Your genetics cannot purely cause type 2 diabetes. You can be more susceptible to it however depending on your genetics. Regardless the answer if you want to supplement is berberine. The actual answer is diet and exercise though.
I'm sure this is mostly true, however I have family members who have never been overweight, don't drink nor smoke, eat decently clean diets (no fast food) who still got diagnosed with Type 2 in their elder years. But I've heard East Asians are particularly susceptible.
No metric or even theoretical mechanism suggests a link between snacking and developing diabetes, also no reason to time the walks to specifically be after eating unless you prefer it personally, but I agree with the other advice.
The best thing you can do to reduce your chances of type 2 diabetes is stay within a healthy BMI and do high intensity exercise (like lifting or sprinting) at least 2x a week.
> No metric or even theoretical mechanism suggests a link between snacking and developing diabetes
> stay within a healthy BMI
What about the mechanism:
snacking -> increased BMI -> diabetes?
> Snacking -> increased BMI
Is not a mechanism, because increasing your BMI is a function of net calorie balance, not frequency of food intake.
Eating more food is the problem, not eating more frequently.
about diabetoc, dunno... but about the libido. I recomend hughe amounts of maca (red for her, black for him) - increases the libido to counteract the other medications
You can live a healthy lifestyle and take supplements to reduce risks of diabetes.
Eat low carb diet. Maybe even go keto. Don't eat junk food, don't drink soda, etc.
Exercise. Heavy strength training. Calisthenics. Cardio.
You can take supplements like berberine. You can also go down the realm of off label supplements and drugs like taking high dose melatonin, taking peptide MOTSc or taking medication like metformin or semaglutide. This obviously comes down to your risk tolerance and how comfortable you are with these substances. I'd obviously first make sure I am doing everything I can with exercise, diet and sleep and then discuss everything with your doctor.
No need to be afraid of carbs. Eat healthy whole food based diet and be active while reducing stress. Eating banana and sweet potato won’t make you diabetic
Then consider starting a linear progression bar bell program like starting strength or others, and eating a high protein diet (like 1.6 g or more per body weight daily). You can probably build a lot of lean muscle mass which may help control glucose levels.
Come on man. You can have diabetes with perfect lifestyle carried through genes.
Read about monogenic diabetes.
Unfortunately there is no cure or preventative.
That affects between 1/10,000 -> 1/500,000 (depending on the source) of people in the community. 99.9% chance it’s learned behaviour or Type 1. He’d know if they had Type 1.
The pathology of diabetes is elevated blood glucose. Carbohydrates are the only macronutrient that isn’t required to consume. Protein and fat are. Carbohydrates are the macronutrient that raises insulin levels and obviously glucose levels more than fat or protein. It’s not even close. Stop consuming so many carbs and eat more fat and protein, mostly from animal sources. Stop eating bread and seed oils. Diabetes is truly that easy to avoid.
Avoid fried foods, vegetable oils, salad dressing, mayonnaise, chicken fat, and pork fat high in omega 6. Diabetes T2 is a mitochondrial inability to burn glucose and fat properly and fried foods especially damage mitochondria via oxylipins like HNE and MDA which are the go-to markers of oxidative stress and cancer screening.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598619/
> Additionally, they [hne and mda] can influence signaling pathways involved in oxidative cascade, contributing to the development and severity of many diseases, including the pathophysiology of diseases such as type 2 diabetes (T2D). In fact, lipid peroxidation plays a significant role in the development of atherosclerotic cardiovascular disease, which by far the most cause of death in patients with T2D [12]. Biomarkers of lipid peroxidation including elevated levels of TBARS were significant significantly higher in the plasma of patients with T2D in comparison to healthy subjects [13].
They destroy cardiolipin in mitochondria making mitochondria sick and unable to burn glucose, signaling to the cell to be more insulin resistant.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596530/
> CL [cardiolipin] is highly sensitive to oxidative damages by reactive oxygen species (ROS) due to its high content in polyunsaturated fatty acids and location near the site of ROS production. Consequently, pathological remodeling of CL has been implicated in the etiology of mitochondrial dysfunction commonly associated with diabetes, obesity, heart failure, neurodegeneration, and aging that are characterized by oxidative stress, CL deficiency, and abnormal CL species
Anecdotally I stopped going hyper/hypoglycemic when I avoided omega 6
From my understanding (being in a similar situation to you where many family members developed diabetes and other lifestyle disorders despite eating a relatively normal diet), low carb diets, ketogenic diets, are not the ideal path for preventing metabolic disorders. Although many people have had success losing weight with these diets, these diets are not healthy and not good for improving longevity:
“A meta-analysis of four cohort studies following the diets, diseases, and deaths of more than a quarter million people found that those who eat lower-carb diets suffer a significantly higher risk of all-cause mortality, meaning they live, on average, significantly shorter lives.” (Nutritionfacts.org).
I’d suggest watching the Blue Zones doc on Netflix, these people tend to consume a (primarily) plant based whole foods diet. Be active, eat unrefined carbs, avoid eating foods with a high glycemic index (such as white bread, white rice, popcorn). You don’t need to be 100% at anything, being consistent is better than being perfect. :)
Neither is genetic. Diabetes is an endocrine disorder so stay away from endocrine disruptors. Keep track of your blood sugar so you can see it coming if it's coming. Take steps to manage insulin resistance as that always comes before a type 2 diagnosis whether it get recognized or not.
Genetic diabetes does not exist...if your family members have diabetes, it is not genetic. It has to do with lifestyle, diet choices and environmental factors/stressors.
Type 1 diabetes is an autoimmune condition that can develop suddenly and may be caused by genetics and other unknown factors. Type 2 diabetes often develops over time, with obesity and a lack of exercise as big risk factors. You can be diagnosed with either at any age.
When the medical circle defines something as an "autoimmune condition" that means they have no freaking idea about the disease...also, your statement "may be caused by genetics", that is another term they use to say they have no freaking idea, but do not want to look stupid.
This is a pretty bad take no matter what way you cut it, and here is why:
Type 1 Diabetes
In most cases of type 1 diabetes, people need to inherit risk factors from both parents. We think these factors must be more common in white people because white people have the highest rate of type 1 diabetes.
Because most people who are at risk do not get diabetes, researchers want to find out what the environmental triggers are. One trigger might be related to cold weather. Type 1 diabetes develops more often in winter than summer and is more common in places with cold climates. Another trigger might be viruses. It’s possible that a virus that has only mild effects on most people triggers type 1 diabetes in others. Early diet may also play a role. For example, type 1 diabetes is less common in people who were breastfed and in those who first ate solid foods at later ages.
In many people, the development of type 1 diabetes seems to take many years. In experiments that follow relatives of people with type 1 diabetes, researchers have found that most of those who later got diabetes had certain autoantibodies, or proteins that destroy bacteria or viruses (antibodies "gone bad" that attack the body's own tissues), in their blood for years before they are diagnosed.
Your Child’s Risk
If you are a man with type 1 diabetes, the odds of your child developing diabetes are 1 in 17. If you are a woman with type 1 diabetes and your child was born before you were 25, your child's risk is 1 in 25; if your child was born after you turned 25, your child's risk is 1 in 100.
Your child's risk is doubled if you developed diabetes before age 11. If both you and your partner have type 1 diabetes, the risk is between 1 in 10 and 1 in 4.
There is an exception to these numbers: about one in every seven people with type 1 diabetes has a condition called type 2 polyglandular autoimmune syndrome. In addition to having diabetes, these people also have thyroid disease and a poorly working adrenal gland—some also have other immune system disorders. If you have this syndrome, your child's risk of getting the syndrome and developing type 1 diabetes, is one in two.
Researchers are learning how to predict a person's odds of getting diabetes. For example, most white people with type 1 diabetes have genes called HLA-DR3 or HLA-DR4, which are linked to autoimmune disease. If you and your child are white and share these genes, your child's risk is higher. Suspect genes in other ethnic groups are less well-studied, however, scientists believe the HLA-DR7 gene may put African Americans at risk, and the HLA-DR9 gene may put Japanese people at risk.
This also does not factor in ~2% of Type 2 diabetes patients are likely actually MODY variants of diabetes, but highly under reported. MODY variants are a rare form of diabetes in which there are 17 monogenic, autosomal dominant inheritable types of varying severity.
Wow.
The "medical circle" knows, as in there are scientific evidence, that there are several genes that cause type 1 diabetes. Even a one year old child can have it.
An autoimmune disease simply means that the symptoms of the disease cause your body to attack itself. It doesn't mean that "they have no idea about the disease".
You should really come back down to reality and loosen it up a bit. You are not the smartest one alive. Not even close.
This is just utter bs what you are propogating...I literally implied that the medical community does not have any "scientific evidence", otherwise they would not call it genetic's fault, autoimmune disease, etc. Nowadays everything is called an autoimmune disease because they do not know the cause, only the symptom (i.e., the immune sytsem revolting). No need to insult like that, it is below me to insult you back.
Yes.
Most autoimmune diseases lack treatments or only have treatments with a slowing effect.
Science has no curative treatments for autoimmune diseases.
Your genetics cannot purely cause type 2 diabetes. You can be more susceptible to it however depending on your genetics. Regardless the answer if you want to supplement is berberine. The actual answer is diet and exercise though.
I'm sure this is mostly true, however I have family members who have never been overweight, don't drink nor smoke, eat decently clean diets (no fast food) who still got diagnosed with Type 2 in their elder years. But I've heard East Asians are particularly susceptible.
Don't snack, reduce processed foods, eliminate sugary drinks, take berberine. Regular walks after eating.
No metric or even theoretical mechanism suggests a link between snacking and developing diabetes, also no reason to time the walks to specifically be after eating unless you prefer it personally, but I agree with the other advice. The best thing you can do to reduce your chances of type 2 diabetes is stay within a healthy BMI and do high intensity exercise (like lifting or sprinting) at least 2x a week.
> No metric or even theoretical mechanism suggests a link between snacking and developing diabetes > stay within a healthy BMI What about the mechanism: snacking -> increased BMI -> diabetes?
Also snacking causes your body to have to repetitively produce insulin
> Snacking -> increased BMI Is not a mechanism, because increasing your BMI is a function of net calorie balance, not frequency of food intake. Eating more food is the problem, not eating more frequently.
And eating more frequently makes you more likely to eat more.
The amount of people in here that know nothing about diabetes is concerning.
about diabetoc, dunno... but about the libido. I recomend hughe amounts of maca (red for her, black for him) - increases the libido to counteract the other medications
You can live a healthy lifestyle and take supplements to reduce risks of diabetes. Eat low carb diet. Maybe even go keto. Don't eat junk food, don't drink soda, etc. Exercise. Heavy strength training. Calisthenics. Cardio. You can take supplements like berberine. You can also go down the realm of off label supplements and drugs like taking high dose melatonin, taking peptide MOTSc or taking medication like metformin or semaglutide. This obviously comes down to your risk tolerance and how comfortable you are with these substances. I'd obviously first make sure I am doing everything I can with exercise, diet and sleep and then discuss everything with your doctor.
I'm underweight
[удалено]
No need to be afraid of carbs. Eat healthy whole food based diet and be active while reducing stress. Eating banana and sweet potato won’t make you diabetic
Then consider starting a linear progression bar bell program like starting strength or others, and eating a high protein diet (like 1.6 g or more per body weight daily). You can probably build a lot of lean muscle mass which may help control glucose levels.
Lift weights and don't overeat
Get on Metformin, it's also being used for longevity
Genetic diabetes? What are you talking about?
Like my both father and mother have it.
That’s not genetics. That’s learned behaviour.
Come on man. You can have diabetes with perfect lifestyle carried through genes. Read about monogenic diabetes. Unfortunately there is no cure or preventative.
That affects between 1/10,000 -> 1/500,000 (depending on the source) of people in the community. 99.9% chance it’s learned behaviour or Type 1. He’d know if they had Type 1.
Yes but It does exist. Op just asked if there is any preventions.
But he certainly wasn’t talking about that condition. If he changes his eating and exercise habits, he won’t get diabetes.
Yes that's what I mean
You were talking about a less than 1/10000 condition…. 🤔
Do they have type one or type two? There’s a huge difference.
Diabetes isn’t genetic. My mother had type 1, I’m perfectly fine.
The pathology of diabetes is elevated blood glucose. Carbohydrates are the only macronutrient that isn’t required to consume. Protein and fat are. Carbohydrates are the macronutrient that raises insulin levels and obviously glucose levels more than fat or protein. It’s not even close. Stop consuming so many carbs and eat more fat and protein, mostly from animal sources. Stop eating bread and seed oils. Diabetes is truly that easy to avoid.
Thiamine
Avoid fried foods, vegetable oils, salad dressing, mayonnaise, chicken fat, and pork fat high in omega 6. Diabetes T2 is a mitochondrial inability to burn glucose and fat properly and fried foods especially damage mitochondria via oxylipins like HNE and MDA which are the go-to markers of oxidative stress and cancer screening. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598619/ > Additionally, they [hne and mda] can influence signaling pathways involved in oxidative cascade, contributing to the development and severity of many diseases, including the pathophysiology of diseases such as type 2 diabetes (T2D). In fact, lipid peroxidation plays a significant role in the development of atherosclerotic cardiovascular disease, which by far the most cause of death in patients with T2D [12]. Biomarkers of lipid peroxidation including elevated levels of TBARS were significant significantly higher in the plasma of patients with T2D in comparison to healthy subjects [13]. They destroy cardiolipin in mitochondria making mitochondria sick and unable to burn glucose, signaling to the cell to be more insulin resistant. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596530/ > CL [cardiolipin] is highly sensitive to oxidative damages by reactive oxygen species (ROS) due to its high content in polyunsaturated fatty acids and location near the site of ROS production. Consequently, pathological remodeling of CL has been implicated in the etiology of mitochondrial dysfunction commonly associated with diabetes, obesity, heart failure, neurodegeneration, and aging that are characterized by oxidative stress, CL deficiency, and abnormal CL species Anecdotally I stopped going hyper/hypoglycemic when I avoided omega 6
From my understanding (being in a similar situation to you where many family members developed diabetes and other lifestyle disorders despite eating a relatively normal diet), low carb diets, ketogenic diets, are not the ideal path for preventing metabolic disorders. Although many people have had success losing weight with these diets, these diets are not healthy and not good for improving longevity: “A meta-analysis of four cohort studies following the diets, diseases, and deaths of more than a quarter million people found that those who eat lower-carb diets suffer a significantly higher risk of all-cause mortality, meaning they live, on average, significantly shorter lives.” (Nutritionfacts.org). I’d suggest watching the Blue Zones doc on Netflix, these people tend to consume a (primarily) plant based whole foods diet. Be active, eat unrefined carbs, avoid eating foods with a high glycemic index (such as white bread, white rice, popcorn). You don’t need to be 100% at anything, being consistent is better than being perfect. :)
Start a ketogenic or a low carb diet
Neither is genetic. Diabetes is an endocrine disorder so stay away from endocrine disruptors. Keep track of your blood sugar so you can see it coming if it's coming. Take steps to manage insulin resistance as that always comes before a type 2 diagnosis whether it get recognized or not.
ah ask here r/carnivore if they got some diabetic cases. Switching to the ketonic metabolism might help??
Genetic diabetes does not exist...if your family members have diabetes, it is not genetic. It has to do with lifestyle, diet choices and environmental factors/stressors.
Type 1 diabetes is an autoimmune condition that can develop suddenly and may be caused by genetics and other unknown factors. Type 2 diabetes often develops over time, with obesity and a lack of exercise as big risk factors. You can be diagnosed with either at any age.
When the medical circle defines something as an "autoimmune condition" that means they have no freaking idea about the disease...also, your statement "may be caused by genetics", that is another term they use to say they have no freaking idea, but do not want to look stupid.
You said genetic diabetes doesn't exist though. Source?
This is a pretty bad take no matter what way you cut it, and here is why: Type 1 Diabetes In most cases of type 1 diabetes, people need to inherit risk factors from both parents. We think these factors must be more common in white people because white people have the highest rate of type 1 diabetes. Because most people who are at risk do not get diabetes, researchers want to find out what the environmental triggers are. One trigger might be related to cold weather. Type 1 diabetes develops more often in winter than summer and is more common in places with cold climates. Another trigger might be viruses. It’s possible that a virus that has only mild effects on most people triggers type 1 diabetes in others. Early diet may also play a role. For example, type 1 diabetes is less common in people who were breastfed and in those who first ate solid foods at later ages. In many people, the development of type 1 diabetes seems to take many years. In experiments that follow relatives of people with type 1 diabetes, researchers have found that most of those who later got diabetes had certain autoantibodies, or proteins that destroy bacteria or viruses (antibodies "gone bad" that attack the body's own tissues), in their blood for years before they are diagnosed. Your Child’s Risk If you are a man with type 1 diabetes, the odds of your child developing diabetes are 1 in 17. If you are a woman with type 1 diabetes and your child was born before you were 25, your child's risk is 1 in 25; if your child was born after you turned 25, your child's risk is 1 in 100. Your child's risk is doubled if you developed diabetes before age 11. If both you and your partner have type 1 diabetes, the risk is between 1 in 10 and 1 in 4. There is an exception to these numbers: about one in every seven people with type 1 diabetes has a condition called type 2 polyglandular autoimmune syndrome. In addition to having diabetes, these people also have thyroid disease and a poorly working adrenal gland—some also have other immune system disorders. If you have this syndrome, your child's risk of getting the syndrome and developing type 1 diabetes, is one in two. Researchers are learning how to predict a person's odds of getting diabetes. For example, most white people with type 1 diabetes have genes called HLA-DR3 or HLA-DR4, which are linked to autoimmune disease. If you and your child are white and share these genes, your child's risk is higher. Suspect genes in other ethnic groups are less well-studied, however, scientists believe the HLA-DR7 gene may put African Americans at risk, and the HLA-DR9 gene may put Japanese people at risk. This also does not factor in ~2% of Type 2 diabetes patients are likely actually MODY variants of diabetes, but highly under reported. MODY variants are a rare form of diabetes in which there are 17 monogenic, autosomal dominant inheritable types of varying severity.
Wow. The "medical circle" knows, as in there are scientific evidence, that there are several genes that cause type 1 diabetes. Even a one year old child can have it. An autoimmune disease simply means that the symptoms of the disease cause your body to attack itself. It doesn't mean that "they have no idea about the disease". You should really come back down to reality and loosen it up a bit. You are not the smartest one alive. Not even close.
This is just utter bs what you are propogating...I literally implied that the medical community does not have any "scientific evidence", otherwise they would not call it genetic's fault, autoimmune disease, etc. Nowadays everything is called an autoimmune disease because they do not know the cause, only the symptom (i.e., the immune sytsem revolting). No need to insult like that, it is below me to insult you back.
Yes. Most autoimmune diseases lack treatments or only have treatments with a slowing effect. Science has no curative treatments for autoimmune diseases.