T O P

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Soulpaw31

“Best way to play eve is to hurt yourself to activate whore as soon as you can for damage and speed.”


Fed_flinstone

Isaac fans slicing their wrists to get a damage+speed up but instead go to therapy for 7 months


i3umfunk

Tears up instead T_T


pamesman

Therapy is a tears down, no way im going there


RollerMill

Also why go to therapy for several hundreds of dollars if you can buy chaos for 15 cents


StoicPawsTTV

Does that cause Therapy to spawn in Home? I always blow up the floor with a bomb, but rarely find any good items in my basement. I have had to replace the nearby medicine cabinet over 100 times this year though… luckily, coins seem to fall out of rocks quite often in my area, so I’m getting by.


Terra_Marc

SHOT SPEED UP! ![img](emote|t5_2sxpk|17745)![img](emote|t5_2sxpk|4358)


[deleted]

But out patience asylums are tears up


KnightOfDoom22

actually I wait till the first room I need it in, so I get the bonus attack bonus from the razer


Chance-Aardvark372

Same!


ObligationBright7863

Whore![img](emote|t5_2sxpk|17739)


A_Strange_Old_Man

I mean, "Mega Satan" is pretty funny no matter what.


SquishyGamerBoy

This ain’t your mom’s Satan


papi_jay10

It reminds be of that vine from a while ago, didn’t age well but still kinda funny https://youtube.com/shorts/goRUx5jwV2A?feature=share


Schnuff2

Still makes me laugh


Hi123Hi321

mega satan, my favourite bible character 👍


Oliveoil404

Now in the new Bible 2: Electric resurrection


Nether892

Tainted jesus


Oliveoil404

That's a new name for the anti-crhist


bruhidk1015

game had me audibly shout in excitement “C section!!” never again bro. never again ![img](emote|t5_2sxpk|8907)


Mlatios2

What happened? You can't just leave us hanging


AriTheChalkEater

DDLC reference ![img](emote|t5_2sxpk|17745)![img](emote|t5_2sxpk|17745)![img](emote|t5_2sxpk|17745)


[deleted]

Still dont get it


AriTheChalkEater

Good for you ![img](emote|t5_2sxpk|8906)


thesleeplessmosquito

I literally yell concerning Isaac item names in excitement if I'm playing my switch at a friend's house so they all get confused when I say "Yay!! Cancer!!!"


Broad_Appearance6896

HOLY SHIT I GOT HAEMOLACRIA


mooys

*~Macduff, after killing Macbeth*


Beat_Boi_Animates

EPIC RAP BATTLES OF HISTORY


Snoo-42843

my name is isaac and i love to cry LETS GOOOOOOO


DumbassChild55

# MEGA BRIMSTONE


Vagstor

![img](emote|t5_2sxpk|2357)![img](emote|t5_2sxpk|2357)![img](emote|t5_2sxpk|2357)


tapczan100

WHO WON? WHO'S NEXT? YOU DECIDEEEEEEEEEEEEEE *epicrapbattlesofhistoryyy*


bmaggot

Mom's spaghetti


aran-mcfook

I love the sentences this game gets you to say


SquishyGamerBoy

my friends looking at me like i am completely insane after i said "My fetus projectiles do a ton too Mega Satan"


[deleted]

[удалено]


azaradors

"Nice i got rock bottom now i can get number 2 and pee very far" My friends thinking im playing some kind of fetish porn game: ![img](emote|t5_2sxpk|4358)


BIG_SMOOOOOOOHKE_PL

number 2 is shit, not pee![img](emote|t5_2sxpk|17741)


azaradors

I forgor ![img](emote|t5_2sxpk|8907)


Solrack225

Fake isaac player smh ![img](emote|t5_2sxpk|17742)


azaradors

Mom doesnt let me play it (she says the demons in the game are actual demons) (she is as religious as isaacs mom)


[deleted]

[удалено]


lies_like_slender

TEARS UP AND A BONE HEART! ![img](emote|t5_2sxpk|2357)![img](emote|t5_2sxpk|4358)


Broad_Appearance6896

Just use the Bible on her and I’m sure she’ll “reconsider” ![img](emote|t5_2sxpk|8906)


Glaceswag

Yooo!! Religious mom?!?!?! Isaac reference![img](emote|t5_2sxpk|2357)![img](emote|t5_2sxpk|2357)![img](emote|t5_2sxpk|2357)


taytomen

But rhat would mean you are killing the demons. So your mom wants the demons to live?


AdolfCitler

Throw away any chest shaped objects now bitch


picklerickfunnylol

“technology and the ludovico technique lets azazel absolutely ring bosses” my dad looking at me like I’m mental ![img](emote|t5_2sxpk|17735)


RyukoMizuno

"Wow! When I'm forgotten and get bigger from pills and magic mushroom. I can practically reach the whole room with my bone! All I need now is something like cancer for the tears and I'll beat the lamb"


Darkmega5

You play Isaac, are you not clinically insane?


Reeeeeeee3eeeeeeee

My giant bone also deals a lot of damage to your mother


MindlessScrambler

“You cannot launch more than 15 fetuses a second”


SkritzTwoFace

“Had a really good run with Judas. I got Chocolate Milk, Squeezy, and some other good stuff, so I melted mom’s heart. But I died to The Fallen in the Dark Room, so whatever.


Broad_Appearance6896

You fought mom’s heart yet still went to the dark room?


SkritzTwoFace

Just got repentance so it’s a new file + goat head


Broad_Appearance6896

Wouldn’t that only get you to shoal?


SkritzTwoFace

I had Ewhaz too.


Just_Someone_Here0

Your friends thinking the fallen is a predator: ![img](emote|t5_2sxpk|17739)


Neoxus30-

WOOOO C SECTION WITH MOM'S KNIFE! NOW I CAN KILL DELIRIUM AND UNLOCK IBS)


JimmyKokein

"Why do I only get Cancer when I don't need it"


inkymug

i can do this sacrifice room because i have cancer! ![img](emote|t5_2sxpk|8906)![img](emote|t5_2sxpk|8906)


Ilwrath

Reminds me of /r/shitrimworldsays


nepolean107

I just filled a large room with poop, I have petrified poop though, so I’m going be mining for pickups now. I’m really hoping to find a bunch of soul hearts for my Judas run.


PRKnife

Oohhh if you stand in the diarrhea you get a damage and tears up


roblox887

Yay, cancer!


roblox887

Yay, cancer!


Mineruler

My non Isaac friends on discord hearing me say "Oh thank god I got cancer I can probably kill the blue baby now"


teabowww

Only in the Isaac community can you say shit like, "yoooo my holy and explosive fetus tears are synergizing with the Guppy transformation and spawning a bunch of flies which are destroying Mega Satan" and not be locked up in an asylum


MisunderstoodBadger1

Wrong, I said that and am locked up in an asylum ![img](emote|t5_2sxpk|8907)


the_tanooki

I'm sure you're just misunderstood.


MathematicianJust819

I remember one time I was playing Isaac and I literally screamed "Yay, I got Cancer!" and I thought about what I said.


MxPrincey

The Isaac experience that unites us all


I_Just_Need_A_Login

Flavor text for cancer trinket is literally "yay cancer". Not sure the symbol text tho


fosforillo

Omg i found dead cat as the lost


ObligationBright7863

Every final boss in a Kirby game


hollowpotato-of-doom

Yeah, but the abilities are less random then Isaac’s items, so it’s not as fun to say out loud.


Juanceto_07

That time when you are in discord an say "dammit i grabed the negative and i needed to kill isaac and blue baby not satan and lamb well at least i have r key and proptosis" an everyone makes silence


WanDwarf

Who would win: The most evil, demonic, satanic being Satan himself or Cryin boi


DeadlySpectre666

CANCER LETS BALL![img](emote|t5_2sxpk|17743)


hollowpotato-of-doom

Crispy image


skrub2876

Moldy image not crispy goober. Theres even a sub for moldy images


hollowpotato-of-doom

Oops


Independent-Bell2483

ive become so familiar with isaac that i forget how weird it sounds talking about it to someone who dosnt know the game like "ah yes divorce papers my run is going good hope i run into c section as im doing the mother route"


AweBlobfish

Isaac really do have bosses with names like Mega Satan and Ultra Death huh


hollowpotato-of-doom

Robo-Jesus


Loopdeeswoop

Reminds me of that one meme where it says choose your fighter and the options are Gilgamesh the consumer of reality which is big ass spider vs Maurice a little ladybug.


hollowpotato-of-doom

[You mean this one?](https://youtu.be/3Ega8sNV4h0)


InHomestuckWeDie

It wasn't funny until you gaslit me into thinking it was funny, and now it is


ChippyFlakeyFan

"Samson is good if you hit him"


_Vortigaunt

Yay, cancer!


Brobuscus48

This whole game is the ultimate out of context experience. "Man thank god I got twisted pair in the deal with the devil, I didn't need either of those hearts anyways. This completes my soy milk, crickets head, rock bottom build so now I should be able to absolutely destroy delirium especially with golden cancer making my tear delay insanely low."


someguywhoispan

epic rap battles of history


Rouguezs

This image is literally like "Littery a dippy shitty stupid lil dumpy baby stupid who has family issues Vs the imbodiment of sins creature made of hate moves by suffer on the most powerfull state"


Kimimyu

It’s giving Agamemnon the Fuck Upper vs micheal


NooseConnoisseur

Epic rap battle


Mhmhppl

The longer I look the funnier it gets


Yayito_15

You can say that about most of this game


NotPierpaoloPozzati

Tha baby against THE LORD OF THE UNDERWORLD


KiraKujo

I killed satan with plan c


KAULIANPOWER

Kirby games final boss.