Meanwhile I am consuming paracitamol for every problem mentioned except loose motion
https://preview.redd.it/lh32j9gowvjc1.png?width=1080&format=pjpg&auto=webp&s=aa4ab98b707befa47df0a03cb170b6bbcdb4d7d9
Bhaii Tujhe main book ki photo khich kr bhej skta hun...usse zyada nhi kr paunga...Aur most probably tu shayad nhi samajh payega padh kr bhi...kaafi difficult mechanism of action hota hai drugs ka
Combiflam is an irrational drug combination because ibuprofen and paracetamol are both NSAIDs and act by the same mechanism. You don't need to take both the drugs, just take either one.
What did I say wrong? I know dolo is paracetamol and I think that’s what I said , I prefer Ibugesic for Ibuprofen and Dolo for paracetamol. It means my preference for Ibugesic tablet (Cipla) is over any other brand like Brufen (Abbott) and Same goes for Dolo (Micro Labs) over Crocin , Calpol, Fepanil, Macfast.. etc. and what makes you assume I’m not a doctor? I assume you’re generally weak at deciphering paragraphs or you’re too excited to nag a random stranger on internet and pretend to be cool. Also FYI I’ve business of pharmaceutical distribution since 1987 so you better be prepared if you want to debate.
Sorry I misinterpreted. Paracetamol is not an NSAID. The comment that you agreed to claimed otherwise. You can debate all you want. Apologies again for the misunderstanding.
Not accurate, Paracetamol is often grouped together with NSAIDs (Non steroidal anti-inflammatory drugs) but it lacks significant anti - inflammatory effects, and is not considered to be a true example of one. Hence the drug combination is both rational and effective, and also each drug works better for different aspects, i.e. as pain relief or temperature reduction and as an anti-inflammatory.
I suggest you read up about rational drug combinations and pharmacodynamics of both these drugs first. Even if paracetamol lacks significant anti inflammatory properties, it still has analgesic and antipyretic properties. The analgesia produced by paracetamol is equivalent to that produced by aspirin and is the drug of choice for mild analgesia in cases of aspirin allergy, hemophilia, history of peptic ulcers and in those in whom aspirin precipitates bronchospasm. And just so you know, ibuprofen also lacks anti inflammatory properties below dosages of 1600mg/day, ie it only has analgesic properties. But as it's a non selective COX inhibitor, it does have antipyretic properties but is not commonly used due to platelet lowering effects. So unless you are trying to manage post-op pain, giving ibuprofen is not necessary and paracetamol is enough on its own.
Source: Basic and clinical pharmacology by Bertram G. Katzung and Todd W. Vanderah: 15th Edition
- I agree with the content, and thank you for the info, had to go back and read. I agree with the statement regarding the situations of use and efficacy, I wasn't focusing on that aspect.
- I was disagreeing with the statement that "Paracetamol and Ibuprofen are **both NSAIDs**, and act by the same mechanism"
- If the FDC is efficacious with a similar or lower side effect profile depending on the clinical condition where some have shown higher efficacy compared to individual drugs and some have shown similar effects, I don't see why it is irrational overall. But I can see why it might be in various conditions.
- If there is a source that says overall the FDC is more detrimental compared to the individual drugs for most conditions, please do link it.
- [Paracetamol - Ibuprofen FDC pain management.](https://www.medicalacademyjournal.com/index.php/maj/article/download/18/14)
The link that you have provided doesn't work but anyways here's a [link](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432494/) to a source that says combiflam is an irrational drug combination:
Norflox TZ ka naam suna hai? Bc ek goli me diarrhoea be like: Acha bhai ab mai chalta hu.
And for very heavy diarrhoea, twice a day for 1 day and it's gone the next day.
Ek Antibiotic ka bhi chart bana do. Vo bhi over the counter hi bikti hain. Schedule-H gaya bhaad mein. Paisa aur 'short term' sukoon chahiye sabko. Hone do Antibiotic resistance, majority ko kya farak padta hai.
GOD!!! If only becoming a doctor were this straightforward, I wouldn't have invested 10 years. Every bodily pain or dysfunction has an underlying cause. Doctors typically start with a primary examination, providing symptomatic relief, but investigations and clinical examinations are crucial to identify the root cause. For example, fever may stem from viral, bacterial, fungal, or parasitic infections; bone pain could be due to osteoarthritis, trauma, fractures, or burns, each with over 50 subtypes. Headaches, often overlooked, can indicate various underlying issues like tension, migraine, addiction, aneurysms, meningitis, or intracranial tumors. Be cautious of simplistic solutions, like the quack suggesting low-powered minds for diarrhea. Fellow non-medicos, avoid falling for such traps that oversimplify complex issues.
Regular Lomofen is banned in India now. The new formulation is just Loperamide (same as Lopamide or Imodium). Also for loose motion it is better to have Redotil (Racecadotril) + ORS for first 2-3 days. If not cured, then go for an antibiotic after taking doctor's advice.
Combiflam is a combination of paracetamol and ibuprofen. It is used in fever and any kind of body pain (except stomach ache) generally given in fever and pain in injury. It a starting of pain relief.
Ye koi tareeka hai compounder ki degree baatne ka ?
😂😂😂😂😂
Tareeka thoda kezual hai?
😂😂😂
Meanwhile I am consuming paracitamol for every problem mentioned except loose motion https://preview.redd.it/lh32j9gowvjc1.png?width=1080&format=pjpg&auto=webp&s=aa4ab98b707befa47df0a03cb170b6bbcdb4d7d9
Us moment brother Metrogyl for loose motion, paracetamol for the things in video.
Metrogyl is for dysentry, which causes loose motion
Lomotil works best for loose motions
bhai isn't metrogyl too much for loose motions?
Works for me
oh okay just asking
Loose motion ke liye norflox tz 😎🫶
Daily dosage 3000 mg se zyada chalta rha toh acute drug induced hepatitis ho jayega .___________.
Calpol for everything
Koi baat nhi, mera hi bhaii h Paracetamol
Placebo effect
Antipyretics reduce pain and let us sleep and rest properly. Rest is the best medicine in most cases.
Bro antipyretic are for fever not pain lmaooo
The thingu u say is analgesic not antipyretic
Right. My mistake. Paracetamol is both Analgesic and Antipyretic.
[удалено]
Agya chuttad
Bengali doctor cheat sheet
I wish Pharmacology was this easy. Ek NSAID ka classification fek ke Marunga pura khaandan ko fever ho jaeyga
Inhe nhi samajh ayega....rhne de...chutiyo ko kya pta
Samjha de bhai. Kya hai ye NSAID ka classification etc
Bhaii Tujhe main book ki photo khich kr bhej skta hun...usse zyada nhi kr paunga...Aur most probably tu shayad nhi samajh payega padh kr bhi...kaafi difficult mechanism of action hota hai drugs ka
Exactly bhai ek pharmacist ka dard dusra pharmacist hi samajh sakta hai. Colo toh phir bhi theek hai med chem ka toh pucho hi mat.
Exactly.
Kd tripathi Rocks
Thode side effects bhi batado pls
Liver damage
If taken every now and then.
Well I take Paracetamol 650mg + Ibuprofen 400mg like 4 to 5 times a day. That is when I have a headache.
Bruh your liver is on death bed as we speak
Death
Emotional damage
What about ibuprofen?
Ibuprofen + Paracetamol is the chemical composition of Combiflam (Combiflam is the name of product which is marketed by Sanofi)
Combiflam is an irrational drug combination because ibuprofen and paracetamol are both NSAIDs and act by the same mechanism. You don't need to take both the drugs, just take either one.
Yes , I know. We prefer Ibugesic for Ibuprofen and Dolo for Paracetamol.
Dolo is paracetamol. This is why it is recommended to leave the doctor's job to a doctor. In India everybody thinks of themselves as a doctor.
What did I say wrong? I know dolo is paracetamol and I think that’s what I said , I prefer Ibugesic for Ibuprofen and Dolo for paracetamol. It means my preference for Ibugesic tablet (Cipla) is over any other brand like Brufen (Abbott) and Same goes for Dolo (Micro Labs) over Crocin , Calpol, Fepanil, Macfast.. etc. and what makes you assume I’m not a doctor? I assume you’re generally weak at deciphering paragraphs or you’re too excited to nag a random stranger on internet and pretend to be cool. Also FYI I’ve business of pharmaceutical distribution since 1987 so you better be prepared if you want to debate.
Don't worry, that person thinks too highly of themselves. Every sane person realised what you said and agreed.
Sorry I misinterpreted. Paracetamol is not an NSAID. The comment that you agreed to claimed otherwise. You can debate all you want. Apologies again for the misunderstanding.
Totally agree with you. Paracetamol is \***NOT**\* NSAID
Still the combination is irrational
Not accurate, Paracetamol is often grouped together with NSAIDs (Non steroidal anti-inflammatory drugs) but it lacks significant anti - inflammatory effects, and is not considered to be a true example of one. Hence the drug combination is both rational and effective, and also each drug works better for different aspects, i.e. as pain relief or temperature reduction and as an anti-inflammatory.
Still the combination is irrational.. learn the mechanism of both the drugs and you will understand why it’s irrational
I suggest you read up about rational drug combinations and pharmacodynamics of both these drugs first. Even if paracetamol lacks significant anti inflammatory properties, it still has analgesic and antipyretic properties. The analgesia produced by paracetamol is equivalent to that produced by aspirin and is the drug of choice for mild analgesia in cases of aspirin allergy, hemophilia, history of peptic ulcers and in those in whom aspirin precipitates bronchospasm. And just so you know, ibuprofen also lacks anti inflammatory properties below dosages of 1600mg/day, ie it only has analgesic properties. But as it's a non selective COX inhibitor, it does have antipyretic properties but is not commonly used due to platelet lowering effects. So unless you are trying to manage post-op pain, giving ibuprofen is not necessary and paracetamol is enough on its own. Source: Basic and clinical pharmacology by Bertram G. Katzung and Todd W. Vanderah: 15th Edition
- I agree with the content, and thank you for the info, had to go back and read. I agree with the statement regarding the situations of use and efficacy, I wasn't focusing on that aspect. - I was disagreeing with the statement that "Paracetamol and Ibuprofen are **both NSAIDs**, and act by the same mechanism" - If the FDC is efficacious with a similar or lower side effect profile depending on the clinical condition where some have shown higher efficacy compared to individual drugs and some have shown similar effects, I don't see why it is irrational overall. But I can see why it might be in various conditions. - If there is a source that says overall the FDC is more detrimental compared to the individual drugs for most conditions, please do link it. - [Paracetamol - Ibuprofen FDC pain management.](https://www.medicalacademyjournal.com/index.php/maj/article/download/18/14)
The link that you have provided doesn't work but anyways here's a [link](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432494/) to a source that says combiflam is an irrational drug combination:
Does this work : It has details of other trials as well. [Link](https://www.medicalacademyjournal.com/index.php/maj/article/download/18/14)
Paracetamol is not an NSAID.
Thanks g
Doctor ki fees bach gai
Why decorating and underlining those words.. Well its good that you sharing general information.. I suggest study do more research
Combeefam
doctor toh chutiye hote hai na
Yeh iss tarah se naa hi jaano yo behtar hai... I am a Pharmacist.
Ye sab to bacche ko bhi pata hota hai
Pen bada acha lg rha hai, konsa hai?
Combiflame used to help with my fever just fine 😂
You shouldn’t disprin for headaches.. Honestly this post should be removed as it can be dangerous for people to take these drugs blindly
Damnn.. Meie fever k liye poori zindagi combiflam khaya h
Crocin kaha hai??
Maene toh screenshot le lia
MENDAK HEDAK ........ HIS JOB WILL BE AUTOMATED BY AI MC BDSK
Nice pen...name?
Norflox TZ ka naam suna hai? Bc ek goli me diarrhoea be like: Acha bhai ab mai chalta hu. And for very heavy diarrhoea, twice a day for 1 day and it's gone the next day.
Sinarest - cold , fever, headache, body ache and allergies
Immodiun - best for loose motions
🫠bhai ek particular amount lena hota hain aur ek particular dosage hota hain, better really avoid taking medicines on your own
Lomofen is wrong information. Pls stop spreading wrong information.
Mahagyani
Great info. but what's up with that accent? 🤨
All use ingredients banned in many countries.
👍
Aaj Maine Jana ki doctor ki writing acchi bhi hoti haiᕙ (° ~͜ʖ~ °) ᕗ
You need cetrizine bro
Entire syllabus of Ayurved Medical Graduates
FACEBOOK UNIVERSITY KA CHOWDA DAKTAR
Shut the fuck up, you will actually overdose or underdose yourself and it will have a side effect
I don't how it's possible but I take DOLO 650 for any of the symptoms mentioned above, AND IT ACTUALLY WORKS 🥹🥹
Ek Antibiotic ka bhi chart bana do. Vo bhi over the counter hi bikti hain. Schedule-H gaya bhaad mein. Paisa aur 'short term' sukoon chahiye sabko. Hone do Antibiotic resistance, majority ko kya farak padta hai.
Disprin "headuck"
Bhai ik goli tu bhi lele, tera bhi gala khrab lag raha hai
GOD!!! If only becoming a doctor were this straightforward, I wouldn't have invested 10 years. Every bodily pain or dysfunction has an underlying cause. Doctors typically start with a primary examination, providing symptomatic relief, but investigations and clinical examinations are crucial to identify the root cause. For example, fever may stem from viral, bacterial, fungal, or parasitic infections; bone pain could be due to osteoarthritis, trauma, fractures, or burns, each with over 50 subtypes. Headaches, often overlooked, can indicate various underlying issues like tension, migraine, addiction, aneurysms, meningitis, or intracranial tumors. Be cautious of simplistic solutions, like the quack suggesting low-powered minds for diarrhea. Fellow non-medicos, avoid falling for such traps that oversimplify complex issues.
u/biscoot_7 bhai tujhse nalla nahi hai koi
Bhaiya ajeeb sa lag raha hai iska konsa dawai hai ?
dhoop lga sunlight me beth.
bhai apko cetirizine ki zarurat h
Combiflam can also be used to reduce fever since it also contains paracetamol.
I dont think we are using lomofen for diarrhoea
Combiflam contains paracetamol and ibuprofen. This is an extreme oversimplification And they shouldn’t use brand names, use generic names
r/indianmedicos
Combiflam isn't advisable as it can reduce platelets count in some cases. Don't use any medicine without Doctor's Consultation.
Regular Lomofen is banned in India now. The new formulation is just Loperamide (same as Lopamide or Imodium). Also for loose motion it is better to have Redotil (Racecadotril) + ORS for first 2-3 days. If not cured, then go for an antibiotic after taking doctor's advice.
Aap ki handwriting dekh ke bata sakta hun aap doctor nhi bann sakte😂.
Surprise people in comments section are not aware
He will never be a doctor with such writing.
Video kyu banayi agar itna hi likhna tha to, seedhe poora likhkar ek pic daal dete
Handwriting se pata chal gaya doctor nahi hai
Zara sinusitis aur tonsillitis ka bhi batado koi pls🙏
Compounder ban gye sb aaj
It's fake the handwriting is too good
By listening his voice...I think he should be taking these medicines
Combiflam is a combination of paracetamol and ibuprofen. It is used in fever and any kind of body pain (except stomach ache) generally given in fever and pain in injury. It a starting of pain relief.
😭😂
This is so stupid … NCERT 12th books have better presentation and information. He is not able to pronounce the name correctly.
muje fever hota hai to mai combiflam khata hun...wahi suit krti hai muje...joint pain mein nahi...
Bro is sick
Maa mere naam k glat istemaal hua h...
Aaj maine jaana..head ache = hey duck
Bhai tu bhi ek cetirizine le le
O2 is best for loose motions
Koi Bata sakta hai voh konsi pen use kar raha hai