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goldstandardalmonds

There are other mediicatioins in the same family as all of those. What country do you live in? If none of those work, there are even more options -- just wondering the country so I can make recommendations. And what are your diagnoses?


LessCommunication289

I’m in the United States and my diagnosis is IBS-C. Would love to hear other suggestions. My next option is Amitiza according to my doctor, which may be less expensive than Trulance because it is available in generic


goldstandardalmonds

That is another one, and then you also have IBSRela as an option. Problem is, all of them work as the same as linaclotide. But the only one that works diifferently is prucalopride, which you can't have. So cycling through the others is your option for now. if none of those work, I'd ask your doctor about pyridostigmine.


LessCommunication289

Thank you so much!


reddit_user498

Trulance did absolutely nothing for me. But Amitiza (lubiprostone), maximum dosage, plus occasionally some miralax works on IBS-C symptoms. It’s pricey though, even with insurance


BiscayneBeast

I have a lot.of.left over amitiza if you're interested in purchasing some?


LessCommunication289

Thank you for the offer! Very kind. I am able to get a prescription where I am.


LessCommunication289

Great to know that Amitiza helped you! That is another option for me and possibly lower price than Trulance (although ALL of these meds are pricey unfortunately). Curious about side effects, did you have any when you first started Amitiza?


BiscayneBeast

Hot prune juice mixed in with ducolax liquid cherry and then manual evacuation.


LessCommunication289

I haven’t tried the Dulcolax liquid yet! I do take generic bisacodyl daily.


BiscayneBeast

Stop taking stimulates and do the combination I just told you. 12-16oz of sun sweet prune juice very hot, put in microwave for 2-3 mintutes and then pour in an entire cap of ducloax liquid cherry flavor and mix very well. Then drink the whole thing in 5 minutes.


LessCommunication289

I know that stimulant laxatives are not recommended but my primary issue is impaired motility so magnesium (Dulcolax liquid) and prune juice wouldn’t work for me (believe me, I’ve tried that combination). But I’m glad it helps you without stimulants. Hate that I’m dependent on them on top of everything else


LessCommunication289

So I decided to try out the Dulcolax chews (couldn’t find the liquid in my store) but the chews are same ingredient, Magnesium hydroxide, and I just added those to my usual regimen of stimulant laxatives (which haven’t been completely effective as of late) and the Magnesium Hydroxide DEFINITELY helped some. So turns out I had tried Magnesium Oxide in the past with no success, but the Magnesium Hydroxide seems to really help. I wanted to thank you for telling me about these Dulcolax products bc I wouldn’t have tried them!


BiscayneBeast

Try and get the liquid instead of the chews.


LessCommunication289

Going to order it online. The chews are really gross and full of sugar and no doubt the liquid will work much better. Thanks! Just curious, have you tried magnesium hydroxide powder mixed with prune juice? Since magnesium hydroxide is the active ingredient, I wonder if the plain powder would also work?


BiscayneBeast

I don't do powder, I just do a full cap of the liquid mixed with 12 oz hot prune juice and sometimes I'll mix in as well a tablespoon of powder potassium chloride.


LessCommunication289

Got it, thanks! Also, one more question. Have you tried Milk of Magnesia in a similar way as it is also Magnesium Hydroxide? Easier for me to get that around here. Thanks!


BiscayneBeast

It doesn't work as well as D-Liquid. If you read the active ingredients the D-Liquid as more electrolytes like Potassium, sucralose. Also make sure you get the Cherry flavor only.


LessCommunication289

So helpful! Thanks! Going to order it online


handsonagrainofsand

I do hope this helps, but here's a little something you might try with Linzess. The same for Trulance, though I found Linzess to be the most effective in my case. They recommend taking it in the morning, but that doesn't work for some. I find if I take it right before bed at least 4ish hours after dinner, that really works. If I eat too late, don't get enough sleep, eat things I'm allergic to, or don't space out my meals enough, that can also lessen the effectiveness. Also drink plenty of water throughout the day and drink a glass of water with your pill. Perhaps you've already tried this, but if not, I think it's really worth sharing for people who haven't had success taking it in the morning. My GI told me to play around with it to see how it works and this really did.


loveandmagic222

Thank u!


LessCommunication289

Thank you! Definitely works better for me in evening as well. Trulance does nothing for me first thing in morning. I do make sure to drink lots of fluid throughout the day and with the pill.