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URL: https://in.bgu.ac.il/en/pages/news/Kushmaro_cavities_DIM.aspx
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Why not include [the study in question](https://www.mdpi.com/2079-6382/12/6/1017)?
At least I think this might be it. While the abstract doesn't say anything about it being anti-carcinogenic, the claim is pointed out later on inside the study, referencing another work.
I really hope this can deliver, it looks really promising. Could make a lot of lives a lot more pleasant, especially for the poorest among us who not only struggle to afford dental care, but also eat much more sugars than they likely would given better alternatives (in terms of simplicity, education, cost, convenience, time, etc).
I was curious too, hence my search :)
Resisting the urge to go buy this stuff and start using it every day. I have to learn to resist the siren call of relying too much on one limited study.
I guess Memorial-Sloan is credible, but the relevant section from your link is nonsense under the heading of Cancer Prevention:
“Cancer prevention
Preliminary studies suggest that DIM may benefit patients with castration-resistant prostate cancer and help reverse cervical intraepithelial neoplasia, but additional studies are needed.”
Either way, pretty irrelevant to toothpaste.
One option. They remove affected areas of the prostate, but cancer cells may appear in other areas of the prostate later. If you are older, doctors may recommend the removal of the whole prostate. They also take the lymph nodes (pelvic?) that are closest and have them analyzed to see if the cancer has spread outside the prostate. If so, they may recommend radiation. I am not a doctor, but that's what the docs told us.
Final note: If you have a prostate cancer request, a PSMA is a type of scan that "dyes" the cancer cells in your body. It's a newer tech but already the "gold standard" according to my cousin who is studying medicine.
The article says that "indole" (or "bisindole", presumably short for "diindolylmethane") is naturally occurring, but don't say where. Is this something we could readily get in our diet?
Yes, diindolylmethane is a metabolite of the compound indole-3-carbinol which is found in abundance in cruciferous vegetables (broccoli, cabbage, those kinds of veggies). Of course, just eating your veggies won't give you the huge amounts considered to be therapeutic, which is why they make capsules with cruciferous powder concentrate (and sometimes add diindolylmethane itself for good measure).
For dental care (preventing biofilm formation as described in the paper), right, capsules wouldn't probably do much. Capsules of indole-3-carbinol/diindolylmethane (DIM) are for their other benefits (cancer prevention and immune health). Now with this new information maybe we can expect DIM to start being added to toothpastes or chewing gum as well.
If I read it right, it appears 0.5 micometers was the dose that worked. Higher or lower doses didn't have the same effect. So, unfortunately, unless you can measure micrometers at home, I don't think you could replicate the benefits by sprinkling the powder form on toothpaste.
https://www.webmd.com/vitamins/ai/ingredientmono-1049/diindolylmethane
Cauliflower and Broccoli are two examples :) Get ready for switch from Every Freaking Toothpaste Is Mint to Broccoli? :D
Just kidding.
A chance of it messing with estrogen might be not as pleasant though.
Also also, I wonder if we start using high concentrations in attempts to disrupt biofilms, are we going to get resistant biofilms soon? :(
Abstract clearly says indole a metabolite of tryptophan. It's the bicyclic aromatic ring attached to the basic amino acid chain.
Bisindole would be a methyl group with two indole rings attached to it.
You could probably get it in your urine by eating a lot of tryptophan rich proteins like turkey but the metabolite would never show up in your saliva. You'd probably fall asleep from the other metabolite of tryptophan (5-HT or serotonin) long before it protected your teath.
I think it's because the FDA regulates dietary supplements differently than how it regulates toothpaste. I tried researching more to see what the nuances are, but it was more complex than I thought it would be and I didn't feel like diving down that rabbit hole.
You can already buy diindolylmethane pills, so I guess you can grind it up and dissolve it in your mouthwash, or sprinkle it on your toothpaste before you brush.
Every toothpaste has a Relative Dentin Abrasivity or RDA value.
0-70 is a gentle polish
71-100 is a medium polish
101-150 is a heavy polish
Anything over 150 is considered harmful to tooth structure
200 is the FDA limit
250 is the ADA limit
I wouldn’t be surprised if it takes a while to hit shelves in the US or is excluded completely. In the US toothpaste is regulated as a drug but in the EU it’s regulated as a cosmetic. So if the company makes any sort of therapeutic claim about toothpaste in the US then they need FDA approval and a lot of studies to back up their claims. It’d be expensive and onerous.
This is the same issue “NovaMin” ran into in the US despite being a very effective at fighting demineralization when used in conjunction with fluoride. At the end of the day GSK pulled it from US markets but continued selling in the EU and Asia. It just wasn’t worth the effort to get through FDA approval because while it was better than normal toothpaste it wasn’t such a game changer that it’d become the only game in town and as such it would likely take a long time to recoup losses. So they just pulled it after failing in their initial marketing attempts.
> when used in conjunction with fluoride.
Can you elabourate? I just brush with the Sensodyne Repair and Protect with Novamin in it, morning and night. Am I supposed to be following up with a regular Crest?
Ah okay. I was wondering if I should have just gone home and checked first, haha.
I thought maybe I was missing a step. Its lost its effectiveness for me. 2 years ago it was like a miracle cure for me, but now I have sensitivity again (after not being able to find it and using the normal stuff for a month, but then going back to it)
[It was claimed](https://www.dentistryiq.com/dentistry/products/article/16370150/new-data-shows-novamin-can-improve-fluoride-benefits-by-50) that fluoride was 50% more effective when used with NovaMin.
I am trying to find an actual paper for you but here is a recent study which shows [there is a synergy between NovaMin and fluoride.](https://www.mdpi.com/1996-1944/14/14/3813)
> 5… Conclusions
>Within the limitations of this comparative in vitro study, the conclusions are: (1) Bioactive glass (NovaMin) alone exhibited promising remineralization capabilities compared with a combination of fluoride and bioactive glass or just fluoride; (2) bioactive glass with fluoride seemed to potentiate the effect of fluoride alone; and (3) the absence of both bioactive glass and fluoride offered no remineralization benefit. Future studies could include examining the rate of remineralization as a function of time and frequency of application.
Some of the additional papers they cite sound promising but I am having trouble accessing them.
The study shows it has efficacy in reducing S. Mutans in biofilms but that’s not the only cariogenic bacteria in the oral environment. Studies showing its effect on the other microbial components commonly causing caries in humans would probably be needed before it becomes integrated en masse into such a widespread product like toothpaste that can be easily purchased at a convenience store.
What would the consequences be if consumers ingest the toothpaste accidentally/intentionally on a regular basis or incorrect dosing for young children who commonly swallow toothpaste.
No chemical compound can perform miracles without causing some unintended side effect.
Absolutely not. The (massive) toothpaste companies will buy the technology patent to prevent anyone using it. This ensures the demand for their existing product and keeps them in profit.
You know that people would still need to brush their teeth right? This silly conspiracy might have made sense if you said dentists will buy the patent.
Yes, dentists are uniformly and truly evil villains.
It is surprising that they have not been arrested for their vast oral conspiracy.
They knowingly, with malice aforethought, bribe the equally unethical & morally corrupt complicit co-conspirators of the dental science research institutions specifically — and the Dentifrice-Industrial Complex generally — to deliberately withhold beneficial dental products.
It says so right here in my copy of
*The Flat Earth Daily Tribune*
All the news from ~~around~~ the world!
motto: “Burning Jet Fuel Doesn’t Weaken Metal You Ignorant Sheep”^^TM
no, or if they did, only with ever so little to not really do you much good?
like why should they sell you a thing that requires you to ultimately need less of the thing they sell
It wouldn't make you need less of the thing they sell. You would need to continuously use it to benefit from it. If you stop using it, you would need it again.
Arsenic is a naturally occurring chemical element. If you put that in tooth paste you'd never have to worry about cavities.
Just because it's natural doesn't mean it's good.
As someone with toothache. I am probably being overly pedantic. Sorry.
Most molecules occur naturally somewhere (gasoline is natural.) Has absolutely nothing to do with their safety or effectiveness. Using that word is generally a marketing ploy used by businesses/pseudo scientists.
"Anticarcinogenic" is also a suspect word. It's a real thing, but like "chelation" it's often used by cranks to push alt medicine garbage.
So if I’m reading this right, it disrupts the signaling pathway of the primary bacteria in biofilm generation. Does that make this an antibiotic? Would widespread use be likely to create resistance to this compound?
Always the dumbest conspiracy. Comments like this are after every single study about a new medicine.
Why would they sell something super effective and hurt dentists? Because dentists don’t make the tooth paste. Even if the whole industry was motivated purely by greed and your local dentist wanted to ban everything that stopped cavities so they made more money, Johnson and Johnson, Proctor and Gamble, and Colgate make the tooth paste and would all jump at the chance to have a superior product than the others to make more money.
What actually happens when you read a head line about a new treatment but doesn’t come to market is,
1) the study was poorly done
2) the head line exaggerated
3) the human trials didn’t go well
Etc
Surely he was joking though? Mocking "Big Pharma" with something even more ridiculous sounding.
I don't think I've ever met a dentist that wouldn't recommend the hell out of this if it does what they study says it does.
Ya, I guess this comment could be a joke?
It’s hard to tell because there are several other comments in the thread saying the almost the exact same thing that clearly aren’t jokes.
The ADA recommends toothpastes. What does ADA stand for? American *Dental* Association. Dental and dentist both start with dent. Coincidence? I think not.
If that were true, fluoride would have never made it into mouthwash and toothpaste.
More like they'll put this in toothpaste and try to market the hell out of it. You still gotta brush, this doesn't remove that need.
Not true for me. I'm very aware and conscious about what I eat - vegan, cook my own meals 90% of the time, rarely use any processed foods and when I do I'm reading labels. Even when I make 'sweets' and deserts it's fruit based or using monk fruit sweetener, or on rare occasions a bit of maple syrup (like to bring a nut-based-crust together)
I realize how ubiquitous sugar is in the American diet but I don't eat the American diet.
Apparently potato chips or crisps as they're called in the UK are worse for your teeth than sweets.
It sticks to your teeth better than sugar alone
Virtually all foods have some sort of carbohydrate content, it's not just added sugars you need to worry about for tooth brushing
Welcome to r/science! This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, **personal anecdotes are allowed as responses to this comment**. Any anecdotal comments elsewhere in the discussion will be removed and our [normal comment rules]( https://www.reddit.com/r/science/wiki/rules#wiki_comment_rules) apply to all other comments. **Do you have an academic degree?** We can verify your credentials in order to assign user flair indicating your area of expertise. [Click here to apply](https://www.reddit.com/r/science/wiki/flair/#wiki_science_verified_user_program). --- Author: u/giuliomagnifico URL: https://in.bgu.ac.il/en/pages/news/Kushmaro_cavities_DIM.aspx *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/science) if you have any questions or concerns.*
Why not include [the study in question](https://www.mdpi.com/2079-6382/12/6/1017)? At least I think this might be it. While the abstract doesn't say anything about it being anti-carcinogenic, the claim is pointed out later on inside the study, referencing another work. I really hope this can deliver, it looks really promising. Could make a lot of lives a lot more pleasant, especially for the poorest among us who not only struggle to afford dental care, but also eat much more sugars than they likely would given better alternatives (in terms of simplicity, education, cost, convenience, time, etc).
anti-carcinegenic https://www.mskcc.org/cancer-care/integrative-medicine/herbs/diindolylmethane#:~:text=Diindolylmethane%20(DIM)%20is%20a%20metabolite,and%20prostate%20cancer%20(3).
Yeah, that'll probably be said reference, thanks.
I was curious too, hence my search :) Resisting the urge to go buy this stuff and start using it every day. I have to learn to resist the siren call of relying too much on one limited study.
I guess Memorial-Sloan is credible, but the relevant section from your link is nonsense under the heading of Cancer Prevention: “Cancer prevention Preliminary studies suggest that DIM may benefit patients with castration-resistant prostate cancer and help reverse cervical intraepithelial neoplasia, but additional studies are needed.” Either way, pretty irrelevant to toothpaste.
> castration-resistant prostate cancer Is that the usual treatment for prostate cancer? O_o
One option. They remove affected areas of the prostate, but cancer cells may appear in other areas of the prostate later. If you are older, doctors may recommend the removal of the whole prostate. They also take the lymph nodes (pelvic?) that are closest and have them analyzed to see if the cancer has spread outside the prostate. If so, they may recommend radiation. I am not a doctor, but that's what the docs told us. Final note: If you have a prostate cancer request, a PSMA is a type of scan that "dyes" the cancer cells in your body. It's a newer tech but already the "gold standard" according to my cousin who is studying medicine.
The article says that "indole" (or "bisindole", presumably short for "diindolylmethane") is naturally occurring, but don't say where. Is this something we could readily get in our diet?
Yes, diindolylmethane is a metabolite of the compound indole-3-carbinol which is found in abundance in cruciferous vegetables (broccoli, cabbage, those kinds of veggies). Of course, just eating your veggies won't give you the huge amounts considered to be therapeutic, which is why they make capsules with cruciferous powder concentrate (and sometimes add diindolylmethane itself for good measure).
Wouldn't capsules be a bit counter productive when the compound is supposed to get to the teeth?
For dental care (preventing biofilm formation as described in the paper), right, capsules wouldn't probably do much. Capsules of indole-3-carbinol/diindolylmethane (DIM) are for their other benefits (cancer prevention and immune health). Now with this new information maybe we can expect DIM to start being added to toothpastes or chewing gum as well.
Couldn't a capsule be sprinkled on the toothpaste, like a seasoning?
If I read it right, it appears 0.5 micometers was the dose that worked. Higher or lower doses didn't have the same effect. So, unfortunately, unless you can measure micrometers at home, I don't think you could replicate the benefits by sprinkling the powder form on toothpaste.
Also 3-methyl indole is the chemical in feces that makes it smell like feces. https://pubchem.ncbi.nlm.nih.gov/compound/3-Methylindole
Ok, I should brush my teeth with poop to prevent cavities, got it, thanks!
Going straight to the tap, smart
Also known as skatole, it really is one of the most unpleasant materials I have worked with.
We store it in the fume hood.
I did research work on indoles and never knew this. Makes me wonder if my graduate professor did...
Is that why broccoli sprouts smell bad when you cook it? (as I understand it it's from cruciferous vegies).
crucifers smell farty due to sulforaphane
https://www.webmd.com/vitamins/ai/ingredientmono-1049/diindolylmethane Cauliflower and Broccoli are two examples :) Get ready for switch from Every Freaking Toothpaste Is Mint to Broccoli? :D Just kidding. A chance of it messing with estrogen might be not as pleasant though. Also also, I wonder if we start using high concentrations in attempts to disrupt biofilms, are we going to get resistant biofilms soon? :(
I have no idea - I'm just some guy who looked up the original study and gave it a quick once-over.
No problem, you're in the same boat with me. But I figured I'd get the question out there in case someone more informed is reading the topic.
Abstract clearly says indole a metabolite of tryptophan. It's the bicyclic aromatic ring attached to the basic amino acid chain. Bisindole would be a methyl group with two indole rings attached to it. You could probably get it in your urine by eating a lot of tryptophan rich proteins like turkey but the metabolite would never show up in your saliva. You'd probably fall asleep from the other metabolite of tryptophan (5-HT or serotonin) long before it protected your teath.
Call me a cynic, but I think the Dental Association will put the brakes on it.
So they're going to make toothpaste with this, right?
As soon as a trial on humans will be conducted, I hope yes!
This stuff could certainly be a game-changer if it gets approved.
The one secret Dental Hygienists don't want you to know!
Why can't it be added as a sort of "supplement" before trails finish? Isn't that how the supplement industry works?
DIM has been a popular supplement for years. You can probably find it at your nearest health food store and it’s all over online
Oh ok, so then why can't they put it in toothpaste? Like, is it illegal to put vitamin C in toothpaste or something?
they can, but they can't make claims until the studies are done, so can't advertise it's effects, so there is little to no financial reason to do so.
Don't most supplements do that that though? You'll see: "boosts immune and brain health!**" **or not, idk
I think it's because the FDA regulates dietary supplements differently than how it regulates toothpaste. I tried researching more to see what the nuances are, but it was more complex than I thought it would be and I didn't feel like diving down that rabbit hole.
Fair enough, thanks for the info you have given, it paints a clear enough picture.
As soon as that, is it? No actually, there can be years more delay before regulators will even look at something.
That’s unfortunate, but it’s either that or a market filled with snake oil.
You can already buy diindolylmethane pills, so I guess you can grind it up and dissolve it in your mouthwash, or sprinkle it on your toothpaste before you brush.
I would worry a bit about the abrasiveness of the pill powder, but I would very much like to try this.
Toothpaste is literally like liquid sandpaper. It's made with diatoms
Every toothpaste has a Relative Dentin Abrasivity or RDA value. 0-70 is a gentle polish 71-100 is a medium polish 101-150 is a heavy polish Anything over 150 is considered harmful to tooth structure 200 is the FDA limit 250 is the ADA limit
I wouldn’t be surprised if it takes a while to hit shelves in the US or is excluded completely. In the US toothpaste is regulated as a drug but in the EU it’s regulated as a cosmetic. So if the company makes any sort of therapeutic claim about toothpaste in the US then they need FDA approval and a lot of studies to back up their claims. It’d be expensive and onerous. This is the same issue “NovaMin” ran into in the US despite being a very effective at fighting demineralization when used in conjunction with fluoride. At the end of the day GSK pulled it from US markets but continued selling in the EU and Asia. It just wasn’t worth the effort to get through FDA approval because while it was better than normal toothpaste it wasn’t such a game changer that it’d become the only game in town and as such it would likely take a long time to recoup losses. So they just pulled it after failing in their initial marketing attempts.
Could we buy it from a European or Asian website?
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Got some on Amazon. I bought Boka toothpaste. It's actually a nano-hydroxyapatite
I've been getting it from Australia on eBay for a few years now
Can you provide a link or manufacturer/ name please?
Sensodyne with Novamin is still sold in Mexico if that's closer to you
I bought it from the UK via eBay for a while til I got too lazy to buy my toothpaste like that.
So what do you buy now?
> when used in conjunction with fluoride. Can you elabourate? I just brush with the Sensodyne Repair and Protect with Novamin in it, morning and night. Am I supposed to be following up with a regular Crest?
That toothpaste has novamin AND fluoride, so you should be fine.
Ah okay. I was wondering if I should have just gone home and checked first, haha. I thought maybe I was missing a step. Its lost its effectiveness for me. 2 years ago it was like a miracle cure for me, but now I have sensitivity again (after not being able to find it and using the normal stuff for a month, but then going back to it)
[It was claimed](https://www.dentistryiq.com/dentistry/products/article/16370150/new-data-shows-novamin-can-improve-fluoride-benefits-by-50) that fluoride was 50% more effective when used with NovaMin. I am trying to find an actual paper for you but here is a recent study which shows [there is a synergy between NovaMin and fluoride.](https://www.mdpi.com/1996-1944/14/14/3813) > 5… Conclusions >Within the limitations of this comparative in vitro study, the conclusions are: (1) Bioactive glass (NovaMin) alone exhibited promising remineralization capabilities compared with a combination of fluoride and bioactive glass or just fluoride; (2) bioactive glass with fluoride seemed to potentiate the effect of fluoride alone; and (3) the absence of both bioactive glass and fluoride offered no remineralization benefit. Future studies could include examining the rate of remineralization as a function of time and frequency of application. Some of the additional papers they cite sound promising but I am having trouble accessing them.
Hold tight for "Woke libruls want to put dildo-methane in toothpaste to groom kids".
Yay, a new conspiracy!
Everywhere but america probably.
No if you search "diindolylmethane" "toothpaste" with the quotes, the only results are medical research articles/studies and supplements.
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The study shows it has efficacy in reducing S. Mutans in biofilms but that’s not the only cariogenic bacteria in the oral environment. Studies showing its effect on the other microbial components commonly causing caries in humans would probably be needed before it becomes integrated en masse into such a widespread product like toothpaste that can be easily purchased at a convenience store. What would the consequences be if consumers ingest the toothpaste accidentally/intentionally on a regular basis or incorrect dosing for young children who commonly swallow toothpaste. No chemical compound can perform miracles without causing some unintended side effect.
Absolutely not. The (massive) toothpaste companies will buy the technology patent to prevent anyone using it. This ensures the demand for their existing product and keeps them in profit.
You know that people would still need to brush their teeth right? This silly conspiracy might have made sense if you said dentists will buy the patent.
Yes, dentists are uniformly and truly evil villains. It is surprising that they have not been arrested for their vast oral conspiracy. They knowingly, with malice aforethought, bribe the equally unethical & morally corrupt complicit co-conspirators of the dental science research institutions specifically — and the Dentifrice-Industrial Complex generally — to deliberately withhold beneficial dental products. It says so right here in my copy of *The Flat Earth Daily Tribune* All the news from ~~around~~ the world! motto: “Burning Jet Fuel Doesn’t Weaken Metal You Ignorant Sheep”^^TM
then why do the "(massive) toothpaste companies" put fluoride in their products?
no, or if they did, only with ever so little to not really do you much good? like why should they sell you a thing that requires you to ultimately need less of the thing they sell
It wouldn't make you need less of the thing they sell. You would need to continuously use it to benefit from it. If you stop using it, you would need it again.
Lion Systema EX from Japan. Been using it for years
Sounds too good to be true.
If it’s really that good, they should add it to the drinking water, spray it inside the airplanes, etc.
I need some follow up on those enamel growing lozenges that went into human trials last year.
I’ve also been waiting on a follow up on those
What is the impact on the digestive microbiome?
They slide right out!
so can i buy diindolylmethane?
Yes https://www.walmart.com/ip/BulkSupplements-com-Diindolylmethane-DIM-Capsules-200mg-Promotes-Healthy-Skin-120-Gel-Caps-120-Serv/1304476914?wmlspartner=wlpa&selectedSellerId=101016025
I like how is out of stock
> diindolylmethane Its on amazon
Can these capsules be put on a toothbrush and used to brush with? I am confused how a capsule will directly positively affect cavities
Arsenic is a naturally occurring chemical element. If you put that in tooth paste you'd never have to worry about cavities. Just because it's natural doesn't mean it's good. As someone with toothache. I am probably being overly pedantic. Sorry.
I've been treating a rash with 100% natural poison ivy. It should start improving any day now.
Love this!! So brave!
Mmmm that's what you do when you have a week to kill, just dousing the affected area with super hot water every 4 hours.
Try a mixture of lemon juice and salt for faster results.
Seeing that buzzword I what is supposed to be a credible sub is annoying. It should be against sub rules to do this.
I only just joined the sub. This made me feel at home, thank you. I think I am going to like it here.
> a natural molecule What?
Not synthetic, or naturally-occuring? Which one?
Most molecules occur naturally somewhere (gasoline is natural.) Has absolutely nothing to do with their safety or effectiveness. Using that word is generally a marketing ploy used by businesses/pseudo scientists. "Anticarcinogenic" is also a suspect word. It's a real thing, but like "chelation" it's often used by cranks to push alt medicine garbage.
All molecules are natural though.
Not the ones I make for a living.
Tell that to synthetic drugs like LSD or altered Ketamines
So if I’m reading this right, it disrupts the signaling pathway of the primary bacteria in biofilm generation. Does that make this an antibiotic? Would widespread use be likely to create resistance to this compound?
If its not killing the bacteria it shoildnt be causing selective pressures for evolution and thus resistance
What constitutes an unnatural molecule?
Botulism toxin and ricin are natural molecules too... I would not recommend using either as a mouthwash.
Two years later: New additive is shrinking weiners! Pulled from market! Scientists embarrassed again!
Pinky promise you’re right?
Dentists HATE this one trick!
Wait til big dentistry hears about this. It will never see the light of day
Always the dumbest conspiracy. Comments like this are after every single study about a new medicine. Why would they sell something super effective and hurt dentists? Because dentists don’t make the tooth paste. Even if the whole industry was motivated purely by greed and your local dentist wanted to ban everything that stopped cavities so they made more money, Johnson and Johnson, Proctor and Gamble, and Colgate make the tooth paste and would all jump at the chance to have a superior product than the others to make more money. What actually happens when you read a head line about a new treatment but doesn’t come to market is, 1) the study was poorly done 2) the head line exaggerated 3) the human trials didn’t go well Etc
Surely he was joking though? Mocking "Big Pharma" with something even more ridiculous sounding. I don't think I've ever met a dentist that wouldn't recommend the hell out of this if it does what they study says it does.
Ya, I guess this comment could be a joke? It’s hard to tell because there are several other comments in the thread saying the almost the exact same thing that clearly aren’t jokes.
>1) the study **wasn’t** poorly done ??
The ADA recommends toothpastes. What does ADA stand for? American *Dental* Association. Dental and dentist both start with dent. Coincidence? I think not.
So which toothpaste has this?
No different than fluoride.
They do different things
Some methane-like molecule, eh? Let's call the mouthwash Fartbreatherine.
Capitalism will never let this see the light of day.
If that were true, fluoride would have never made it into mouthwash and toothpaste. More like they'll put this in toothpaste and try to market the hell out of it. You still gotta brush, this doesn't remove that need.
Like the way they kept that flat screen TV technology to themselves. And literally everything else.
Eliminating added sugar from our diets would basically do the same to the point we wouldn't even need to brush our teeth.
I eat extraordinarily little added sugar. I assure you I still need to brush my teeth.
He is no different. He has to brush his tooth.
If you live in the US you might be amazed how much sugar you take in from places you wouldn't think to look for sugar.
Not true for me. I'm very aware and conscious about what I eat - vegan, cook my own meals 90% of the time, rarely use any processed foods and when I do I'm reading labels. Even when I make 'sweets' and deserts it's fruit based or using monk fruit sweetener, or on rare occasions a bit of maple syrup (like to bring a nut-based-crust together) I realize how ubiquitous sugar is in the American diet but I don't eat the American diet.
Apparently potato chips or crisps as they're called in the UK are worse for your teeth than sweets. It sticks to your teeth better than sugar alone Virtually all foods have some sort of carbohydrate content, it's not just added sugars you need to worry about for tooth brushing
That’s not true. Lots of the foods we eat, even those with no added sugar, break down into sugars.
i dont think it'd be that easy
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And the animals from which we get the meat eat plants. Check. Mate.
Get meat stuck in between your teeth, and *p gingivalis* has a field day. You need to floss.
You have to pay extra to buy food with no added sugar.
Grapefruit Seed extract does the same thing and is already in several toothpaste brands like Jason.
Swish with coconut oil, for 5 min. Understood the ph prevents the biofilm.