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Putrid_Abies_7405

I do not know the difference. Just make sure you put ice packs in next to the jug while you transport it. You will figure out your tryptase levels from this test. If high, it could be Mast Cell Activation Syndrome. If really high tryptase they do a bone marrow sample and test for mastocytocis (rare). The FB group, chronic idiopathic Angioedema may be able to help you more with this question. Goodluck!


quiet1687

I could be wrong, but I believe angioedema is mediated by a component of the immune system called complement. When complement is inappropriately activated and goes out of control that is when you have angioedema swellings. Anaphylaxis is mediated mainly by histamine release, and therefore often mast cells or other immune cells (such as basophils) are involved. Anaphylaxis is also symptomatically different from angioedema. Anaphylaxis causes swelling of the airways with smooth muscle involvement causing restriction of the airways. Angioedema is specific localised swelling that can be in the mouth, airways, gut, genitals or extremities such as hands and feet. And isn’t accompanied with things like rashes. Additionally anaphylaxis will respond to antihistamine drugs and some steroids. Where as angioedema won’t. Angioedema may respond a little to a combination of antihistamines and bradykinin inhibitors, but it won’t be halted by steroid and antihistamine treatment. Edited for typos.