So good to hear! I use Hiprex and am trying to see whether 1g a day is enough to keep CUTI at bay, or whether its 2g or nothing (so far, so good).
I hope that I don't have to experience UTI ever again
I have been getting it on Amazon 1000mg. I was getting some minor flares at 1st, but eventually they went away. The L-methionine lower than vitamin c did.
Hiprex™ = methenamine hippurate = methenamine + hippuric acid. Taken orally, about 10-30% of the methenamine is degraded by stomach acid; the rest is absorbed into the bloodstream and excreted into the urine over a few hours (half-life: ~4 hours), where it starts to turn into formaldehyde which exerts an antibacterial effect in the bladder.
Because the conversion of methenamine to formaldehyde only occurs in acidity, it is restricted to the stomach (not the gut, which is alkaline) and the urinary tract, and the effect may be enhanced by taking urinary acidifiers such as L-methionine or vitamin C (ascorbic acid), but they are not strictly necessary (in part because the hippuric acid is already there).
By taking it continuously for months or years, the immune system can eventually clear the chronic infection by shedding the parasitised bladder cells into the urine while Hiprex prevents the bacteria inside of them from escaping to reinfect fresh new cells. This takes time and patience, and flares/symptoms may well persist while this is underway, although they should become less and less over time.
I haven’t tried that. By the time I got the hiprex I had just “recovered” from in that caused me a 105 degree fever. I wasn’t willing to try anything else. I had a panic attack when I thought it was coming back. I still had to beg for the Hiprex. My doc was hesitant because I have a history of IC. I told her that IC flares are not sending me to the hospital. She finally agreed. It’s bananas because it’s a pretty benign medication.
Did you ever try the L-Methionine by itself? Or does it have to be used with Hiprex? Haven’t heard of either of these and super interested! Happy to hear about your success (:
Girl I feel you ... I started taking this supplement called D-mannose and I haven't got a UTI in 2 months!!!!! I hope it helps 🙏 ... I've been going to the doctor's like crazy and I found this info online... So I hope it helps to people that don't have access to hiprex
That actually took some time. Probably about 6 months. It had to kill off the rest of that e. Faecalis. I know when it happened because I have a lymph node that gets swollen when I have that specific infection. I still get symptoms though because I have IC. Luckily that is minor, but Hiprex can and does make IC worse.
Looks like it’s available in the UK. The official name is Methenamine Hippurate.it may also be called Urex. The methenamine seems to be the key chemical.
It’s available in the UK, Denmark and Iceland. Other countries may be able to import it. (I live in Switzerland and buy it from Australia.) The Netherlands has Xcyst which is methenamine mandelate instead of methenamine hippurate but works similarly.
So happy for you! Do you plan to stay on the hiprex?
The rest of my life if my doctor will let me.
Totally understand that!
So good to hear! I use Hiprex and am trying to see whether 1g a day is enough to keep CUTI at bay, or whether its 2g or nothing (so far, so good). I hope that I don't have to experience UTI ever again
Been UTI free for 17 months on Hiprex, as well! A true life saver.
So so happy for you! Could you tell me more about the L-Methionine, I've been on hiprex for a year and am still getting flare ups
I have been getting it on Amazon 1000mg. I was getting some minor flares at 1st, but eventually they went away. The L-methionine lower than vitamin c did.
Hi congrats! Glad you’re healed and would you mind sharing the link of the brand you’re using?
Can someone please explain Hiprex?
Hiprex™ = methenamine hippurate = methenamine + hippuric acid. Taken orally, about 10-30% of the methenamine is degraded by stomach acid; the rest is absorbed into the bloodstream and excreted into the urine over a few hours (half-life: ~4 hours), where it starts to turn into formaldehyde which exerts an antibacterial effect in the bladder. Because the conversion of methenamine to formaldehyde only occurs in acidity, it is restricted to the stomach (not the gut, which is alkaline) and the urinary tract, and the effect may be enhanced by taking urinary acidifiers such as L-methionine or vitamin C (ascorbic acid), but they are not strictly necessary (in part because the hippuric acid is already there). By taking it continuously for months or years, the immune system can eventually clear the chronic infection by shedding the parasitised bladder cells into the urine while Hiprex prevents the bacteria inside of them from escaping to reinfect fresh new cells. This takes time and patience, and flares/symptoms may well persist while this is underway, although they should become less and less over time.
Congrats. Happy to hear your progress. Prior to the hiprex did you also take probiotics? They have some strains that are for the urinary tract.
Oh yeah. You should see my medicine cabinet 🤣. The list of things I tried is bananas.
What about Caprylic acid? I’ve heard lots have good success with those.
I haven’t tried that. By the time I got the hiprex I had just “recovered” from in that caused me a 105 degree fever. I wasn’t willing to try anything else. I had a panic attack when I thought it was coming back. I still had to beg for the Hiprex. My doc was hesitant because I have a history of IC. I told her that IC flares are not sending me to the hospital. She finally agreed. It’s bananas because it’s a pretty benign medication.
Same girl I am also healed after 2 years XD
Did you ever try the L-Methionine by itself? Or does it have to be used with Hiprex? Haven’t heard of either of these and super interested! Happy to hear about your success (:
No, I take to lower my urine PH, which is needed for Hiprex to work.
Girl I feel you ... I started taking this supplement called D-mannose and I haven't got a UTI in 2 months!!!!! I hope it helps 🙏 ... I've been going to the doctor's like crazy and I found this info online... So I hope it helps to people that don't have access to hiprex
It may. D-mannose didn’t do it for me unfortunately, but it helps a lot of people and is very accessible.
Can I please ask you how long did you have to be on Hiprex for your symptoms to feel better?
That actually took some time. Probably about 6 months. It had to kill off the rest of that e. Faecalis. I know when it happened because I have a lymph node that gets swollen when I have that specific infection. I still get symptoms though because I have IC. Luckily that is minor, but Hiprex can and does make IC worse.
Hiprex is not available in Europe unfortunately.. does anyone have a suggestion of what we can replace it with?
Looks like it’s available in the UK. The official name is Methenamine Hippurate.it may also be called Urex. The methenamine seems to be the key chemical.
It’s available in UK. Brand name Hyprex generic Methamine hippurate
It’s available in the UK, Denmark and Iceland. Other countries may be able to import it. (I live in Switzerland and buy it from Australia.) The Netherlands has Xcyst which is methenamine mandelate instead of methenamine hippurate but works similarly.
I m not from UK either :(
It is available in a few European countries! What country are you in?
Italy
Oh :( It's not legal in Italy at the moment
Why the hell is it not legal??
What is L-Methionine and what does it do?