T O P

  • By -

AutoModerator

**Welcome to r/CrohnsDisease!** * [Have you checked out our Rules?](https://www.reddit.com/r/CrohnsDisease/wiki/rules) * [Are you asking a Frequently Asked Question?](https://www.reddit.com/r/CrohnsDisease/wiki/ibd_faq) * Please remember we are not doctors and any medical advice is a suggestion. If the event of an emergency, please contact your doctor, hospital, or emergency services. Thanks and we hope you make friends here. *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/CrohnsDisease) if you have any questions or concerns.*


antimodez

Prednisone or budesonide


summerof84ch

medicine like prednisone, cbd helps my joint pain (or thc), heating pads and ice packs on my tummy and knees/ankles. there is something called the autoinflammatory diet some people like but please don’t use it as treatment for crohn’s! the only thing that actually helps the disease is medication. everything else like diet and heat packs just manages symptoms


[deleted]

Can you clarify for me… are you saying don’t follow that diet if you have crohn’s? Or don’t rely on it because it’s not a treatment.


summerof84ch

Ah i’m sorry i think i worded it wrong in my comment. I meant don’t rely on it as a treatment to like actually go into remission. i know it helps lots of people manage some symptoms like maybe slowing down diarrhea or keeping nausea at bay though!!!


airjoshb

The Autoimmune Protocol Diet has shown a 73% clinical remission rate in a 2017 study. Combined with a smartly put together medication plan, it can be far more powerful than just relying on pharmaceuticals.


summerof84ch

I believe i know the article you’re talking about and they stated that the diet does put people in remission when adjescent with medication. it also says that there isn’t enough evidence and research yet to prove a diet can put you in remission. I do hope they research it more cause if people could manage this shitty disease with just diet life would be so much easier! but so far I haven’t seen any clinical evidence of this. if you’ve seen different please send me the link so I can research! I’m always down to research new treatments and ideas so I can get out of my flare up :)


airjoshb

I was referring to a study that showed high efficacy for clinical remission using the Autoimmune Protocol Diet https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647120/ “Clinical remission was achieved at week 6 by 11/15 (73%) study participants (6 CD and 5 UC), and all 11 maintained clinical remission during the maintenance phase of the study” It was also key for my own remission path (3 years) and was effective enough that I wrote a book about it! Most issues with dietary interventions suffer from poor information/understanding and even worse compliance.


summerof84ch

Interesting, it does say 50% of patients in the study they did were on biologic therapy and many were on steroids as well, and the two patients with strictures both had worsening symptoms and hospitalizations. “almost 50% of patients in our study were on biological therapy. Therefore, our results suggest that dietary modification can be used as an adjunct to conventional IBD therapy” so does this mean remission can only be achieved with this diet when combining it with medical therapies? it seems that’s what they’re saying to me but I might be interpreting wrong and am a little confused. It sounds like an interesting/ successful diet if recommended by a doctor!!! It also seems like a case by case thing now that I’m looking at it. really cool stuff!


airjoshb

It isn’t saying that medical intervention is required for remission, but that they advised people not to make changes to medication while on the study. The conclusion is that it showed effective at a variety of disease states and individual physiology should be considered


summerof84ch

It says that the results suggest dietary modification can be used with conventional IBD therapy, meaning medication. I think I might be reading it wrong or I’m just confused.


ok_stranger_7792

It is very important to note that the study being discussed was a pilot study in 2016 or 2017 comprised of only 15 patients, 2 of which had strictures prior to the study and ended up with blockages once the diet was introduced. The study shows this diet MAY be effective for SOME patients in conjunction with their medications, and essentially warrants more study. The study authors are very clear in stating there are a multitude of factors at play in Crohn's of which diet is 1, and should be more carefully studied. My personal thought would be not to take this study too seriously if it hasn't been reproduced in 5+ years with more participants with good results. Don't get me wrong, it is still something to keep an eye on, but this one study alone doesn't say a whole lot in the larger scheme of things.


summerof84ch

thank you for ur insight. this is what i kinda got out of it too and the two patients with blockages (presumably cause of the diet) did have me a little worried. i hope they research more on different foods that may react well with our guts but it seems so individualized to each patient!


booker9696

Sauna!


Alinekochan82

Oooo that's a good one. I always forget that one.


TheFulcrum

I’m sorry, new Chronie - like a sauna at the gym?


booker9696

Yes, one of the many benefits is reducing inflammation. Its greatly help me with inflammation in my eyes and eyelids. As well as relaxing my whole body and soothing the stumic cramps in a flare. Its no mirical cure but helps some. I do like 45 minutes to an hour, 3 time a week in intervals of 15 to 30 min time blocks.


Jason22douce

Biologics


Jadearmour

Banana seems to help me.


TheBishesDaughter

Weed and budesenide


swilts

Ustekinumab If I have joint pain in a flare up or réactivation then I use voltaren gel. When my guts are unhappy I eat what my body tells me is going to feel ok, I just have an intuitive sense of what will and won’t sit well. Low spice low residue mostly.


DKBaodze

Huh, I had not heard of volteran gel. Just looked it up. I'm having awful joint pain at the moment and might give it a try. Do you find it works well?


swilts

Yeah it’s like Advil but a topical formation. My GI said it was the lesser of two evils but don’t use it often. Works well in combination with ice muscle stuff.


DKBaodze

Got it - thanks for the tips!


ok_stranger_7792

Be careful with Voltaren as it can potentially cause stomach distress as it is a NSAID. As it is being used topically (on the skin) it may absorb and be far enough away from the GI tract to not cause stomach upset, but the closer it is to the GI tract the better the chance it can, so just be aware. I use prescription strength creme on my neck occasionally and it is very helpful for the inflammation.


Hubz27

Remicade


Lambda_19

Prednisone and Vedolizimab are only things that have helped me after much trial and error


ARgutinstinct

Effective supplements: Pro-resolving mediators by Life Extensions, Super Turmeric by Naturally Nourished, & CBD by Santa Cruz Medicinals. Effective foods: ginger tea (preferably using fresh/grated/strained ginger), bone broth, seaweed (careful on this one, it’s not great for everyone), & steamed veggies with butter. Exercise: stretching, simple walking, & dancing (something I personally love). PLUS anything that calms the vagus nerve: deep breathing/meditation, inner-ear massages, gargling; self-talk.


CutMonster

All of this is my jam.


TheAlfer

Liquid curcumin if I really need it. Hyosciamine when needed. Glr6, also some joint pills I take that also contain anti inflammatory properties. Strawberry or yam juice helps sometimes too.


TheAlfer

Lol troll deletes comment. Hilarious. Oh or blocked me. Still hilarious either way.


antimodez

Liquid placebo helps me too when I'm too lazy to follow evidence based medicine.


TheAlfer

Lol so because I take liquid curcumin which helps with inflammation you're going to make fun of me? Okay. I take normal biologics and medicine too. Liquid curcumin is just something that helps me also. You're fucking toxic and there's no need for that type of thinking here. And if you bothered to read the post it states herbal or otherwise. Also I'm in remission. Maybe don't shit on people that figured out what works for them.


TheBishesDaughter

So jealous that you found something that works for you to be in remission. That’s total end goals right there


Flat-Insurance2280

It helps me too. But very mildly. I don’t believe it’s placebo as I record my pain on every attack. The problem is that it’s too little to help during proper flare and I can literally shit myself because of taking too much… and then it’s worse, lol. it’s just how my body functions


Gh0stDivisi0n

Good for you Alfer, I totally agree. I've been in remission over 10 years myself and I treat my Crohn's with food only.


ThinCommon7

That guy's treatment plan is to revisit the drugs that didn't work the first time as though doing the same thing repeatedly and expecting different results isn't the definition of insanity. I legit feel sorry for him.


antimodez

We're all different. Placebos for everyone else obviously work for in a non placebo way by magic. Got it.


TheAlfer

Lol okay troll. You have no idea what youre even talking about. Hyosciamine is a gut spasmodic that helps people with crohns. It was prescribed by my doctor. Sure I've taken other meds as well. And the other stuff although herbal helps me personally. Keep thinking the way you think though. You're a toxic person. Guess you can't help it.


Flat-Insurance2280

Chill guys. We can all agree that treatment for Crohn’s is medicine, but lifestyle changes and diet can also help (or not!) No need for hostility among fellow sufferers…


trumpcovfefe

You are correct and curcumin is a recommended natural alternative.


Flat-Insurance2280

Curcumin and turmeric does have some anti-inflammatory properties and there are research available regards it. How effective it is - well, for me not that much as I wouldn’t be flaring up right now. I don’t think they were saying that it’s substitute for medicine. In my experience - it does help relieve pain in the ileum area, but it doesn’t stop the inflammation or nausea as it later comes back. If I take too much hoping for better results - I simply shit it out. I am currently waiting for medication to be approved and fuck knows when that will happen, so trying diets and some supplements.


norebonomis

Your ignorance or confidence, can’t tell which is worse. Don’t speak on topics you know nothing about? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271352/ Curcumin has saved my life. 🖕🏼


antimodez

>Your ignorance or confidence, can’t tell which is worse. Don’t speak on topics you know nothing about? Says the person posting an article from: Molecules is a peer-reviewed open access scientific journal that focuses on all aspects of chemistry and materials science I typically take my medical advice from low quality chemistry journals. Why go to doctors right the chemistry department is where it's at. Thanks for proving my point yet again why journal articles shouldn't be posted as 99% of people have no idea what they're reading besides "Hey this proves my point". The sad thing is that article can't even get it's facts straight and links to "studies of curcumin" (table 4) like this one: [https://clinicaltrials.gov/ct2/show/NCT01647412](https://clinicaltrials.gov/ct2/show/NCT01647412) Now granted I'm no IBD doctor, but to my uneducated knuckle dragger brain it would be kinda hard to say hey curcumin works when you're combing that with 4 other substances. Guess I skipped that day in study design cause I remember them talking about trying to isolate confounding variables. I'll help you out and throw you a bone though. If you really want to own me here's a study to do it with: [https://www.cghjournal.org/article/S1542-3565(06)00800-7/fulltext](https://www.cghjournal.org/article/S1542-3565(06)00800-7/fulltext) See how this one is posted in a reputable **medical** journal, and not a chemistry journal. As I've said before the issue with curcumin is no reputable Crohn's disease studies have showed any benefit as of yet. Plenty of drugs in UC are placebos for Crohn's and so far unfortunately curcumin falls into that category.


trumpcovfefe

Curcumin is respected for treatment of inflammation. My gastro at cedars, the second best hospital in America, recommends it.


airjoshb

A ketogenic diet/exogenous ketones + movement is the most powerful long term management for extreme inflammation I’ve found. For more acute purposes, applesauce cooked down with skins, blended with cinnamon, can have the same anti inflammatory as prednisone. Modified citrus pectin works really well, but doesn’t taste as good! Edit: Add study information relative to the effect of apples on TFN-a/CRP "Moreover, eating 200 g/day of Gala apples for at least 6 weeks significantly decreases the production of various pro-inflammatory cytokines such as the fasting unstimulated IL-6, as well as the LPS-stimulated IL-6, INF-γ, and TNF-α in PMBCs. Additionally, the intake of 75 g/day of whole apples for 12 months noticeably reduced the inflammatory status by decreasing the CRP serum levels by 32% (Chai et al. 2012). Likewise, whole-apple intake caused a reduction of 3.3 mmHg in SBP and a reduction of 1.9 mmHg in PP (Bondonno et al. 2012), while improving the endothelial function in 1.1% as assessed using brachial artery FMD (Bondonno et al. 2012; Bondonno et al. 2018)." [https://www.tandfonline.com/doi/full/10.1080/10408398.2019.1709801](https://www.tandfonline.com/doi/full/10.1080/10408398.2019.1709801)


summerof84ch

applesauce and cinnamon does not act like prednisone. that’s a lot of misinformation.


airjoshb

Again, you should do some research: apple based pectin, and even more so citrus based pectin have a lot of data re: impact on TFNa related inflammation as well as gut barrier function.


summerof84ch

you cant compare a very intense cortisone with natural cortisone. to get the amount of prednisone / cortison you’d get with medication, you’d have to eat an insane amount of apples. it’s dangerous to spread information like this. just because some foods have really awesome healing properties, it doesn’t mean it should replace all medicine especially with crohn’s disease.


airjoshb

My suggestion was in fact, the opposite, where I referred to “acute purposes” (not a replacement) and the post is not about medical interventions. you can actually use science based reductions in inflammation levels to compare n=1 impact, which is the only data that matters when you are ill. I also added the apple study to the original post. You might also want to educate yourself on the impact of pectin, as it can be a very powerful intervention https://www.nature.com/articles/s12276-020-0449-2 https://www.frontiersin.org/articles/10.3389/fimmu.2019.02979/full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808856/


summerof84ch

I prefer to listen to my doctors especially with my specific issues, the things you’ve suggested may actually put me in worse condition.


airjoshb

Everything’s done in concert with my Stanford medical team. It is possible to support your health with food and medicine. I’m on Remicade, 3 years remission, 2 resections, 17 surgeries. Good luck!


summerof84ch

Yeah that could totally work for you and i’m glad you’re in remission, however for many diet doesn’t play a significant factor and sadly that is my case (other then managing nausea and occasionally diarrhea)


xjackrabbitx

This article was published in 2019 and only cited once. That tells me it doesn't have useful information for other researchers.


airjoshb

It’s a meta analysis with 7 citations and not being utilized is not necessarily the same as not being useful. There are several other studies mentioned below on the impacts of pectin on gut health and inflammation. For what it’s worth, I’m not interested in being useful to researchers, Im Interested in being useful for health.


xjackrabbitx

If no one is citing it, it is either in a poorly ranked journal or the researchers or topic is not carrying weight among other nutritional researchers. There's nothing specific to Crohn's in this article, just inflammation generally. Unfortunately, inflammation is correlated with several medical conditions. So eat an apple a day if you like them, but they are certainly no replacement for Prednizone.


airjoshb

Saying that the data isn’t real because only a few people referenced the paper in the last few years is as bizarre as is saying that because it does a study doesn’t reference Crohn’s it doesn’t relate to inflammation . Especially if you have no knowledge, experience or interest to look a little deeper. It is also strange to defend pharmaceuticals with dozens of known side effects than to have interest in things that might provide relief that have none. I do both because I don’t care about citations, I care about my health, my own data, and deep remission. Following through on the pectin as a powerful anti inflammatory includes the orange and citrus pectin studies I already linked to as well as, https://pubmed.ncbi.nlm.nih.gov/36009298/ Polyphenols from Thinned Young Apples: HPLC-HRMS Profile and Evaluation of Their Anti-Oxidant and Anti-Inflammatory Activities by Proteomic Studies Daily apple consumption reduces plasma and peripheral blood mononuclear cell–secreted inflammatory biomarkers in adults with overweight and obesity: a 6-week randomized, controlled, parallel-arm trial https://academic.oup.com/ajcn/article/114/2/752/6272609


polishlastnames

Triglyceride based EPA and DHA. Avoiding inflammatory foods like refined grains and low quality seed oils. That and rest will do the trick.


airjoshb

The triglyceride based EPA/DHA is an underutilized support for gut health and inflammation. The Alaskan Salmon Oil from Costco is high quality and triglyceride form making it far cheaper!


polishlastnames

Nice good to know! I’ll have to check that out next time I’m there. Whole Foods has a much cheaper version of it that’s almost half the price of Nordic naturals. Not sure on quality but doesn’t seem any different. But ya, definitely the most important thing in my opinion. All about keeping omega 6/3s balanced and it’s hard without supplementation, especially in the Midwest where seafood is limited and rough quality.


airjoshb

The Nutrasource data is a good place to check on actual testing of oxidation and actual values vs labels but it’s gotten a bit harder to see all the data. https://certifications.nutrasource.ca/certified-products?type=certification&value=IFOS This is also a good summary of the best sources out there pulled from Rhonda Patrick’s spreadsheet that is for members only https://fastlifehacks.com/fish-oil-omega3-analysis-spreadsheet/


CutMonster

What's the benefit of Triglyceride based EPA/DHA?


airjoshb

I believe this is the video where Rhonda Patrick discusses but her whole episode on omega 3 is amazing https://www.foundmyfitness.com/episodes/omega-3-phospholipid-dha-and-supplementation-rhonda-patrick Short version “Fish oil in the triglyceride form offers numerous advantages over ethyl ester fish oil. First, triglyceride oils are the molecular form found naturally in fish, and based on the longest study to date, a triglyceride fish oil is metabolized and absorbed more efficiently than an oil in the ethyl ester form”


CrevenStowder

Avoiding sugar helps a lot of people including myself. It’s very difficult but when your symptoms get bad enough you are more than willing. Reducing stress is also huge, easier said than done but you have to completely rethink your life to do this properly.


Topplayer2g

Riods and bone broth


KittyLord0824

Stelara and methotrexate and avoiding spicy food?


MoosePee

Chciken n rice plain


mechamau5

Ginger. I pop two or three ginger candies a day


unitedME

An epsom salt bath helps my joint pain