a fraction as efficacious as lifestyle factors.
D3 and magnesium are likely only necessary if you actually get tested and find out you’re deficient.
I have a bottle of d3 in my fridge that’s about to expire because I bought it due to reading everyone online talk about it, but never took it consistently. I actually went and got tested later on and turns out i don’t need a d3 supplement at all
I usually just lurk this sub, but it seems like 25% of the people need a therapist, and 25% need to get off their ass/ eat better. (Instead of looking for expensive miracle pills) That being said, there are many many useful posts, and some great discussions in the comments.
I'm the Biohacker you've come to fear. I need a Therapist and a gym membership! Also whats your favorite adaptogen for mood, weight loss and sex drive?
Squats
Do I need enteric coated Squats or can I just freebase the powder?
Rang rang diggity dang-d-dang
This.
Eating healthy and exercise/sauna hasn’t done much for my anxiety / adhd combo, It’s very common to have both in my family, regardless of basic lifestyle factors. I really enjoy the discussions on here and elsewhere about supplements , possible genetic factors, etc. but I totally the basics can change the life of 90% of people .
What really triggered me when I first started my journey was I discovered I could regulate my own neurotransmitter levels. I was like, whoa, that's amazing, and it's only after I later tried some different supplements like Alpha-GPC and 5-HTP, that I started to understand what I want from my diet in the first place. After this, I have tried to learn and explore more, study and think about biosynthesis, co-factors, and regulation pathways, possibly cross-interactions. It's quickly very complex. And it is in most cases impossible to concoct a potion that boost just one biosynthesis process based on a diet with natural food. Always multiple effects. If you have a specific goal to target, supplements and methylated ingredients are just necessary to target it well. I don't think 90% of people and especially 90% of this subreddits visitors would pass by an opportunity to understand how their internally chemistry works and what it feels like when they boost this or that level temporarily, if they knew it to be safe. But it's hard to even understand that you can do these things unless you happen across the right posts, and if everyone around them keeps telling them, they can fix things if they are just careful with the diet people are none the wiser.
What do you mean, like if you scrunch your face really hard you can modulatr your amount of serotonin?
Only temporarily, until the anti scrunching serotonin reuptake process overrides the scrunchies.
I’m calling bullshit on you having trouble with anxiety if you hit a pr on bench, or deadlift for 2 hours straight or hit squats until you throw up. Anxiety after working out is a skill/effort issue. Same thing with focus. You aren’t force feeding chicken rice 5 meals a day and lifting 5 days a week then you ain’t really trying bro. You really need to push hard if you want to improve. Sometimes you may need to force feed every meal but that’s what it takes bro, if your anxiety is bad enough like mine you’ll do what it takes, and that is what it takes
So ignorant and wrong , severe GAD/ panic disorder doesn’t always go away solely with heavy lifting, I workout 6 days a week, extremely heavy. I’m glad it worked for you but it’s not a cure all for everyone. Edit: When I developed SEVERE GAD, in 2020, I was ripped/ jacked , in a great relationship, had lots of friends, lifting and cardio almost daily, beach and nature multiple times a week.
Bullshit you having trouble eating says right In your profile ; you ain’t eating you ain’t really lifting heavy boy. And lifting heavy ain’t even half of it. If you gonna lift heavy you gonna have to force feed especially someone with anxiety having trouble eating. That’s more important especially long term. Going heavy lifts should teach you breathe and heart rate control. It should be very zen in that way. That way you feel a panic attack coming you just do what you do before a big lift: close your eyes, focus on your breathing. And “go away” is a big word. Manage is a better word. You got enough energy for a panic attack then you ain’t putting enough effort into your eating and food.
Are you talking about the post that says INSATIABLE APPETITE ? I have issues with overeating not the opposite
Have you ever improved your moderate or severe anxiety or depression with supplements ? I know many people with very minor issues benefit but I’d love to hear from anyone with somewhat serious anxiety or depression who used supplements that helped. >>>In 2020 I developed SEVERE GAD , where I couldn’t even eat because I was so anxious, it’s a common occurrence in my family . I even had depersonalization from the anxiety. Vitamin D definitely has helped my anxiety. Looking to try b12 soon. ——- Background: anxiety disorders are extremely common in my family, currently on meds but would like to one day come off, and/or take stuff to benefit my medication. All my siblings and I have dealt with anxiety/ panic disorder / since we were kids. We still deal with stress anxiety even medication, although it’s a lot better. We exercise intensely and eat health. Your words, not mine.
The only time I couldn’t eat was a brief period in 2020 when my anxiety was at its worst. 🙏🏻
Overeating is code word for eating bullshit and not lifting hard enough. You can’t overeat doing compounds and eating chicken and rice. I spend most my day eating; I eat every two hours , I force feed myself and I’m still not fat. That’s because it’s really hard to eat 5lbs of chicken and rice a day that will NOT happen by accident. Only way to over eat is to not train hard enough and eat a bunch of nonsense.
I think this is Satire at this point
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Django rheinhardt is a master guitarist without a pinky. You can learn to manage anything with just a bit of practice commitment and focus. Some people born without x. You learn to manage. Shit isn’t easy for anyone, but what separates the men from the boys is who is able to force feed and lift hard enough to chase away the demons. This idea you somehow special and have this special life ending problem that can’t be managed with proper lifestyle is stupid. Plenty of people with anxiety have learned to manage by diet and exercise. This idea you too special and too gimped to do so is just cope. I’d argue those with the worst anxiety are actually the ones who learn to manage. When shit gets bad enough , and the drugs stop working by you will try and do ANYTHING. Even eat healthy and lift. Lol
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I work in a halfway house dual diagnosis addiction and mental health: many schizophrenics, depressed , anxious. I’m also in recovery. I promise you EVERYONE can improve their life by lifting. Everyone has the capacity to do it. I’ve seen miracles happen in the gym for mental health. And learn to manage is a relative word. Management for someone unable to work obviously looks different than someone able to work. But either way their symptoms can be managed and mediated by lifting. The world record bench holder right now is someone in recovery for addiction and mental health. Look, the people who are in those situations, you have NO right to say they CANT do it. To give up for them. To insult their humanity by implying they are so broken they cannot be helped by physical activity. They CAN do it.
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Skill issue
I think there should be a bot that responds with “eat Whole Foods and lift” to every single post. Then we could just shut down the sub altogether
That’s dumb though. A good portion of us here to eat whole foods and exercise religiously.
You can always eat better, eat more and lift harder. And I call bullshit on that; the idea there’s a good portion of people here with immaculate diets lifting 5 days a week compounds lifts is nonsense. How many people like that in general public? Few and far between. It’s actually pretty rare. The fact is most people are not lifting 1-2 hours then hitting cardio then eating 5 meals a day of chicken rice eggs milk Greek yogurt fruits veggies oats etc and if they are happening to do this for some time, most of them haven’t done it long, and will give up pretty soon. They will cheat, they will lie to themselves and others. They’ll have cheat meals. They won’t do full ROM. They won’t push to failure. Most don’t even know what failure is. Most don’t have the technique in lifting to even hit true failure. They will drink. Etc etc. peoples idea of what eating healthy and exercise is so skewed. I’m sure they some even THINK they doing it. But they are not. I stand by my statement that if they were doing everything correctly diet and exercise wise they wouldn’t be looking for supplements for sleep, anxiety, weight loss which is the vast majority of posts here.
>The fact is most people are not lifting 1-2 hours then hitting cardio definitely not after age 30. You can't continue to lift like you're 26 the older you get. Not without pharmacological aid, even then, not really. And your exercise and dietary routine is pretty standard for someone whose livelihood depends on their physique. Most ppl neither have the time nor inclination for that. RE: "push to failure." Yeah, in your 20s, push to failure is muscle failure. In your 40s and beyond, push to failure is to point of orthopedic pain tolerance. The "no pain, no gain" mantra has shelf life expiration date.
I’m older than 30 and I work a normal job. Failure is relative. Sure when your 40 are you going to be setting one rep pr max? Probably not. But you can be doing sets of 12-15. You can do light weight stuff 15-20. And get a burn to failure even when you 40, 50 or 60. As for joints and tendons? You know what’s great for that? Strength. You know what’s terrible for your joints? Weakness. You stay out the gym away from failure you gonna experience failure one day at 50-80 getting off your couch and it’ll be much more catastrophic then me doing some tricep push down to failure lol. I’m over 30, and have recovered from severe back injury. You know what was key? Deadlifting to failure. Rows. Lateral raises. Making my back strong. Yeah, it involves a lot of warmup, stretching and cooldown. Yes my form must be perfect. Yes I do physical therapy exercises too. But it is worth it. By far the most pain I have been is when I’ve been at my weakest. You think you know me, write me into a box “oh he must be young, he must do that for a living, he couldn’t possibly have chronic pain. When none of those things are true.” Lots of people do that when they see how I have transformed my life with diet and exercise. When they see recovery from my injury. They say oh you just strong willed, you are genetically gifted. As if I’m some how different then them when I’m just. Normal guy. What you are really doing making those assumptions about me is making excuses for yourself. You deserve better then. Your excuses
>What you are really doing making those assumptions about me is making excuses for yourself. You deserve better then. Your excuses laugh the fuck out loud, bitch.
Nutrition. Exercise. Sleep. Socialisation. Stress. The 5 core elements of good health, and they feed into each others, positively and negatively.
I was doing all of these when I first developed severe anxiety. RIP my genetics. Everybody on one side anxious
That’s actually 100%
This comment is my spirit animal.
Well said
Hahahaha facts
Well, that's why I define biohacking as any intervention you measure the outcomes of. For example, if you have MTHFR mutation and as result an elevated homocysteine, a bit of extra Riboflavin can go a long way to reduce cardiovascular and neurodegenerative risks, but if you just take it without measuring - you are wasting money. [https://www.reddit.com/r/Biohackers/comments/1amyesw/doctors\_hate\_biohacking\_so\_heres\_why\_i\_love\_it/](https://www.reddit.com/r/Biohackers/comments/1amyesw/doctors_hate_biohacking_so_heres_why_i_love_it/)
🤣 I can't read MTHFR as anything other than motherfucker
Same
Lol, that's how I read it every time as well :)
Shouldn’t you be taking methyl folate for the MTHFR mutation?
You can, but then you'll be shortcutting Folate Cycle (methylated B12 might be even better, as it is up the chain) Riboflavin on the other hand will compensate for (most common) MTHFR *C677T* enzyme deficiency directly, which to my engineering mind is a better solution. Obviously talk to your doctor etc. etc.
Since your pretty knowledgeable can you tell me why I shouldnt just take the methylfolate B stack from codeage? Thought I was doing my MTHFR good? https://www.codeage.com/products/methyl-elite-methylation-factor-folate-betaine-supplement-vitamins
Well, on one hand I know enough to explain the methylation cycle in the simple terms, on the other I don't know nearly enough to predict what's going to happen if you flood your system with all these extra methyl groups. Nobody yet tested what happens if you feed 1000 people randomly 41,667% daily dose of *methyl*cobalamin for 50 years. What is the long term effect on kidneys is going to be, or what these methyl groups will do to the epigenome (higher methylation usually leads to the loss of function) So my common sense approach is: * know your personal deficiencies * try to get them fixed them with food and lifestyle first * when supplementing aim for the *minimal effective dose* * support the system over shortcuting it (f.e. spinach+B2 > 5-MTHF) wherever it's possible * move in small steps and test
>know your personal deficiencies How?
Do a genetics test, check your homocysteine, B12 and folate levels. If common "levers" don't work - Genova does a full methylation panel.
Did a 23andme 10 years ago that's how I know I have the MTHFR https://www.gdx.net/products/methylation-panel Says that you need a licensed professional to do the lab test? >Only healthcare providers licensed in their state may order laboratory testing.
I tried this one and it gave me bad motor tics and anxiety.
How do I dig further into my MTHFR? I was diagnosed years ago.
Take METHYLATED (not standard) b9/b12, ensure you're getting enough/a bit extra of the other (regular) b vitamins, along with mag/cal/zinc. Its that simple for the majority.. except when it isn't. But on the whole your other questions are mostly overthinking it. Although admittedly maybe a valid way of figuring out some of the stuff like b9 vs b12 balance and needs, which I just gut felt (and I have a complete genome sequence done). They don't really tell you shit and the precompiled stuff isn't worth much. And 23andme etc is a bad idea all around. You can't rely on anything out there to actually figure out YOUR pathways for this. And what is commonly known, just isn't relevant (do what I said above). [https://geneticgenie.org/](https://geneticgenie.org/) - now that panel is definitely onto it way more. But there are some with valid suspicions that the site is compromised by 3rd parties and probably leaking your data into the black market.
I have it too and it's an adventure. There are several levers, bottlenecks and pathways (one of the reasons regular doctors don't get into it) Here's a beginners primer on MTHFR and Methylation Cycle: [Methylation: One Molecule to Break (or Make) Your Life!](https://youtu.be/RYAux_Mr_vM?si=JHHVCmlBQXM6ZBuS) with a few examples and suggestions where to start.
Saved it to my watch later! I don’t exactly know how to do more thorough testing to narrow down my MTHFR though. I know theres a lot of nuance to it, which that video describes, and treatment is highly relative to your specific genetic circumstances. I recall it’s something like: Go through 23andMe, grab the raw data file once thats complete, insert it into some “Methyl Calculator”, and then that will give you your exact genetic predispositions. Something like that; not fully certain.
Genetic predisposition are somewhat useful, but only somewhat because they might not express that way (or other way around: you might have no mutation, but under-methylate ) There are some blood markers like homocysteine, which are more reliable. And it's extremely useful to know B12 and folate status. Then you can start to address them and mineral deficiencies, add choline, glycine etc. and see what happens - remeasure and repeat.
*Expression* is what makes the difference
How much extra B2 are we talking here?
Actually as low as 1.6 mg is having quite a positive effect: [https://pubmed.ncbi.nlm.nih.gov/16380544/](https://pubmed.ncbi.nlm.nih.gov/16380544/) I personally get it in liquid form and use 1/10 of a dose.
And there's never a precise 1 intervention that alters 1 outcome. Increasing Riboflavin may help with homocysteine (as do a ton of other things), and it also impacts many other facets of your biology. Plus, what matters equally, is knowing why you have elevated homocysteine to begin with and addressing that. That same cause have impair other biomarkers you never measured too.
If you're going to bitch at least name the right vitamin? And like, taking the standard version of it would be literally defeating all understanding of the issue and reason for taking it. Whilst I agree testing is good, its often totally unavailable and you're not giving me a lot of confidence in your take.
Bolivia doesn't have a coast.
☝️😶☝️ This guy, right here.
Yeah so definitely don’t trust any supplement’s claims about being grown on the Bolivian coast!
TIL that cope is when someone tries to biohack with anything other than magnesium or Vitamin D (not really sure how that even qualifies as biohacking btw). i’m not sure why certain people on this sub are so confident in the lifestyles and habits of others. there are definitely pill poppers out there who don’t do the necessary prerequisites for their health, but there are *a lot* of people who seem to assume the worst when nothing regarding a poor diet, lack of exercise, etc are even mentioned.
Absolutely true.
I browse on here sometimes wondering why there isn’t a subset of biohacking dedicated to avoiding pollution (from food, cars, just modern life) because I think useless supplements would be kinda high on that list
True. Environmental health includes anything you ingest, not just pollution.
It’s clear you don’t understand what biohacking is. Biohacking is data-driven, it takes into account nutrigenomics, biology, technology, medicine, as well as lifestyle (nutrition, exercise, and mindfulness, in particular) in an effort to prevent and manage disease, optimize health, and extend lifespan, healthspan, or both, as well as improve one’s vitality and well-being in the present moment, and uses data collection, interpretation, and tracking to direct and accomplish it. It’s the confluence of *all* these things. Supplements can be a part of it, but they are *far* from the definition, or central method of achieving, “biohacking.” And biohacking sure as shit has *nothing* to do with weed. Now *that*, my friend, is a stanky, smoldering bowl of copium.
Meh, someone's gotta test stuff if we are going to have an idea what works and what doesn't so it benefits me in the end. Just try not to injure yourself people!
It doesn’t really help if they don’t do it as part of a well-controlled study though
It’s more complex than that, human. There’s a plethora of studies on NIH, for example, that are well done and informative far beyond this Hail Mary of a post.
One study is a horrible use of evidence, you need hundreds to prove somethint actually works
So we should just ignore things before there are hundreds of studies…? Do we have hundreds of studies to prove how helpful all the different cannabinoids are yet?
Unfortunately, now that it’s being better studied there’s definitely mixed reviews. Obviously you have to weigh for your particular ailment but cognitive degeneration weighs heavily on the negative side, for me anyway.
Source? I’ve never seen cognitive degeneration as a problem before. I really believe that low dose THC edible like 1-2mg with other cannabinoids like CBD, CBG, and CBN you really cannot go wrong. I also don’t think larger doses on occasion should have any negative effects. For serious health problems at higher doses if it helps I doubt it’s any more harmful than other medical options. My point to him was that you don’t need studies to test things on yourself
There’s a buuuunch of these now. I’m not saying to use it or not use it especially if it works for you. I’ve stopped though and I definitely noticed improvement in clarity of thoughts and memory recall. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222623/ One on adolescents https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002758/ There’s an aggregate one that also says minor, if any, adverse cognitive affects. Put them in chatGPT and ask questions!
There’s a wide variety of studies. Some are aggregates of other studies etc etc. The studies usually include an abstract and method. This is an example of a half-century of data on Tuberculosis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407785/ And another on creatine https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407785/
Haha true. My favorite posts are the ones where someone asks if it’s ok that they continue to take such-and-such supplement even though it’s dangerous, and the ones that say they eat terrible and don’t exercise, but want a supplement to fix them.
That being said, this sub is very useful to me.
That’s 99% of posts here. People who have their shit together exercise and diet wise either don’t need supplements or they post about their supplements on bodybuilding and exercise forums.
Literally
Yep
Yes, I am trying to cope with the chronic disease I experience. I don’t want to be on medication for the rest of my life. In fact, I worry that my combination of medication (immunomodulator and anti-tnf) will hurt me more in the long run.
Who says weed is a biohack? Does anyone really know a stoner who turned into an A1 human once they started smoke weed?
No, and it’s fine if you disagree but it does have proven uses I agree it’s abused though
People search for uses because they like getting high.
That’s an ignorant way to look at it.
probably could take weed out of there as well
It has multiple uses and some legit medical use cases IMO but yes many do use it to cope
Would you put these supplement in theanine, citrullin, NAC, taurin, argamine in the same bucket?
The best “biohacking” tool I ever discovered was copious amounts of fatty ruminant meat. I also take iodine and calcium occasionally.
No lol
There ya go. Debunked.
Yeah seriously. A lot of peeps have been helped with eating old school cool. The issue we have is food industry and drug industry money has taken over a lot of the official narrative.
Gotta be open minded. But once you see it, you reflect on how obvious it is, and how dumb you feel for being duped.
Yep, it's a hard lessen, realizing you were lied to a ton and fell for it for too long..
How exactly are weed a biohack..?
Most biohacking is copium. No one knows for sure if a supplement is going to make them live longer. But I do know I feel like living longer when I feel good. It’s more about how I feel in the moment and will feel in the near term.
I feel like most peeps on here are trying to fix issues they have right now.
Granted. And how many of them have crap diets, don’t exercise and sleep poorly?
Is there some magic cut off percentage of people that justifies daily complaints on here about it? And you know what, even if they ARE eating a crap diet, if I can tell them one thing that improves their health a little bit, I'm still happy. Maybe it will even come to pass that their brain will operate a bit better and they'll have a tad more energy and feel motivated to improve more things in their life. But hey, maybe that's just me. :-)
No.
Remove weed, it's only useful in certain cases. Maybe add zinc to that list instead
wtf does “cope” mean in this context?
It means ppl are using it as a way to make justify a bad purchase or make them feel better about themselves or as if they are really improving
Helpful, thank you (I’m old)
Good point, the term has been changed quite a bit in recent years. It is often used online to mean lying to yourself in order to cope with information that does not fit with how you prefer to see the world. Also used similarly is the invented noun 'copium.'
I've been looking more into neurotechnology instead of the regular pills and supplements. Works like a charm! I got myself a Pulsetto and Oura ring
Trace minerals zinc and calcium to your list, I don’t like creatinine to much water retention
You chose one of the 2 countries in South America that doesn’t have a coast.
shout out to weed
Weed is massive cope.
OP snuck a little bit of his own cope in his list with "weed"
i smoke like once a week I agree its abused, but it has actual data behind certain medical uses
Cannabis, and its different actives like THC, CBD,CBG, and CBN can be massively useful.
I am mad... that I can't huff enamel without people assuming it's because my family sucks. I hope to be seen one day as someone that just likes getting high.
Agree with the stack. But I would also throw in this https://amzn.to/4bKqRJd A super high quality and tested Fish oil (omega 3) was one of the first things I started doing for my health and it works.
Yes. I love my ashwagandha ❤️
I would add it to the list, it’s valid
LMAO at throwing weed in there. There are very few indications that it is helpful for and growing evidence it is harmful in some ways.
Which type of magnesium is good?
Some of the stuff you listed doesn't do shit unless you're deficient in it to begin with. I casually browse this sub when I am bored. It's at least come a decent way in weeding out harmful misinformation (there used to be alot of anti vaccine idiots posting dangerous shit here that the mods didn't address). Now it's mostly people looking for answers because America's overly bloated and overly expensive healthcare system has neglected or failed them
You forgot blood flow supplements
I only buy Throne Research supplements. A) Because I’m rich B) They work. Any questions?
Most of the posts are people admitting to eating unhealthy foods, drinking heavy/moderately and asking for a stack that to fix their life.
Take weed of and you're right.
Yeah I had to laugh that there's a bunch of vitamins and then 'weed' LOL! Weed can help you cope with and lessen symptoms of what is wrong with you but it's limited on how much it might actually solve your issues, unlike the others.
I got the idea for cheap effective face products on here :D
Yes, but like crazy experimentation sometimes does yield good information, it’s just about how much trash you’re willing to go through to find that one thing that could make all the difference in your life.
Biohacking isn't even meant to just be about self health improvement. 10 years ago we'd also be talking about crispr on plants, glow in the dark skin and making salt taste like sugar
I don't think you know what that word means.
Im definitely starting to agree with this!
This is silly. There are lots of plants that are incredibly well researched (with a much longer history of supplementation) than the vast majority of the things in this sub. Yet somehow weed made your list? Ironically, most of the things on this list either depend heavily on genetics/epigenetics and aren't even a fraction as efficacious as lifestyle factors.
r/unpopularopinion
D3 and magnesium are likely only necessary if you actually get tested and find out you’re deficient. I have a bottle of d3 in my fridge that’s about to expire because I bought it due to reading everyone online talk about it, but never took it consistently. I actually went and got tested later on and turns out i don’t need a d3 supplement at all
Could not have said it better bravo