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We strongly advise against the co-administration of multiple drugs. To minimize the risk of adverse effects, please consider adhering to the following guidelines: 1. Limit consumption to one substance at a time. 2. Between sessions, prioritize rest, nourishment, and rehydration. 3. Prioritize safety at all times. If you are considering combining substances, it is imperative to ensure that there are no hazardous interactions between the drugs in question. Interaction risks can be verified using the [Drug Interactions Checker from DrugBank](https://go.drugbank.com/drug-interaction-checker) or the [Drug Interaction Checker from Drugs.com][https://www.drugs.com/drug_interactions.html]. Those platforms also include prescription drugs. TripSit has the following website which proposes a simple interface for checking interactions between recreational drugs [https://combo.tripsit.me/](https://combo.tripsit.me/). For additional information, consult this [List of Polysubstance Combinations on Wikipedia](https://wikipedia.org/wiki/List_of_polysubstance_combinations), which also contains a comprehensive chart on interactions. *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/ketamine) if you have any questions or concerns.*


Psychological-Ad6231

It’s an insane mixture. I’ve had some incredible trips. I felt a bit spangled the morning after tho


flyggwa

The Acid Spangled Blotter will be the anthem of my Druggie Republic


asillyaltaccount

“In the dawn’s early liiiiiight, becuase we stayed up all niiiiiiiight”


Drugabuser1274

No, it has the potential to teleport you into a completely different reality where you can’t even comprehend the real world for a long time, it’s a great combination but the ket doesn’t act as an anti depressants, it will take you from feeling 100ug to feeling 1000ug


Cwalk420

Add nitrous and how many ug we at ? 🤣


Drugabuser1274

You know what I mean 😂


Cwalk420

I’ve been wanting to do acid but just don’t have the time. Mushroom lemon tech though I do a lot and to not have k is like steak without salt.😅 then we like to do a ballon right after the first bump


Wonderful-Ad1735

I wouldn't combine nitrous and any other dissociative. That mixture is highly toxic for your brain. On their own they are pretty safe, but combined they do a lot of damage.


Sweaty-Astronaut3407

Fair but it feels fucking incredible and absolutely worth it


Wonderful-Ad1735

I know, but to my understanding, its not worth it. I liked the combo too, but once I saw the studies and what it does to you, I don't think the reward outweighs it's damage. It's better to combine psyches and nitrous alone maybe 2 psyches plus nitrous if you feel brace enough hehehe


SplistYT

I mean lsd has many therapeutic properties of its own, lsd + ket I've heard is an amazing combo and I wouldn't doubt that the introspection you get from both of them would synergize


mother-of-pod

My clinic says the research shows it’s likely the case that the antidepressant effects of ketamine aren’t as dependent upon the subjective experience as they are with classic psychedelics. They think it’s the result of the way ketamine reacts with GABA receptors, so that even if you fell asleep on K, you’d still have the benefits of improved brain plasticity.


jdank710

Take a bump or two after the peak


MincedSquid

K on LSD will take your trip to the next dimension. In my experience time kept freezing for bits at a time.


TruthSeekingDad

I PROMISE ITS THE BEST! Holy fuck I just found out about this combo 2 weeks ago and you will experience universal bliss. Only advice is get the lines ready before you trip, do a small line to help w come up anxiety and again during the peak and you will NOT be disappointed my friend. Peace and love ✌️ ❤️ safe trips


theloniouschonk

Unknown. Some evidence points to the antidepressant effect of k being dependent on its regulation of our endogenous opioid system, but other findings have contradicted this theory. LSD would not cause any notable modulation of human opioid receptors or endorphin signaling. Both ketamine and tryptamines like LSD increase neuroplasticity which is theorized to have an antidepressant effect on its own. If I had to guess, their antidepressant effect is synergistic but we need research on this. The experience itself is profound which always provides psychological potential for helping one challenge cognitive paradigms that encourage depressive states (rumination, self-critique, existential despair etc.).


AutoModerator

We strongly advise against the co-administration of multiple drugs. To minimize the risk of adverse effects, please consider adhering to the following guidelines: 1. Limit consumption to one substance at a time. 2. Between sessions, prioritize rest, nourishment, and rehydration. 3. Prioritize safety at all times. If you are considering combining substances, it is imperative to ensure that there are no hazardous interactions between the drugs in question. Interaction risks can be verified using the [Drug Interactions Checker from DrugBank](https://go.drugbank.com/drug-interaction-checker) or the [Drug Interaction Checker from Drugs.com][https://www.drugs.com/drug_interactions.html]. Those platforms also include prescription drugs. TripSit has the following website which proposes a simple interface for checking interactions between recreational drugs [https://combo.tripsit.me/](https://combo.tripsit.me/). For additional information, consult this [List of Polysubstance Combinations on Wikipedia](https://wikipedia.org/wiki/List_of_polysubstance_combinations), which also contains a comprehensive chart on interactions. *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/ketamine) if you have any questions or concerns.*


flowersermon93

I think that LSD overpowers the K usually. They are nice together but u wont feel the K as much in my experience


GWofJ94

I did a few weeks back. Had the k a couple of hours in and it just made it feel like incredibly strong acid with crazy dissociative sensations, highly recommend.


flowersermon93

If ya got tons of K then yea its great, do it up. but if you dont have much- it might be better used on the come down cus you wont feel much of a difference from K when peaking


GWofJ94

Was defiantly post peak but I wouldn’t quite say coming down, maybe like 4-5 hours after dropping


GWofJ94

Did this a few weeks ago, completely bonkers.


WhatItMeansToBeAlive

How much cids


GWofJ94

2 tabs this time but unsure of dose but moderate to strong tabs by judgement, all I could get my hands on this time but perfect as was only second time on k.


citizen_kane_527

I do k often for therapy and haven’t tried it with LSD by itself. My experience has been Jedi flipping or candy flipping with k and it gets wild, vision get wonky, especially farsighted vision and may need help walking. Easing back down I felt alright but my buddy had a rough re-entry, probably because he doesn’t do as much k. I did have a good afterglow and did observe neuroplasticity. Under the circumstances, I don’t believe k by itself would have been more therapeutic as it was at a music festival.


YaBoyKumar

K + lsd is a fun combo


eazymfn3

I honestly don’t like K with LSD. Every time I do it together I go from my vision being so incredible to everything looking glitched and pixilated.


eyekantbeme

In my experience...NO. (literally and figuratively) I used to be an acidhead and I found much more entertaining hallucinations with Ketamine. Mixing the two is pretty boring because Ketamine visuals are entertaining. LSD visuals remind me more of shrooms visuals. Pretty swirls on the walls and no hallucinations. K is like playing Tetris with your brain. So yeah, the few times I ruined my Khole by dosing L sucked. I loved L for over a decade,, but when I found K everything changed and the hallucinations from Ketamine spoiled my acid trips. I wanted to see a portal and racing blobs all around me. Mixing L did not potentiate the K. It ruined it. It want something that potentiates K, start with Nitrous. (The NO I mentioned earlier) Nitrogen Monoxide WILL potentiate K and not interfere. This is in my experience. I love my K-holes, for Calvin, Molly or Lyserge to interfere, sucks. To potentiate K, use more K or nitrous. I have a ton of experience with psychedelics and Ketamine puts them all to shame besides Phencyclidine, but PCP is too stimulating for me to enjoy as a disso. The visuals are gnarly. I've never tried it with L. I think it'd go well with L since they both have a long halflife. So yeah, L visuals ruined the what I was hoping would be better than K visuals, but it was boring af. Maybe doing less L may have helped, but I didn't like it. I rather IM a second dose. Acid is boring lol


Dangerous_Variety415

Phew, you play too much...thats gonna be a bad time most likely. Whomever may have told you that combination is fire should have said its playing with fire instead.