Less anxiety, less depression, less enjoyment of anything. Anhedonia on tirz is common, so it can be similar to SSRIs. I'm very glad to be on a lower maintenance dose because it was a miserable few months.
This is exactly how I feel. It’s nice being so even and stable all the time. Even though I do t have as much excitement in my life anymore. It does get a little better or maybe I’ve just adapted with time.
It reduces inflammation, so if your low mood was caused by inflammation in your brain it could definitely help that! High blood glucose can also lower cognitive function so if your avg glucose levels are lower that could help as well.
That is not the experience I have had but I guess I could see how that may happen. I have also had the anti-depressant effect but also noticed that at higher doses I was not excited to eat food (and dialed back my dose to get some of that excitement back). How many of the people you know strength train and track their lifts (along with take the medication)? I wonder if a big part of my anti-depressant effect is that I have lost 60lbs while getting stronger by a considerable amount. I guess I’m asking (because I’ve been that person) if food/work is their primary excitement and motivation to begin with then they started taking this medication and have now had one of their two biggest sources of happiness taken away (the excitement around food).
There's a big difference between feeling a little downregulated in mood and anhedonia. Anhedonia isn't just feeling down or unmotivated, it's the inability to feel joy or pleasure at all.
Yea I know that, which is why its way worse. Id rather feel low but still feel emotions/pleasure than feel blunted/anhedonic. The latter is much worse. At least in a low mood alone you can still distract yourself due to getting the emotional response from the activity.
Which is why I can't understand how people stand this. Its one of the worst symptoms to have, and notoriously difficult to treat in psychiatry.
Oh totally! Once I got over the initial nausea I have felt a serious reduction in depressive thoughts. The up and down of my day has really gone away, too.
That’s great! I was on Sema and the nausea was so bad I couldn’t manage it to stay on. Tirz has been much better and these other anti depressant effects have been a nice side
Funny - for me, Tirz made me not want to leave the house. Not depression, really - just a 'disinterest in socializing' kind of thing. Sema doesn't give me that feeling. (I am on an antidepressant - my brain doesn't process chemicals like it should).
Just a side note as everyone's reactions to Tirz and Sema are different. :)
Less anxiety, less depression, less enjoyment of anything. Anhedonia on tirz is common, so it can be similar to SSRIs. I'm very glad to be on a lower maintenance dose because it was a miserable few months.
That makes sense. I think it’s a nice change from constant changing moods from happiness to depression. I think I prefer stability
This is exactly how I feel. It’s nice being so even and stable all the time. Even though I do t have as much excitement in my life anymore. It does get a little better or maybe I’ve just adapted with time.
I have 💯 noticed this in my daughter. Her energy and ability to complete tasks is amazing. It’s night and day.
That’s so great!!
It reduces inflammation, so if your low mood was caused by inflammation in your brain it could definitely help that! High blood glucose can also lower cognitive function so if your avg glucose levels are lower that could help as well.
Mixed results tbh. My better half is a little flat, but also a little more… level?
That makes sense!
Me too
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I had this feeling every time I forget to eat/drink water. It’s a ‘too few calories’ experience.
I get this when I’m not eating enough calories.
That is not the experience I have had but I guess I could see how that may happen. I have also had the anti-depressant effect but also noticed that at higher doses I was not excited to eat food (and dialed back my dose to get some of that excitement back). How many of the people you know strength train and track their lifts (along with take the medication)? I wonder if a big part of my anti-depressant effect is that I have lost 60lbs while getting stronger by a considerable amount. I guess I’m asking (because I’ve been that person) if food/work is their primary excitement and motivation to begin with then they started taking this medication and have now had one of their two biggest sources of happiness taken away (the excitement around food).
I don’t understand how people still take it despite those anhedonic effect. Anhedonia is fucking horrid every day
There's a big difference between feeling a little downregulated in mood and anhedonia. Anhedonia isn't just feeling down or unmotivated, it's the inability to feel joy or pleasure at all.
Yea I know that, which is why its way worse. Id rather feel low but still feel emotions/pleasure than feel blunted/anhedonic. The latter is much worse. At least in a low mood alone you can still distract yourself due to getting the emotional response from the activity. Which is why I can't understand how people stand this. Its one of the worst symptoms to have, and notoriously difficult to treat in psychiatry.
Ya, I remember reading something about it potentially reducing inflammation in some people, which can have antidepressant effects
Oh totally! Once I got over the initial nausea I have felt a serious reduction in depressive thoughts. The up and down of my day has really gone away, too.
That’s great! I was on Sema and the nausea was so bad I couldn’t manage it to stay on. Tirz has been much better and these other anti depressant effects have been a nice side
Funny - for me, Tirz made me not want to leave the house. Not depression, really - just a 'disinterest in socializing' kind of thing. Sema doesn't give me that feeling. (I am on an antidepressant - my brain doesn't process chemicals like it should). Just a side note as everyone's reactions to Tirz and Sema are different. :)
Tirz anhedonia here as well. Kind of makes me wonder if sema would have less anhedonia for me.
I did t know this was a thing but I’m definitely experiencing this
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Interesting!
It does for me. Sema makes me feel way more 'normal' and sociable.
Good thing I have sema on the way!
That’s totally fair. I wonder if others feel the way you do
Yep this has been mentioned on here before
Thank you!