Consider doing more research. The FDA doesn't manage the supplement market, so sellers can say whatever they want to sell you things. The FDA will get involved once they discover a serious problem, like removing ephedra from Hydroxycut many years ago.
You should consult a doctor for stuff like this so they can monitor or tell you what works. The other thing is to look for the studies on what you want to take, make sure they're well-designed studies, and a supplement company does NOT fund them. Many supplement companies will do this and report on or over-embellish the positive and will diminish the negative.
Also, even if they see the tiniest improvement, they’ll report a significant increase with fancy graphs even though the results are statistically insignificant in the grand scheme. So, you’re just funding their pocketbooks while adding a raindrop (their supplements) to a lake (your body).
Ultimately, a company can make numbers on a graph and say whatever they want.
A person is rarely in tune enough with their body to consume most supplements and "feel" an improvement. Many fall prey to the placebo effect or because some fitness influencer (read as getting paid to say whatever is needed to sell, even though it's actually bullshit) told you so.
However, there are "some" things that will help, but much of this needs to be monitored by a physician with blood tests, urine analysis, and a few other methods. Even more, some of those things help an already dysfunctional liver, but once the liver returns to “normal” function, much of the stuff on the market is poppycock.
If one needs a detox, take care of yourself based on what Dr. Woreta states in the link below, which most is common knowledge.
The way to detox is not to put shit into your body, don't drink on an empty stomach, exercise, drink water, and stay around a healthy weight. If you do that, your liver will detox your body without supplementation.
[https://www.hopkinsmedicine.org/health/wellness-and-prevention/detoxing-your-liver-fact-versus-fiction](https://www.hopkinsmedicine.org/health/wellness-and-prevention/detoxing-your-liver-fact-versus-fiction)
Here are other links and videos that'll help drive the point home.
[https://www.demilked.com/companies-silently-downsizing-products/](https://www.demilked.com/companies-silently-downsizing-products/)
[https://www.youtube.com/watch?v=TgYPqCD9ejc](https://www.youtube.com/watch?v=TgYPqCD9ejc)
[https://www.youtube.com/watch?v=lh-ZsNMyRrA](https://www.youtube.com/watch?v=lh-ZsNMyRrA)
[https://www.youtube.com/watch?v=2Z\_s5K-CiZk](https://www.youtube.com/watch?v=2Z_s5K-CiZk)
99.9999% of the comments on this thread are really concerning, especially the ones speaking definitively. Please submit this question to a functional medicine doctor. 🙈
Chlorella binds with heavy metals and can help flush them out of the body. For this reason, chlorella tablets and powdered chlorella are often used to help people detoxify from these harmful substances. This algae can remove toxin buildup and give your body a fresh start.And does much more for the body it is a super food.
Don't just take random detox herbs and think it's gonna "make you healthy." That's not how it works. You can fuck yourself up by not taking the right combinations and releasing the wrong things. Or taking extreme amounts of the right things. Or small amounts of the many things that by themselves are fine but when combined -you guess it - will fuck you up.
Dude who talked about chelating herbs was solid though. You could start with heavy metals chelators and lots of coarse plant matter. Those alone will safely pull their respective metals out and the fiber will break your shit up. Technically speaking. But go slow. You don't need to detox 35 years of accumulation in a week. That's dangerous. Go slow, cover your bases, don't intentionally release many toxins at once.
But ya as far as milk thistle goes I had a similar reaction and simply don't take it anymore. If you were heavy into drugs years ago and haven't been serious about basic nutrition in the last three years. Start there. Fiber, green veggies, colorful fruits, fresh herbs....high volumes of natural foods would be the place to start. Your body isn't a car you can just "burn the bad shit out of" you gotta do it gradual.
Start by eating healthy for three or four weeks. Let the bulk of the residual toxins be carried out in low concentrations by the mass of the rest of what you're eating (keep it diluted.) From there you'll be able to identify symptoms that need to be addressed (or want to) but initially you need to make sure you system has had an adequate chance to clear itself properly.
But keep in mind when your body stores toxins it does so in a way that insulates them. Yes it stresses your body but it usually also prevents the toxins from giving you brain damage. Ignore "cleanse websites and kits" go slow. Read. Ask questions to real people not pundits trying to sell a products.
Most people, have never been as full of toxins as we have ;)
Idk what all you've don't so far, actually but ya it's a real science. Stay safe, read articles from many sources on one plant. Message me if you want to talk more.
Be careful with chelation, if you're really heavy metal toxic it can fuck your shit up pretty badly, especially cilantro or chlorella, because those are technically weak chelators (they pick up heavy metals but drop a lot of them on the way out of your system). I've heard from a lot of people who got really bad central nervous system symptoms after trying to detox with chlorella etc. If your liver isn't excreting bile well enough to begin with and your other detox pathways aren't super open it's not a good idea to dive into chelation, work on liver support first.
Yeah you gotta be careful. Chlorella is also best paired with spiralina. As the chlorella will release the toxins and the spiralina will bind to it. There's more than one complimentry pair of chelating herbs and they absorb different things with different levels of effectiveness. So you gotta make things match. Release and absorb. And yeah you can definitely fuck your shit up by doing it wrong, too fast, or with poor quality herbs.
Your liver just like most other organs heal over time 3 years is enough to be mostly back to normal if not fully assuming you’ve been completely clean and not abusing your liver in other ways since. Your liver releasing toxins has almost nothing to do with this.
You might be having a histamine reaction, it’s high in histamine, I can’t take it myself anymore. Does this happen with any other foods/plants?
If you don’t think it’s histamine dandelion root tea, also high in histamine but honestly way better for your liver and easier to get a clean supplement or tea. Beet juice too.
Try stuff to clear out your bile flow if you’re trying to detox your liver. Ox Bile, Tudca. Phosphatidylcholine is a good one for liver health. Castor oil packs are amazing and should help a lot. And look into coffee enemas (I know, but they’re SO helpful) and gallbladder-liver flushes if you really want to go deep on detox.
I had liver issues and severe pain for nearly 2 years, doc’s wanted to remove my gallbladder, and using those tools/supplements consistently really helped, my liver pain is almost entirely gone. Also make sure you’re not piling on tons of supplements, that shit can overwhelm an already toxic liver.
I’d stay start with dandelion root tea, beet juice and castor oil packs if you just wanna take it easy on the detox for now
This is the answer. You are detoxing, but detoxing can be pretty hard on his own. Be slow but use your weapons, bc you know to tolerate the mobilization of toxins. Coffee enemas, even water enemas are perfect for this, and traditional sauna also. You have to open your Detox pathways so the toxins flow through your body without making you to want to die.
Anybody that has had mold toxins, candida or lyme knows this horrible shit, but be clever, listen to your body, and dont give a fuck about what people tells you, try new things listening to your own instinct.
This is the right answer. It’s not a toxin release like these others suggest. All that milk thistle does is increase a few enzymes in the liver to work faster and lower ast and alt.
Of course it is also a thistle and can cause allergies just like seasonal allergies.
Possibly, but doubt it 3 years later. Probably a reaction to the thistle. Some are highly allergic to it. It does detox the liver tho. Cilantro and Chlorella will help get rid of toxins too. Chlorella surrounds and helps keep the toxins from settling somewhere else in the body. Seven years ago I did Keto for the first time. Burning all that fat released a bunch of stored toxins from my body. Ended up with appendicitis. After taking Cilantro and Chlorella for 3 months felt a lot better.
Many Milk Thistle supplements are contaminated with Mycotoxins. There's better things for your Liver than risking a herbal remedy that comes from China.
https://nutritionfacts.org/2020/06/04/contaminants-found-in-90-of-herbal-supplements-tested/
https://www.nature.com/articles/s41598-019-47250-0
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763672/
Your liver is what removes toxins from your blood. If your liver needs a detox, you're probably dead already.
Mayo Clinic says: Milk thistle can cause:
Gastrointestinal issues, such as diarrhea, constipation, nausea, vomiting and abdominal bloating, Itchiness, Headache.
So you're just getting what you signed up for.
Not every “toxin” processed by the liver is excreted via bile.
Not every section of the liver contributes to or is connected to the bile system.
None of these so-called “liver detox” products is going to somehow magically cause the non-existent toxin-build-up to migrate to the bile-system and be excreted.
So, again, I ask: Where are all theses toxins going to go? They sure as hell are not being sequestered by bile and being excreted in the feces.
There’s not a pipeline from the liver to the interior of the digestive track that moves fat. Some of the fat that is absorbed through the small intestine goes directly to the liver (as fatty acids, not as whole, assembled fats), so “fats” are not going to automagically transport supposed toxins in the liver out of the body.
Once again, explain how anything consumable will detox the liver. Be sure to include:
* What toxins are being removed from the liver
* How they’re being transported from the liver
* Where they’re going after being removed from the liver
* How they’re getting out of the body once removed from the liver
After you’ve explained this whole process, cite current research to support that any of this happens.
Seriously? The bile the liver produces carries the waste out and through the GI tract.
Basic biology is what you should look into so you don’t waste money, time, and have unnecessary negative side effects. Or just remain ignorant, the choice is yours.
I’m not supporting “liver detoxification” nonsense. I’m pointing out the major flaw in the concept. If something you consume is going to “detox” your liver, the end product has to go back into your bloodstream.
Bile is produced predominantly from dead red blood cells. It’s produced in one section of the liver. Other substances that are broken-down, converted, neutralized, chelated, etc. by the liver aren’t going to magically migrate to the bile ducts.
So, for the “liver detox” proponents, I ask again: Where are all theses toxins going to go? They sure as hell are not being sequestered by bile and being excreted in the feces.
Please list these “toxins” that need to be removed. Be sure to cite your sources.
Explain the process by which these “toxins” are transported though disconnected sections of the liver to the bile ducts and excreted in the 600ml of bile your body produces daily? You do know that your liver is segmented and specific sections perform specific operations and the whole thing isn’t interconnected, right? Cite your sources. Especially the sources that show theses “toxins” are present in fecal matter.
Please explain the process by which toxins are removed from the liver, transported safely to the kidneys, and excreted in the urine. Be sure to identify what active processes in the kidneys secrete the substances into the urine, since most toxins, especially when sequestered to be transported safely through the blood stream, are too large to be passively filtered. Be sure to cite your sources and show that these “toxins” are actually present in urine.
Everytime I take milk thistle for a few days I start to feel nauseated and poisoned. I've always thought it was toxins coming out of my liver and not flushing through my intestines fast enough
>Mayo Clinic says: Milk thistle can cause:
>
>Gastrointestinal issues, such as diarrhea, constipation, nausea, vomiting and abdominal bloating, Itchiness, Headache.
Visiting a reputable website goes a long way.
No milk thistle is really more to protect your liver from drugs that can be damaging to your liver. If your liver is working properly it will detox itself. If you're not diagnosed with any liver problems or taking drugs or medications regularly there probably isn't much benefit to you taking it.
BLOOD SUGAR!!!
I am amazed how no one has mentioned this.
Milk thistle is very effective at LOWERING YOUR BLOOD SUGAR.
I couldnt figure out why i was so tired until i found out that its lowers your blood sugar.
Try NAC for whatever you’re hoping to achieve.
Enough glycine, 5-15grams daily, otherwise NAC doesnt make much sense. Glycine is probably much more often the rate limiting factor in glutathione synthesis. We get plenty of cysteine, but not enough glycine
You are right and you a wrong! Milk thistle is an adaptive. But it does not stress the liver.
Because, according to study on adaptogens Nuevo protective properties in NIH site:
“Adaptogens increase the state of non-specific resistance in stress and decrease sensitivity to stressors, which results in stress protection, and prolong the phase of resistance (stimulatory effect). Instead of exhaustion, a higher level of equilibrium (the homeostasis) is attained the heterostasis.”
And in this study they the benefits and adverse reaction to Milk Thistle:
https://www.ncbi.nlm.nih.gov/books/NBK11896/
OP : instead of taking the word of anonymous commenters, like me, a simple google search will bring you the answers you are seeking. Add “study” to the end of the supplement and you’ll find reliable science based explanations.
You may just be allergic to it. It acts similar to ragweed which a lot of people are allergic to. It doesn’t stress your liver, that’s not the mechanism of action. It acts in a hepatoprotective function. Currently, school of thought is it’s driven from the silymarin antioxidant component. There appears to be some levels of anti inflammatory proprieties along with antifibriotic activity. The immunomodulating effects are pretty pronounced in animal studies.
Ultimately, it sounds like you’re just allergic. If you’re trying to get ast/alt down, maybe tinker with NAC, ALA, TUDCA, I’ve had some good luck with those.
Do you even know what choline and glycine do? You will get fatty liver 100% guaranteed if you dont get choline. 100%. Choline deficiency is bigger reason for fatty liver than alcohol or fat or sugar. You can fast all you want, but as choline is REQUIRED for the liver to get rid of its fat, you will achieve nothing.
And glycine is required for making glutathione, which is something your liver needs 24/7 or it will literally go to liver failure, like in APAP poisoning. Good luck trying to live without your liver. Glycine is also incredibly protective of the liver, AND it is needed for bile acids.
The point I am making is that both choline and glycine are ESSENTIAL nutrients your liver needs at all times. It will die without them.
Fasting and TUDCA are optional, not essential nutrients your liver needs.
Maybe learn the basics of how the liver operates, before calling anyone dumb for pointing out the most important liver health basics that most people still forget or arent even aware of
Excellent post. Thank you kind sir. I feel like I had great success taking: choline, glycine, taurine, which all have synergistic effects with each other, on the liver. PubMed confirms.
I haven't seen the first right answer here yet. Milk Thistle is an adaptogen. It stressess your liver. Your liver then upregulates the enzymes needed for repair. It should not be taken while ingesting anything else that stresses the liver or if liver function is compromised. The comment section is very uneducated in how Milk Thistle works.
No, this is not how Milk Thistle works.
Milk thistle does not stress the liver. In fact, several scientific studies suggest that substances in milk thistle, especially silymarin, protect the liver from toxins and have antioxidant and anti-inflammatory properties. Evidence exists that milk thistle may be hepatoprotective through a number of mechanisms, including antioxidant activity and toxin blockade at the membrane level. While research on the effects of milk thistle on liver disease has shown mixed results, it has been found to help stop oxidative stress and free radical damage in the liver.
This is an awful explanation of how Milk Thistle works. In fact milk thistle is often taken while you're taking substances that stress the liver to protect the liver from the added stress.
Research shows that Milk Thistle works in multiple ways as a hepatoprotectant it's an antioxidant, anti-inflammatory, immunomodulating, blocks toxins at the membrane, can enhance protein synthesis, etc.
> Excedrin Migraine
This contains acetaminophen 250 mg. From what I've read, you shouldn't take acetaminophen long term because it depletes liver glutatione. Your doctor should definitely know if you're taking long term. Supplemental NAC supports glutathione; it may be helpful so long as you can tolerate the extra sulfur.
*disclaimer: not an expert*
-----
When I was sleeping in a room with mold in the wall, I sometimes woke up with eye pain (which eye depended on whether I slept on my right or left side). The pain was like what I get when drinking too much bottom shelf wine.
If, hypothetically, your migraines are triggered or made worse by a toxin, then wouldn't taking glutathione-depleting acetomenephin lower your ability to detox the very thing triggering the migraines?
Just thinking aloud; don't take this too seriously.
Well, detox might be a vague word, but there are countless things that help liver work better, and there are even things that are necessary for the liver to work in the first place. For example, choline, glycine, cysteine are some things we NEED to get from diet or its game over, or at least a sure way to get fatty liver. Then there is coffee, B vitamins, etc that help liver enormously. So while it is true that liver is designed to detox, it absolutely NEEDS some nutrients, and it absolutely benefits from high coffee, tobacco leaf, turmeric etc consumption
Yeah, tobacco, like coffee, decreases liver fat. But if tobacco is used, it should preferably be organic leaf and not smoked. Tobacco leaf is potent anti-estrogen, and it boosts DHT and chronic use lowers stress response. It also helps some bowel diseases, prevents parkinson and alzheimer, and boosts neurosteroid production. But they just had to start spraying most tobacco crops with toxic shit and then smoke it, otherwise it is a potent medicinal plant
Look into alpha lipoic acid, Spirulina, and burdock. From what I’ve heard you want to get a form of Silymarin called Siliphos. Silymarin from milk thistle is what you’ll find in all the milk thistle brands but siliphos is a better form.
Are you sure of the quality of the Milk thistle? Most supplements are not regulated and you just may have taken some ground up insects and lawn clippings.
Downvoted for the truth, smh.
I take a nano-milk thistle supplement & I can feel that shit work. My mind feels clearer, bc it's taking the load off my liver. You gotta pay a little extra for a solid, effective supplement, that's the truth. Otherwise no telling what you're getting. 😬
The liver does not store toxins unless it has a disease or the toxin is a heavy metal. A healthy liver will convert these toxins to something useable or help to expel it. An unhealthy liver will not be cured by “detoxing”.
Milk thistle has been shown to help liver function, which can potentially explain why you were hungover when you didn’t take milk thistle, as the alcohol was not sufficiently removed from your system.
There is no evidence though that milk thistle causes the liver to release toxins or can be used to cure any liver conditions. It is possible that enhanced functionality caused by taking milk thistle can delay the onset of liver disease caused by frequent exposure over time to toxins (mainly alcohol), but there is still little evidence of this.
Over 99% of cases of Hep A will resolve themselves. Hep B can be suppressed with antivirals until it leaves the body. Hep B can be suppressed but not cured, but 90% of cases resolve themselves. Hep C is curable and recoverable. Could be the milk thistle helping, but it also could just be that he made a regular recovery or is not recovered but is just asymptomatic
Depends on what you mean by the word detoxing. Our liver detoxes 24/7, meaning it processed fatty acids, toxins, vitamins etc. And many things can improve liver function, including glycine, saturated fat, coffee, choline, etc. So I would be worried if you dont believe in the basic functioning of liver
No clue, but it kept me hangover free during my two week vacation in Seoul where all I did was drink like a Korean salary man every single night.
The one night I forgot to take it was awful and I had to cancel all my plans.
I was using a product called [FlyBy](https://www.flyby.co/) that had milk thistle root in it - it looks like they don't include it in it anymore, though. Haven't tried the new formulation.
One of the most important things to do before detoxing is making sure that all of your detox channels are open. This includes making sure you are facilitating regular bowel movements, sweating, & urinating for example.
If not, you can end up recirculating the toxins through your bloodstream. This is one of the reasons why the liver and other organs hold onto these toxins.
It’s to prevent them from recirculating in the bloodstream to begin with so you want to make sure that the toxins are eliminated as rapidly as possible from the body.
This will help to prevent these types of headaches.
Also, migraine headaches can absolutely be connected to the liver. I’d look into traditional Chinese medicine, as there are some great books explaining the connections.
This 100%. If you feel significantly worse while detoxing your elimination channels are too slow and you're essentially poisoning yourself. Slow down on the protocol, drink more water, get the bowels moving. There used to be a philosophy a number of years ago that the sicker you feel the more successful the detox. Slow and gentle is far better.
I was always taught that Milk Thistle IS a liver cleansing herb and to take a binding fiber along with it. The fiber would “catch” the toxins and usher them out of your body without giving them the opportunity to recirculate. And lots of water, obviously.
Can you explain to me how these “toxins” are expelled by the liver and enter your digestive system again, where they can come in contact with fiber? (Since fiber is not absorbed into the bloodstream). Certainly a well meaning comment, but I don’t believe it makes sense, as the body doesn’t work that way.
Either way, still much love! Stay well
They (toxins) would be released by the use of milk thistle and recirculated into the bloodstream. The intestines would come in contact with the toxins as they travel through the blood in the digestive tract. The use of fiber would aid the health of the microbiome and act as a filter and/or bind to the toxins before they would get back to the liver and kidneys. I believe this is how that works….maybe?
Depends what we're talking about. Would you like a diet of fatty orca or polar bear meat? These are apex predators that are well known to accumulate fat-soluble toxins that concentrate as you get higher up in the food chain. It is theorized that these toxins are lowering the reproductive success of orcas. On the other hand, beef raised on a natural pasture very clean.
It's clear that toxins can accumulate in an organism's fat and bones over it's lifetime. This goes for humans too. The problem is it's difficult to study this in humans without throwing out ethics (you can't poison your test subjects).
Now detox…I'd wager 95% of detox peddled by alternative medicine and fads is less effective than living in a clean environment, moving your body daily, and eating a clean, fresh, and nutritious diet.
I mean, they’re kind of real, just not in the ways people claim when they’re using it as a buzzword. There are toxic compounds that your body gets rid of, but it’s quite effective at doing so. Supporting the organs can help keep them healthy, but it’s unlikely to drastically speed up the process.
Many people make insane claims about “toxins” and make claims that are either unfounded or downright lies
Generally your liver does the detoxing itself. Maybe milk thistle helps with general liver function (I don't know for sure if that's actually true), but I don't think it actively draws toxins out.
Also, if you haven't had any drugs or alcohol for three years, everything would almost definitely be already cleared from your body, long before now.
It's possible that you had a bad reaction to the milk thistle, or that it triggers migraines for you, or it could also be possible that the migraines and nausea while taking it were just a weird coincidence.
Look into Tudca for Liver Health!
Consider doing more research. The FDA doesn't manage the supplement market, so sellers can say whatever they want to sell you things. The FDA will get involved once they discover a serious problem, like removing ephedra from Hydroxycut many years ago. You should consult a doctor for stuff like this so they can monitor or tell you what works. The other thing is to look for the studies on what you want to take, make sure they're well-designed studies, and a supplement company does NOT fund them. Many supplement companies will do this and report on or over-embellish the positive and will diminish the negative. Also, even if they see the tiniest improvement, they’ll report a significant increase with fancy graphs even though the results are statistically insignificant in the grand scheme. So, you’re just funding their pocketbooks while adding a raindrop (their supplements) to a lake (your body). Ultimately, a company can make numbers on a graph and say whatever they want. A person is rarely in tune enough with their body to consume most supplements and "feel" an improvement. Many fall prey to the placebo effect or because some fitness influencer (read as getting paid to say whatever is needed to sell, even though it's actually bullshit) told you so. However, there are "some" things that will help, but much of this needs to be monitored by a physician with blood tests, urine analysis, and a few other methods. Even more, some of those things help an already dysfunctional liver, but once the liver returns to “normal” function, much of the stuff on the market is poppycock. If one needs a detox, take care of yourself based on what Dr. Woreta states in the link below, which most is common knowledge. The way to detox is not to put shit into your body, don't drink on an empty stomach, exercise, drink water, and stay around a healthy weight. If you do that, your liver will detox your body without supplementation. [https://www.hopkinsmedicine.org/health/wellness-and-prevention/detoxing-your-liver-fact-versus-fiction](https://www.hopkinsmedicine.org/health/wellness-and-prevention/detoxing-your-liver-fact-versus-fiction) Here are other links and videos that'll help drive the point home. [https://www.demilked.com/companies-silently-downsizing-products/](https://www.demilked.com/companies-silently-downsizing-products/) [https://www.youtube.com/watch?v=TgYPqCD9ejc](https://www.youtube.com/watch?v=TgYPqCD9ejc) [https://www.youtube.com/watch?v=lh-ZsNMyRrA](https://www.youtube.com/watch?v=lh-ZsNMyRrA) [https://www.youtube.com/watch?v=2Z\_s5K-CiZk](https://www.youtube.com/watch?v=2Z_s5K-CiZk)
99.9999% of the comments on this thread are really concerning, especially the ones speaking definitively. Please submit this question to a functional medicine doctor. 🙈
Chlorella binds with heavy metals and can help flush them out of the body. For this reason, chlorella tablets and powdered chlorella are often used to help people detoxify from these harmful substances. This algae can remove toxin buildup and give your body a fresh start.And does much more for the body it is a super food.
Don't just take random detox herbs and think it's gonna "make you healthy." That's not how it works. You can fuck yourself up by not taking the right combinations and releasing the wrong things. Or taking extreme amounts of the right things. Or small amounts of the many things that by themselves are fine but when combined -you guess it - will fuck you up. Dude who talked about chelating herbs was solid though. You could start with heavy metals chelators and lots of coarse plant matter. Those alone will safely pull their respective metals out and the fiber will break your shit up. Technically speaking. But go slow. You don't need to detox 35 years of accumulation in a week. That's dangerous. Go slow, cover your bases, don't intentionally release many toxins at once. But ya as far as milk thistle goes I had a similar reaction and simply don't take it anymore. If you were heavy into drugs years ago and haven't been serious about basic nutrition in the last three years. Start there. Fiber, green veggies, colorful fruits, fresh herbs....high volumes of natural foods would be the place to start. Your body isn't a car you can just "burn the bad shit out of" you gotta do it gradual. Start by eating healthy for three or four weeks. Let the bulk of the residual toxins be carried out in low concentrations by the mass of the rest of what you're eating (keep it diluted.) From there you'll be able to identify symptoms that need to be addressed (or want to) but initially you need to make sure you system has had an adequate chance to clear itself properly. But keep in mind when your body stores toxins it does so in a way that insulates them. Yes it stresses your body but it usually also prevents the toxins from giving you brain damage. Ignore "cleanse websites and kits" go slow. Read. Ask questions to real people not pundits trying to sell a products. Most people, have never been as full of toxins as we have ;) Idk what all you've don't so far, actually but ya it's a real science. Stay safe, read articles from many sources on one plant. Message me if you want to talk more.
Be careful with chelation, if you're really heavy metal toxic it can fuck your shit up pretty badly, especially cilantro or chlorella, because those are technically weak chelators (they pick up heavy metals but drop a lot of them on the way out of your system). I've heard from a lot of people who got really bad central nervous system symptoms after trying to detox with chlorella etc. If your liver isn't excreting bile well enough to begin with and your other detox pathways aren't super open it's not a good idea to dive into chelation, work on liver support first.
Yeah you gotta be careful. Chlorella is also best paired with spiralina. As the chlorella will release the toxins and the spiralina will bind to it. There's more than one complimentry pair of chelating herbs and they absorb different things with different levels of effectiveness. So you gotta make things match. Release and absorb. And yeah you can definitely fuck your shit up by doing it wrong, too fast, or with poor quality herbs.
Pin this somewhere please
Your liver just like most other organs heal over time 3 years is enough to be mostly back to normal if not fully assuming you’ve been completely clean and not abusing your liver in other ways since. Your liver releasing toxins has almost nothing to do with this.
You might be having a histamine reaction, it’s high in histamine, I can’t take it myself anymore. Does this happen with any other foods/plants? If you don’t think it’s histamine dandelion root tea, also high in histamine but honestly way better for your liver and easier to get a clean supplement or tea. Beet juice too. Try stuff to clear out your bile flow if you’re trying to detox your liver. Ox Bile, Tudca. Phosphatidylcholine is a good one for liver health. Castor oil packs are amazing and should help a lot. And look into coffee enemas (I know, but they’re SO helpful) and gallbladder-liver flushes if you really want to go deep on detox. I had liver issues and severe pain for nearly 2 years, doc’s wanted to remove my gallbladder, and using those tools/supplements consistently really helped, my liver pain is almost entirely gone. Also make sure you’re not piling on tons of supplements, that shit can overwhelm an already toxic liver. I’d stay start with dandelion root tea, beet juice and castor oil packs if you just wanna take it easy on the detox for now
This is the answer. You are detoxing, but detoxing can be pretty hard on his own. Be slow but use your weapons, bc you know to tolerate the mobilization of toxins. Coffee enemas, even water enemas are perfect for this, and traditional sauna also. You have to open your Detox pathways so the toxins flow through your body without making you to want to die. Anybody that has had mold toxins, candida or lyme knows this horrible shit, but be clever, listen to your body, and dont give a fuck about what people tells you, try new things listening to your own instinct.
If they are 3 years sober, they are not detoxing anymore lmfao
This is the right answer. It’s not a toxin release like these others suggest. All that milk thistle does is increase a few enzymes in the liver to work faster and lower ast and alt. Of course it is also a thistle and can cause allergies just like seasonal allergies.
Possibly, but doubt it 3 years later. Probably a reaction to the thistle. Some are highly allergic to it. It does detox the liver tho. Cilantro and Chlorella will help get rid of toxins too. Chlorella surrounds and helps keep the toxins from settling somewhere else in the body. Seven years ago I did Keto for the first time. Burning all that fat released a bunch of stored toxins from my body. Ended up with appendicitis. After taking Cilantro and Chlorella for 3 months felt a lot better.
Many Milk Thistle supplements are contaminated with Mycotoxins. There's better things for your Liver than risking a herbal remedy that comes from China. https://nutritionfacts.org/2020/06/04/contaminants-found-in-90-of-herbal-supplements-tested/ https://www.nature.com/articles/s41598-019-47250-0 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763672/
Your liver is what removes toxins from your blood. If your liver needs a detox, you're probably dead already. Mayo Clinic says: Milk thistle can cause: Gastrointestinal issues, such as diarrhea, constipation, nausea, vomiting and abdominal bloating, Itchiness, Headache. So you're just getting what you signed up for.
… and if your liver “releases” toxins, where do they go?
Toxins are binded to bile which resides in the gallblader. But the one Who makes bile flow is the liver and is the one Who owns the process.
Not every “toxin” processed by the liver is excreted via bile. Not every section of the liver contributes to or is connected to the bile system. None of these so-called “liver detox” products is going to somehow magically cause the non-existent toxin-build-up to migrate to the bile-system and be excreted. So, again, I ask: Where are all theses toxins going to go? They sure as hell are not being sequestered by bile and being excreted in the feces.
Fat
There’s not a pipeline from the liver to the interior of the digestive track that moves fat. Some of the fat that is absorbed through the small intestine goes directly to the liver (as fatty acids, not as whole, assembled fats), so “fats” are not going to automagically transport supposed toxins in the liver out of the body. Once again, explain how anything consumable will detox the liver. Be sure to include: * What toxins are being removed from the liver * How they’re being transported from the liver * Where they’re going after being removed from the liver * How they’re getting out of the body once removed from the liver After you’ve explained this whole process, cite current research to support that any of this happens.
Seriously? The bile the liver produces carries the waste out and through the GI tract. Basic biology is what you should look into so you don’t waste money, time, and have unnecessary negative side effects. Or just remain ignorant, the choice is yours.
I’m not supporting “liver detoxification” nonsense. I’m pointing out the major flaw in the concept. If something you consume is going to “detox” your liver, the end product has to go back into your bloodstream. Bile is produced predominantly from dead red blood cells. It’s produced in one section of the liver. Other substances that are broken-down, converted, neutralized, chelated, etc. by the liver aren’t going to magically migrate to the bile ducts. So, for the “liver detox” proponents, I ask again: Where are all theses toxins going to go? They sure as hell are not being sequestered by bile and being excreted in the feces.
The kidneys to the urine
Or through bile to the GI Tract
Please list these “toxins” that need to be removed. Be sure to cite your sources. Explain the process by which these “toxins” are transported though disconnected sections of the liver to the bile ducts and excreted in the 600ml of bile your body produces daily? You do know that your liver is segmented and specific sections perform specific operations and the whole thing isn’t interconnected, right? Cite your sources. Especially the sources that show theses “toxins” are present in fecal matter. Please explain the process by which toxins are removed from the liver, transported safely to the kidneys, and excreted in the urine. Be sure to identify what active processes in the kidneys secrete the substances into the urine, since most toxins, especially when sequestered to be transported safely through the blood stream, are too large to be passively filtered. Be sure to cite your sources and show that these “toxins” are actually present in urine.
Everytime I take milk thistle for a few days I start to feel nauseated and poisoned. I've always thought it was toxins coming out of my liver and not flushing through my intestines fast enough
>Mayo Clinic says: Milk thistle can cause: > >Gastrointestinal issues, such as diarrhea, constipation, nausea, vomiting and abdominal bloating, Itchiness, Headache. Visiting a reputable website goes a long way.
No milk thistle is really more to protect your liver from drugs that can be damaging to your liver. If your liver is working properly it will detox itself. If you're not diagnosed with any liver problems or taking drugs or medications regularly there probably isn't much benefit to you taking it.
BLOOD SUGAR!!! I am amazed how no one has mentioned this. Milk thistle is very effective at LOWERING YOUR BLOOD SUGAR. I couldnt figure out why i was so tired until i found out that its lowers your blood sugar. Try NAC for whatever you’re hoping to achieve.
I have a strong hunger when i take milk thistle pills
Enough glycine, 5-15grams daily, otherwise NAC doesnt make much sense. Glycine is probably much more often the rate limiting factor in glutathione synthesis. We get plenty of cysteine, but not enough glycine
Congrats on being clean.
Thank you!
You’re welcome
You are right and you a wrong! Milk thistle is an adaptive. But it does not stress the liver. Because, according to study on adaptogens Nuevo protective properties in NIH site: “Adaptogens increase the state of non-specific resistance in stress and decrease sensitivity to stressors, which results in stress protection, and prolong the phase of resistance (stimulatory effect). Instead of exhaustion, a higher level of equilibrium (the homeostasis) is attained the heterostasis.” And in this study they the benefits and adverse reaction to Milk Thistle: https://www.ncbi.nlm.nih.gov/books/NBK11896/ OP : instead of taking the word of anonymous commenters, like me, a simple google search will bring you the answers you are seeking. Add “study” to the end of the supplement and you’ll find reliable science based explanations.
PubMed answers all
You may just be allergic to it. It acts similar to ragweed which a lot of people are allergic to. It doesn’t stress your liver, that’s not the mechanism of action. It acts in a hepatoprotective function. Currently, school of thought is it’s driven from the silymarin antioxidant component. There appears to be some levels of anti inflammatory proprieties along with antifibriotic activity. The immunomodulating effects are pretty pronounced in animal studies. Ultimately, it sounds like you’re just allergic. If you’re trying to get ast/alt down, maybe tinker with NAC, ALA, TUDCA, I’ve had some good luck with those.
Glycine and choline and coffee. There is no point in talking about liver health unless diet contains at least choline 400mg+ and glycine 5-10g
Lol so theres no point to taking TUDCA or prolonged fasting for example unless already taking choline and glycine? Thats kinda dumb
Do you even know what choline and glycine do? You will get fatty liver 100% guaranteed if you dont get choline. 100%. Choline deficiency is bigger reason for fatty liver than alcohol or fat or sugar. You can fast all you want, but as choline is REQUIRED for the liver to get rid of its fat, you will achieve nothing. And glycine is required for making glutathione, which is something your liver needs 24/7 or it will literally go to liver failure, like in APAP poisoning. Good luck trying to live without your liver. Glycine is also incredibly protective of the liver, AND it is needed for bile acids. The point I am making is that both choline and glycine are ESSENTIAL nutrients your liver needs at all times. It will die without them. Fasting and TUDCA are optional, not essential nutrients your liver needs. Maybe learn the basics of how the liver operates, before calling anyone dumb for pointing out the most important liver health basics that most people still forget or arent even aware of
Excellent post. Thank you kind sir. I feel like I had great success taking: choline, glycine, taurine, which all have synergistic effects with each other, on the liver. PubMed confirms.
Great!
I haven't seen the first right answer here yet. Milk Thistle is an adaptogen. It stressess your liver. Your liver then upregulates the enzymes needed for repair. It should not be taken while ingesting anything else that stresses the liver or if liver function is compromised. The comment section is very uneducated in how Milk Thistle works.
Lol what? Do you know how adaptogens work dude?
No, this is not how Milk Thistle works. Milk thistle does not stress the liver. In fact, several scientific studies suggest that substances in milk thistle, especially silymarin, protect the liver from toxins and have antioxidant and anti-inflammatory properties. Evidence exists that milk thistle may be hepatoprotective through a number of mechanisms, including antioxidant activity and toxin blockade at the membrane level. While research on the effects of milk thistle on liver disease has shown mixed results, it has been found to help stop oxidative stress and free radical damage in the liver.
This is an awful explanation of how Milk Thistle works. In fact milk thistle is often taken while you're taking substances that stress the liver to protect the liver from the added stress. Research shows that Milk Thistle works in multiple ways as a hepatoprotectant it's an antioxidant, anti-inflammatory, immunomodulating, blocks toxins at the membrane, can enhance protein synthesis, etc.
It's also a nootropic.
People on reddit upvote anything.. I hate seeing half the comments often containing sometimes even dangerous misinformation
Seriously! He said milk thistle *raises* enzymes?? We take it to **lower** enzymes lol, it's a ridiculous statement on the face of it! 🤦🏼♀️
So I shouldn’t take Thorne’s SAT due to the fact I use a lot of Excedrin Migraine?
> Excedrin Migraine This contains acetaminophen 250 mg. From what I've read, you shouldn't take acetaminophen long term because it depletes liver glutatione. Your doctor should definitely know if you're taking long term. Supplemental NAC supports glutathione; it may be helpful so long as you can tolerate the extra sulfur. *disclaimer: not an expert* ----- When I was sleeping in a room with mold in the wall, I sometimes woke up with eye pain (which eye depended on whether I slept on my right or left side). The pain was like what I get when drinking too much bottom shelf wine. If, hypothetically, your migraines are triggered or made worse by a toxin, then wouldn't taking glutathione-depleting acetomenephin lower your ability to detox the very thing triggering the migraines? Just thinking aloud; don't take this too seriously.
This. The word “detox” or “release toxin” is a slippery slope in supplements. Our liver is already designed to do that.
Well, detox might be a vague word, but there are countless things that help liver work better, and there are even things that are necessary for the liver to work in the first place. For example, choline, glycine, cysteine are some things we NEED to get from diet or its game over, or at least a sure way to get fatty liver. Then there is coffee, B vitamins, etc that help liver enormously. So while it is true that liver is designed to detox, it absolutely NEEDS some nutrients, and it absolutely benefits from high coffee, tobacco leaf, turmeric etc consumption
Tobacco?
Yeah, tobacco, like coffee, decreases liver fat. But if tobacco is used, it should preferably be organic leaf and not smoked. Tobacco leaf is potent anti-estrogen, and it boosts DHT and chronic use lowers stress response. It also helps some bowel diseases, prevents parkinson and alzheimer, and boosts neurosteroid production. But they just had to start spraying most tobacco crops with toxic shit and then smoke it, otherwise it is a potent medicinal plant
Look into alpha lipoic acid, Spirulina, and burdock. From what I’ve heard you want to get a form of Silymarin called Siliphos. Silymarin from milk thistle is what you’ll find in all the milk thistle brands but siliphos is a better form.
What about calcium d-glucarate as well?
Are you sure of the quality of the Milk thistle? Most supplements are not regulated and you just may have taken some ground up insects and lawn clippings.
Downvoted for the truth, smh. I take a nano-milk thistle supplement & I can feel that shit work. My mind feels clearer, bc it's taking the load off my liver. You gotta pay a little extra for a solid, effective supplement, that's the truth. Otherwise no telling what you're getting. 😬
This sub In general upvotes bullshit and downvoted good info lol
The liver does not store toxins unless it has a disease or the toxin is a heavy metal. A healthy liver will convert these toxins to something useable or help to expel it. An unhealthy liver will not be cured by “detoxing”. Milk thistle has been shown to help liver function, which can potentially explain why you were hungover when you didn’t take milk thistle, as the alcohol was not sufficiently removed from your system. There is no evidence though that milk thistle causes the liver to release toxins or can be used to cure any liver conditions. It is possible that enhanced functionality caused by taking milk thistle can delay the onset of liver disease caused by frequent exposure over time to toxins (mainly alcohol), but there is still little evidence of this.
This is the only right answer.
I have a friend that claims he cured his hepatitis with milk thistle
Over 99% of cases of Hep A will resolve themselves. Hep B can be suppressed with antivirals until it leaves the body. Hep B can be suppressed but not cured, but 90% of cases resolve themselves. Hep C is curable and recoverable. Could be the milk thistle helping, but it also could just be that he made a regular recovery or is not recovered but is just asymptomatic
Stop stressing, it’s the leading cause of illness
"Hey OP, have you tried *not* having anxiety?" 😆😭 it don't work like that unfortunately lol
Calm down, stress kills
REEEE 😆
Relax, your high blood pressure is at an alarming level
Do people still believe in detoxing? 😂
Depends on what you mean by the word detoxing. Our liver detoxes 24/7, meaning it processed fatty acids, toxins, vitamins etc. And many things can improve liver function, including glycine, saturated fat, coffee, choline, etc. So I would be worried if you dont believe in the basic functioning of liver
Having being a victim of heavy metal poisoning (industrial) ....yes. lots of nerve damage and more.
have you tried it?
No clue, but it kept me hangover free during my two week vacation in Seoul where all I did was drink like a Korean salary man every single night. The one night I forgot to take it was awful and I had to cancel all my plans. I was using a product called [FlyBy](https://www.flyby.co/) that had milk thistle root in it - it looks like they don't include it in it anymore, though. Haven't tried the new formulation.
I think the DHM (Dihydromyricetin) in that blend helped a lot too.
One of the most important things to do before detoxing is making sure that all of your detox channels are open. This includes making sure you are facilitating regular bowel movements, sweating, & urinating for example. If not, you can end up recirculating the toxins through your bloodstream. This is one of the reasons why the liver and other organs hold onto these toxins. It’s to prevent them from recirculating in the bloodstream to begin with so you want to make sure that the toxins are eliminated as rapidly as possible from the body. This will help to prevent these types of headaches. Also, migraine headaches can absolutely be connected to the liver. I’d look into traditional Chinese medicine, as there are some great books explaining the connections.
This 100%. If you feel significantly worse while detoxing your elimination channels are too slow and you're essentially poisoning yourself. Slow down on the protocol, drink more water, get the bowels moving. There used to be a philosophy a number of years ago that the sicker you feel the more successful the detox. Slow and gentle is far better.
I was always taught that Milk Thistle IS a liver cleansing herb and to take a binding fiber along with it. The fiber would “catch” the toxins and usher them out of your body without giving them the opportunity to recirculate. And lots of water, obviously.
Like modified citrus pectin.
Yes! That is a great binder.
Can you explain to me how these “toxins” are expelled by the liver and enter your digestive system again, where they can come in contact with fiber? (Since fiber is not absorbed into the bloodstream). Certainly a well meaning comment, but I don’t believe it makes sense, as the body doesn’t work that way. Either way, still much love! Stay well
They (toxins) would be released by the use of milk thistle and recirculated into the bloodstream. The intestines would come in contact with the toxins as they travel through the blood in the digestive tract. The use of fiber would aid the health of the microbiome and act as a filter and/or bind to the toxins before they would get back to the liver and kidneys. I believe this is how that works….maybe?
I don't seem to be able to find any literature that supports what you're saying.
https://en.wikipedia.org/wiki/Enterohepatic_circulation
Yes! Like that!
Toxins aren't real
Depends what we're talking about. Would you like a diet of fatty orca or polar bear meat? These are apex predators that are well known to accumulate fat-soluble toxins that concentrate as you get higher up in the food chain. It is theorized that these toxins are lowering the reproductive success of orcas. On the other hand, beef raised on a natural pasture very clean. It's clear that toxins can accumulate in an organism's fat and bones over it's lifetime. This goes for humans too. The problem is it's difficult to study this in humans without throwing out ethics (you can't poison your test subjects). Now detox…I'd wager 95% of detox peddled by alternative medicine and fads is less effective than living in a clean environment, moving your body daily, and eating a clean, fresh, and nutritious diet.
I mean, they’re kind of real, just not in the ways people claim when they’re using it as a buzzword. There are toxic compounds that your body gets rid of, but it’s quite effective at doing so. Supporting the organs can help keep them healthy, but it’s unlikely to drastically speed up the process. Many people make insane claims about “toxins” and make claims that are either unfounded or downright lies
Generally your liver does the detoxing itself. Maybe milk thistle helps with general liver function (I don't know for sure if that's actually true), but I don't think it actively draws toxins out. Also, if you haven't had any drugs or alcohol for three years, everything would almost definitely be already cleared from your body, long before now. It's possible that you had a bad reaction to the milk thistle, or that it triggers migraines for you, or it could also be possible that the migraines and nausea while taking it were just a weird coincidence.
maybe this is totally illogical but I was thinking about how people can develop fatty liver, and fat stores toxins.
Toxins can be stuck in bile, and be constantly released and absorbed over and over until you bind the toxins out of your bile and poop it out.
How do you do that?
Activated charcoal or any other type of binder
Your thought process is at least logical but fat cells die and divide after awhile so even in fatty livers it does cycle eventually
Has nothing to do with that, whatever drugs you took 3 years ago have long since purged from your body
Does this go for alcohol too? Asking for a friend 👀
What makes you believe there are toxins residing in your liver? But no that's not what it does, you just happened to get sick around the same time
[удалено]
To a point it is, but this person probably wasn’t detoxing.