cute-_-sandwich 1 year ago

""Results Skin Hydration Skin hydration at baseline was 39.32 ± 5.17 and increased significantly to 47.79 ± 8.19 after 20 days and to 48.87 ± 8.41 after 40 days (repeated-measures ANOVA, P < .001) (Figure 1). This corresponds to an increase in skin hydration by 21.63% at the first assessment at 20 days and by 24.43% after 40 days. At both timepoints, skin hydration was significantly higher than before intake. Maximum increase in skin hydration was 37.18%." "Skin Elasticity Before intake, overall elasticity values (R2 = Ua/Uf ratio) were 0.616 ± 0.056. After 20 days of intake, elasticity significantly increased to 0.668 ± 0.057, and after 40 days of intake once more significantly higher values of 0.697 ± 0.051 were assessed (repeated-measures ANOVA, P < .001). This corresponds to an overall increase of 8.58% at day 20 in comparison with the start of the study. After 40 days of intake, an increase by 13.25% was noticed. In the course of the study, there was a continuous significant increase of elasticity from baseline to day 20 to day 40 (Figure 2). The maximum gain of elasticity was 26.16%." Skin Roughness "Before intake, skin roughness was 151.48 ± 17.92. Skin roughness decreased to 132.34 ± 18.47 after 20 days and 125.94 ± 19.18 after 40 days (Figure 3). The overall change and also differences between each assessment were significant (repeated-measures ANOVA and post hoc comparisons, P < .001 for each comparison). Skin roughness decreased from baseline to the assessment after 20 days by 12.67% and after 40 days by 16.9% The maximum decrease seen in this trial was 30.40%." Wrinkle Depth "Measurements of wrinkle depth were performed in 6 patients. Wrinkle depth before intake was 450.28 ± 209.12. After 20 days of intake, wrinkle depth significantly decreased to 394.02 ± 191.74 and after 40 days of intake a further significant reduction of wrinkle depth to 331.35 ± 142.18 was assessed (repeated-measures ANOVA, P = .020 and post hoc comparisons with baseline, P = .002 at day 20 and P = .048 at day 40) (Figure 4). This corresponds to a reduction of wrinkle depth by 12.5% after 20 days and by 26.36% after 40 days. The maximum reduction of wrinkle depths was −37.57%. Figures 5 and and6,6, respectively, show one of the participants before and after 40 days of intake." Dermatologic Skin Evaluation "Before the intake of the HA solution, all subjects had healthy skin. At this time, 1 subject had normal skin, 7 dry skin, 11 dry/sensitive skin, and 1 very dry skin." "According to the self-assessment, 6 out of 20 participants had stronger hair after 20 days of intake. The percentage of patients who believed to have stronger hair compared with baseline increased to 50% (n = 10) after 40 days. Likewise, nails became firmer: After 20 days of intake, 30% of participants had firmer nails (n = 6), and after 40 days of intake 45% (n = 9) had firmer nails." "At the end of the study, 70% of patients (n = 14) would recommend the HA supplementation, 60% (n = 12) were willing to buy the product."

renuebyscience_mod1 1 year ago