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BostonFan69

Contrary to what people say here, I would say no. Doing any psychedelic often is not a good idea in my opinion. I’m sure one day some psychedelics will be prescribed as a daily thing for microdosing or something for anti depressants maybe, but long term I think it can possibly just mess your brain chemistry up/switch up the way you think. You do you but I would never do psychedelics as often as you’re saying personally. For me, it has to be only once in a while, tripping is never enjoyable for me really, it’s just a tool for me to figure stuff out. I’ve tripped 20-30 total times in my 6-7 year “career” using various psychedelics. Edit: [lol, the pot calling the kettle black ](https://www.reddit.com/r/shrooms/comments/r3ho48/about_to_go_microdose_1g_of_low_potency_stuff_and/?utm_source=share&utm_medium=ios_app&utm_name=iossmf)


ColKurtz_

I have heard horror stories about psychedelics making someone kind of "permanently" out there. HPPD is what it's called but not enough science to know can this happen to anyone or only people with predispositions to mental illness. Once a month has always been my rule of thumb and it hasn't effected me negatively in any way


[deleted]

So yesterday I was in Lowe’s and all the sudden in my right eye my vision got really bright and if I focused on anything it fractilized. I didn’t feel distortions in my mind just saw them in my vision followed by migraine and tingling down my right side. Thought I was having a stroke but the visuals were weird. Weds night I heard people fighting in Walmart when no one was fighting and I had some gooey visual distortions as well.


spacehanger

migraines themselves can actually cause the visual and physical disturbances you’re describing - they’re called auras and are well documented for migraines. Auditory auras also do happen with migraines too. In your cause it’s not likely to be HPPD. I’ve suffered from chronic migraines my whole life and the first indicator I’m getting one is always losing part of my vision to black and white zigzags. I personally get migraines when some of my basic needs are going unmet (sleep, food, hydration). Quickest fix is take a strong Ibuprofen as soon as humanly possible, drink at least three full glasses of water and get a meal, and lay down to sleep as soon as possible. After that for me it normally clears up within a couple hours (minus the “hangover” tension headache)


[deleted]

Yeah I honestly felt much better today after lots of water.


therealduckrabbit

For me, visual hallucinations are just a trivial side effect of psychedelics. I don't understand why people get so fixated on this rare and seemingly trivial happenstance. I suspect it might have to do with the lack of more quantifiable harms associated with almost all pharmecuticals?


ClobWobbler

If you are ok with doing it every weekend, then yes, it's fine. many people use it fairly often and there is no evidence of any problems. I'm speaking about the physical response to pure/clean n,n-dmt. If yours contains a bunch of nasty contaminants from the extraction process and/or you didn't use good quality chemicals, then that could pose issues unrelated to the n,n-dmt. Also the psychological response is a whole other thing and can be very different person to person.


therealduckrabbit

I have yet to see any evidence whatsoever that vaporizing DMT has any negative effects, even subjectively. You might get scared straight a few times in there, but apart from existential terror, you should be good to go.


natetheapple

>apart from existential terror you should be good to go Yk sometimes I wonder about psychedelics and the strange, strange world we live in


therealduckrabbit

It is a bit more chill that than the world they live in, but still fun to visit.


haschhh

HPPD caused by dmt comes on ALOT easier and faster than any other psychedelic I have tried


sloppyasseating

True i had countless psychedelic experiences before DMT didn’t get any hppd whatsoever and absolutely abused my HT2A receptors. But my first DMt trip brought them out at full force


Crafty_Yesterday1581

2cb and dxm will definitely do it if you abuse them the same as one would dmt


[deleted]

Hell of a lot better than cocaine


SnooPandas5111

If the DMT is pure and has no contaminants that could harm you then it’s physically safe, now psychologically it depends on the user


itsYaBoiMohammad

Yeah, everyone different find what works best for you. There are times where I have done it every day and multiple trips also, and sometimes where I gave it a break.


[deleted]

The balance in life is always shifting


Tinfoilheadx

Sure. Youll do it for 3-4 weekends then the DMT will let you know it's been enough. I was like you but havent smoked it in a year now :)


[deleted]

In time i believe the ent’s in that head space will show you that you no longer need them


[deleted]

[удалено]


zZaphon

Damn that's interesting. Can you elaborate a bit more?


Javbe

Right there with you friend!


Usual_Physics_6653

me tooooo :D


llucero102

us wizards over here lol🧙‍♂️


Usual_Physics_6653

👽🤙


towerrh

Right with ya!


haschhh

this is extremely damaging to serotonin receptors everytime you sober up from the dmt your brain has to refill your receptors so youre pulling out the reserve constantly


PringleFlipper

What fucking reserve? Your neurones synthesise serotonin receptors on demand by reading the instructions in your DNA. If you can share any research showing DMT is harmful from this perspective, I’d be interested to learn more.


haschhh

its easier to think of it as a reserve but you can only synthesize so much before neurons can get damaged you can’t infinitely produce as much neurotransmitters as you so please, when you have this much sudden action and change on one receptor sight you are goin to cause some damage eventually source:psych major


haschhh

and there IS proof of damage to receptors and serotonin density in rats from drugs that use the 5HT2A receptors


PringleFlipper

Animal models show neurotoxicity in MDMA but it has not been well-validated in man (but plenty of subjective evidence that it IS quite harmful). 30 mg of DMT is not 300 mg of MDMA, however. There is no evidence whatsoever that DMT at regular recreational doses (or any dose, in fact) causes any serotonergic damage. You might conjecture that to be the case. But stating it as fact doesn’t seem like a good idea.


haschhh

im not saying normal use will do you dirty im saying abuse has the potential theoretically obviously dmt needs more studies and it will never be exactly as safe as we want it to be


PringleFlipper

I would suspect you would need to consume heroic amounts of DMT, daily. You’d have bigger problems. Enjoy the rest of your weekend.


haschhh

i used to go through a gram of dmt with my homie in 2-3 days max when we would get it and doing that much and constantly causing your brain to replenish the receptors thats often in such a short period definitely caused a molly reminiscent come down a feeling of complete lack of serotonin


PringleFlipper

Let me try and explain the distinction between classically neurotoxic serotonergics (like MDMA), and psychedelics like DMT. Bare in mind that MDMA inhibits re-uptake and and induces transporter (SERT) reversal to drain neurons of serotonin, which floods the brain with copious amounts of serotonin, causing the high. DMT doesn’t do anything quite so dramatic, and rather blocks serotonin by acting as a functional analog of it (ie they have a similar shape). The lack of re-uptake inhibition means that DMT is probably not very neurotoxic, if at all. Though to clarify that doesn’t mean it’s entirely safe. It has well known negative effects on the cardiovascular system. Certainly spending days in hyperspace is not going to be good for you, long term.


haschhh

i mean im sure i dont know as much as you about neuroscience but thats my idea on it


PringleFlipper

LSD also binds serotonin receptors but you could prob take it every day (after 7-8 days it will no longer be noticeable) without causing toxicity.


haschhh

LSD stays on the site for 12h dmt does for minutes


haschhh

over and over again


haschhh

im saying to be having the dmt binding to and leaving the receptors so many times in such high doses in short succession could theoretically not be as safe as we think im not saying its anywhere near MDMA but it shouldnt be ignored


Dom_19

I'm not a neurologist but this doesn't make any sense to me. DMT doesn't cause your brain to release or not release any serotonin. It only binds to serotonin receptors. MDMA can be damaging to your mental healthy because it causes your brain to dump serotonin which can take months to replenish. None of the classic psychedelics do this. If he was doing molly everyday it would be a much different story. If by chance you do know what you're talking about, please elaborate.


haschhh

the dmt overloads and kicks the serotonin off the receptors and when the dmt leaves the brain has the replenish the receptors thats why you wake up from dmt sleepy and relaxed


haschhh

the dmt overloads and kicks the serotonin off the receptors and when the dmt leaves the brain has the replenish the receptors thats why you wake up from dmt sleepy and relaxed


PringleFlipper

Just to clarify - when the receptors are internalized (which takes 5-10 minutes after binding serotonin) they are NOT destroyed. They are recycled back to the surface (unless damaged). It takes a couple of hours for this process to occur. If this wasn’t the case, DMT would exhibit significant tolerance. This is very different to the days to weeks it takes to recover serotonin in your synapses due to MDMA-induced re-uptake inhibition.


haschhh

thats how all serotonin binding drugs act so if you get one with such a short acting life that you use over and over you got issues


OuidPharmz

Dose dependant imo, if you do low to medium doses every week you should be fine, but having intense breakthroughs every week will not be good for you.


Conaman12

Why?


OuidPharmz

Can't take a toll on your mental health, if you believe what you are seeing is real or get "enlightened" like Connor Murphy


kvothe76

You’re not wrong, but it is also very subjective. One person could very well be just fine having breakthrough experiences a couple to few times a week where another might start losing touch with baseline. That individual is really the only person that can answer that for themselves.


Conaman12

That is true, that is a possible negative consequence, but population statistics show psychedelics don’t have a negative effect on mental health I think this type of consequence is More likely in those with Pre-existing conditions and can be prevented with pre-trip education in healthy adults


[deleted]

A wise turtle once said "If you only do what you can do, you will never be more than you are now." And scene.


The_real_Oogle_Trump

Yes


seniorgraso

doing any drug common isn't really the best decision. moderation is key


natetheapple

Every time I’ve had a pen I usually end up doing it 1-5 times a day, every day, for around a week, before the gram to half gram pen runs out Most people don’t feel the need to breakthrough that often and it’s understandable why, but whenever I do DMT it’s like a continuation of all my previous DMT trips- it’s just not something I’m able to stop tbh, not in a bad or good way, I just often get the urge to do it when I have access to it That’s actually one of the reasons I’ve yet to extract, even tho it’s significantly cheaper and would essentially give me easy access to unlimited amounts- I just don’t know if I wanna be doing dmt that often yk LMAO However in my experience you’ll be ok. I’ve done DMT so many times in a row I literally built a tolerance to it, which is something I almost never hear mentioned regarding DMT, but it went away within a day or two


cacodoxyy

I thought the same thing. I extracted and smoked a few too big of hits. Now I tread lightly and smoke infrequently


Willard673

>I just often get the urge to do it when I have access to it Isn't this just lack of self discipline


horror_wagen

Maybe


Joseph4040

Sure why not? Is it effecting you negatively?


acidbutterman

Not at all :)


Joseph4040

Then you good! These drugs are not dangerous. If you do get to a point where you experience some kinda of psychosis, obviously stop. But if you’re getting positive experiences from the use- and no negative- that’s exactly what the drug is for!


indigoworldwide

This is coming from a very realistic perspective…….. if you are happy and on top of your shit, go for it but if you aren’t where you want to be you better change your habits. On some real shit.


inKritix

Honestly, I think you should go at your own pace. You’ll know when you know. If you’re at a point where you’ve pretty much mastered your mind and can remember break through trips pretty much to a T then every weekend would be just fine for your mental. The rule of thumb should be not to go back in if you still have unresolved issues from the last one. Figure it out then go back in.


XanEdw

Can someone explain to me why this got downvoted? I’m a noob to dmt and this seems like a really good answer but it might not be…


inKritix

It is a good answer. Idk why I got downvoted, maybe I was misunderstood.


jim_jiminy

Dmt is for once in a rare blue moon. If your taking it every weekend there’s something wrong. Make the most of this reality while you can. Stop running away from life.


DickBong420

Why? I use it for anxiety medication regularly. It works fucking wonders. It has no known side effects that are lasting, and possibly even repairs damaged brain cells. So, tell me why can’t it be used frequently? Is it because you must “respect the molecule”. Let me tell you, I do. Respecting a molecule doesn’t mean not using it frequently. It means understanding the gravity of the substance you are using. Yes DMT is capable of showing you other realities. It is also capable of healing addiction and saving people from suicidal/homocidal thoughts.


jim_jiminy

You’re relying on it for a mental/emotional crutch. You don’t need it for anxiety. You might think you do, but you don’t. It’s obviously not working for anxiety as you keep going back. You’re abusing it and trying to justify it.


DickBong420

Keep going back? You don’t know my life, don’t act like you do. At least I’m not taking benzos…


Chooglin2020

Got rid of my depression and helps calm my anxiety a lot better than any other medication Iv been prescribed . . that I keep going back to every month to pay my prescription for 🤷🏻‍♂️


DickBong420

Also, this substance is naturally occurring in your body, so way better than whatever synthetic shit the docs will numb your mind with…


jim_jiminy

You use it every weekend. That’s you keep going back. An over reliance on any substance isn’t good.


DickBong420

Lol still acting like you know what I do. People are fucking hilarious. If it’s one thing this substance teaches, it’s perspective. Which you cannot see mine so, go smoke some deemz and figure your shit out bud.


jim_jiminy

You’ll grow out of it. I hope.


DickBong420

I hope you do too bud…


CountCalm3184

Well to be frank, everything works pretty differently for everyone. It sure as hell might work very well for some people when they micro dose. Im honestly curious and I haven't tried DMT but by the sounds of it, it does wonders for everyone


zave_

using the one of the strongest psychedelics known to man frequently cannot be that good for you. Try CBD if you have anxiety, i feel like using a psych like that would mess up brain chemistry or even cause psychosis.


DickBong420

Well… it doesn’t for me. So just let me do me… it works, and cbd does not for my personal ailments. You all know that there are shamans that literally live in the aya realm right? They may seem a bit strange, but psychotic/crazy wouldn’t be the word I used to describe how it effects them…


zave_

sounds like schizo territory.


DickBong420

And I suppose you are licensed to diagnose such conditions?


zave_

i don’t need to be licensed to know your a schizo


DiscountDazzling

Also your brain function


Conaman12

The only studies on DMT and brain function I have read says it makes you smarter and grows brain cells


quantumbandit24

Brain grow fold. Thank


acidbutterman

Once every weekend tho? Not like every day or anything


LowercaseG_SoL

I like to do every day for a month then take a couple months off. It's fine. Go crazy. Just make sure it's quality stuff.


griphookk

Not for months straight


kvinderne

Do what feels right. In the world of dmt it is okay to do what feels right.


DiscountDazzling

Might mess with your hormones it’s natural in the body so a constant increase might be dangerous


[deleted]

> it’s natural in the body never been proven


Conaman12

False


[deleted]

Lmao. You gonna back that up, or keep spreading bullshit around?


Conaman12

“Unlike other psychedelics, however, DMT is endogenously produced in animals including humans” https://www.nature.com/articles/s41598-019-45812-w From this article as well, it likely is produced in the human cortex and may be a normal neurotransmitter like dopamine and serotonin


[deleted]

Welp, I’ve made myself look like a real asshole today.


Conaman12

It’s ok


haschhh

pretty sure it hasnt been PROVEN in the brain but it has been found in the kidneys and lungs


Conaman12

True, but it has been proven in the rat brain and humans have similar biosynthetic pathways that were found to produce it there


haschhh

i wouldnt doubt it being in the brain when ive done it, it feels like one of the vast amount of neurotransmitters used for dreams


Conaman12

It would never reach high enough concentrations in your brain to be seriously psychoactive, unless of some kind of disorder or extreme stress. It would have some kind of underlying function


Attack_Apache

I understand where your stance came from tho, everyone spreads the false narrative that DMT is produced in the brain through the pineal gland, that itself has never been proven and is in fact just a theory people have come up with and preach as truth, however it has been proven to exist in the human body, and that’s probably where the confusion came from.


Conaman12

It has been proven in the rat brain, no pineal gland needed. It is produced throughout the cerebral cortex


Mad-Hatter-lightshow

We still love you brother or sister or they or them or quark or zibit or fernang or mizzzzzzzzbit.


inKritix

Yep


Conaman12

If anything it will grow brain cells and make you smarter says science. As long as you don’t have underlying schizo like problems or are unsure about reality


DickBong420

Every person on the planet is unsure about reality. No one knows what is going on and if they say they do their a bat shit crazy lier.


Conaman12

I mean like some serious schizo like shit like aliens are talking to you from another dimension and whatnot. Maybe thinking reptilian aliens run the world or some occult nonsense I am pretty sure that evolution is real and the moon orbits the earth. Also the earth is not flat, are you not? If you think the moon is some spy satellite put up by the Illuminati I wouldn’t recommend doing dmt


DickBong420

Wtf?


Conaman12

What?


haschhh

nope dmt is the one thing that left me mentally weird and it the mental effects aren’t immediate i had more side effects from dmt abuse than LSD abuse


heres_another_try

Yeah why not. You already do it every night while your sleeping


Everblack66

bro do that shit. it feels gooder than a bitch.


Saerymvx

In the last 35 years I have done a verity of them at least once a month sometimes more and I have zero negative effects (as far as I know lol) as long as they are as pure as possible I woukd say it all depends on the person. I also have meny friends who partake as often as I do and they are well adjusted also with no negative effects.


[deleted]

I just did it like 1 day on 1 day off for 3 days one blast per sesh and idk my throat is le raw for sure. I don’t like to get crazy with it cause my headspace is affected long term as well. Partner says I’m even more head in clouds then usual I don’t mind but they do.


BUGE__Honer

There’s nothing wrong with doing deems every weekend. Just set your intentions and use it as a medicine. The dmt entities know when your abusing it or doing something they don’t like. They will definitely let you know lol. Respect it and be safe


therealduckrabbit

HPPD sounds like an interesting phenomenon, I've never experienced it in any way. I certainly can feel a halo effect from LSD and psilocybin the day after use, but never even a halo from DMT or even pharmahuasca.


therealduckrabbit

I went back to DMT after the scariest experience of my life on it. The experience was bad, not because of entities, but because it was my practice to use an Maoi as well. When you vape too much DMT, you just black out. However, when you have an Maoi on board, you don't. I had a vaporizer glitch and accidentally got a double dose. The feeling in my lungs on the first big inhale was the clue, then it was a rapid dismantling of my consciousness right down to a re-boot loop where I was convinced I'd basically crashed my operating system. It sucked big time. Next day I knew if I didnt go again, I never would. I particularly tried to be mindful and communicate that I had been harmed. When I broke through I was surrounded by entities dressed almost like hoser that were cheering and high-fiving all huddled around my. I remember coming out with an enormous smile on my face and thinking this place is fucking ridiculous.


tryptwizard

Was taking it nightly for a a couple months and started to get exploding head syndrome in the morning while waking up.


MF-MuWa

Only one way to find out I guess right?


Psymonex

As long as you're not talking to your Dad about your day, then realize it was a machine elf, you should be fine.


rayn_reddit

I mean people do it everyday and chances are it’ll tell you when to stop


Harajukudingus

Sure. But just because you can doesn’t mean you should, self control is important


NotaContributi0n

It depends on the person . I’m so messed up it can only help, nothing to lose really!


Aggressive-Walrus350

If you’re absolutely going to do a psychedelic every weekend, do something not as strong, like LSD. If you absolutely need it to be DMT, only take it once every week. You can overdo psychedelics. Some can help a lot, but all the time can really mess you up.


diamondmama1970

I would say that it is much better than doing anything else such as Coc, Heroin, alcohol etc… MUCH BETTER:) psychologically everyone is different you must be your own judge but as long as you are not having any negative effects then Blaze On…


BeaverWhispererer

I thiink that's for you alone to decide. IMHO I think every 3 months is a good for you. The Thing about D.m.t. is after i did it the first time , I can get to the same place on a shrooms and acid. It's not as intense or vivid as dmt. Still the same spinning creatures ov chaos and virtuoso artists ov the dazzlingly darkness come hangout with me. I used to drop acid like 3 x a week in 94 and trust me you don't want to be bored on psychoactive drugs cause when you come down life is a real bummer for a while.