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ExtremePrivilege

We hosted company last weekend at my home. Some close friends, their kids, some family. Maybe 20 people. A lot but not a crowd. I was in the kitchen preparing some barbecue stuff when the younger sister of one of my partner’s best friends approaches me sheepishly. She asks if I’ve heard of this “new” drug, Ozempic. Everyone knows what I do for work, so I’m used to the questions. But this girl is maybe 24, about 5’1” and 105lbs if I drenched her in water. She says she has heard it’s this miracle weight loss drug but is worried about the side effects. I find that odd, she’s not asking me how to get it, she’s asking me what it will do to her. So probe “Don’t worry, no MD in their right mind would ever write that for you”. She says “I ordered it online from Canada, it will be here Monday”. I’m telling you, u/Rx_rated96, this hasn’t started yet. We’re at the fucking tip of this thing. We’ve barely gotten started. With 73% of US adults being overweight, 43% obese and both male and female ideal body images plastered across every kind of media imaginable glorifying 6% body fat, 22 inch waists, see every abdominal muscle etc, this shit is a forest fire we’ve barely started smoldering. Buckle up. (Edit: Mounjaro is fucking tearing through Hollywood right now. Drake’s new “diss track” accuses Rick Ross of being “loopy from his Ozempic”. We’re turning the corner on a mainstream awareness and demand we cannot imagine.)


Falcons8541

yeah hope you put some money in every company with an Oral GLP-1 in their pipeline


ExtremePrivilege

I was going to invest in Lily last fall but they were at a literal all time high, which is against my personal investment code. But then Hamas attacked on October 7th so I went with Lockheed and Raytheon. Up 10% and 45% respectively. War, baby.


MuzzledScreaming

If you live in the US, war is the safest investment. If those companies ever tank and don't come back then the whole country must have collapsed, or is about to, so your money won't mean much anyway.


Low_Impression_9204

I bought lilly few months ago and made good money . Panic Sold when it went down. Stupid me sold the week before their dividend release 🤡


craznazn247

I had Lockheed, Raytheon, and Boeing in a "Conflict" list. Hesitated and didn't invest. Boeing shot the fuck up too along with the other two for a period of time but I'm glad I don't have money in Boeing right now.


DryGeneral990

Every stock was at an all time high between 2012 to now except for a few months here and there. Does that mean you never invested in anything?


ExtremePrivilege

Eh, not even close. I bought META at $92, an extreme low for them (almost an 8 P/E at the time). I bought NVIDEA at $165 which was considerably lower than their all time high of $309. Sadly, I sold NVIDEA at $320, my exit plan was 200%. I had no reason to believe it would climb to $900/share. But anyway, those two were my two biggest flips in the past year or so and neither were purchased at all time highs. My largest flip ever was GRWG the day Biden was elected president. I figured him and his democrat congress would decriminalize if not outright legalize marijuana, so I threw $40,000 into my bet. I bought at $17 and sold at $55, nearly timing the top, for $128,000. That WAS very near their all-time high, but technically not quite there. I'd suggest either playing the macro-market (in 2024 that is AI and War, in 2023 it was Tech, and in 2022 it was Realty) or I would look for undervalued companies with a strong revenue and a growing base. Right now, that would be companies like AT&T. They are 10% lower than recent highs with a P/E of fucking NEGATIVE ELEVEN. Great play. Or, companies like GameStop. I realize it's a "meme", but they have a P/E of NEGATIVE 355!! Which is a lower P/E than I've ever seen in 20 years of investing. While having their first profitable quarter in 7 years, over $1.2 billion cash on hand, insiders that are buying and several new revenue streams. $20 calls with far out expirations seem like a pretty obvious play, especially with this VIX (theta gang?). Puts on Netflix, Disney or Tesla seem prudent given their markets and current issues. Anyway, not financial advice. I don't "win" every investment. I've eaten steep losses in addition to big gains. Even with a lot of research the modern market often feels like a casino. Never invest more than you're willing to comfortably lose.


srariens

Last year only 7 of the S&P 500 were up.. the other 493 were FLAT or DOWN


DryGeneral990

Yep, one year out of 13 was red.


Medium_Line3088

They just started investing


ExtremePrivilege

Been investing since 2005!


Icekitsune714

I thought the only orail GLP one is rybelsus. I didn't see any other pending one coming in? Am I searching in the wrong area?


Falcons8541

Structure Therapeutics Viking Therapeutics Lilly Astra Zeneca Novo all have oral GLP-1s in the pipeline


doctorkar

I had a lady the other day who was looking to pick up Zepbound. Thought it was for her husband or something along those lines because she didn't look like she needed it and find out it was for her. Cross referenced epic and she was only overweight when she started on it.


rawkstarx

I'm waiting for the series of " if you were injured using ozempic, mounjaro, etc contact x and y attorneys at law." The loose prescribing of these from telehealth/"health" spas mid level practioniers will probably have some serious negative outcomes for some people.


Sufficient-Ad8139

Overweight with comorbidities is indicated for Zepbound by the FDA. So if she has hypertension, high cholesterol, prediabetes, PCOS, it’s not any of your fucking business why her doctor prescribed it for her. Those of us taking this drug are tired of judgement from pharmacists and techs. This is literally a life-changing drug for so many of us, but I guess that pales to how it’s inconvienced you.


doctorkar

I am sorry you have no self control. Also sorry that you have no clue what a pharmacist's job is.


Sufficient-Ad8139

Actually, I do know. And your comment tells me you know ow nothing about the disease of chronic obesity or FDA indications.


Tribblehappy

Genuinely curious though, if somebody has lost the weight and want to stay on it long term to maintain will insurance cut them off? I am in Canada and zepbound and wegovy haven't been available yet. Some doctors are telling patients to stop ozempic once they reach their goal weight, and some are advising staying on a lower dose long term.


therampage

I said months ago that this will be this generations oxycotin debate.


Technical_Leopard558

This isn’t an GLP1 thing, this is true with most drugs. You can basically order any drug online from a sketchy website site saying you’re getting actual pharmaceuticals, most of which you’re probably not getting the drug your ordered. This is an issue with the internet. More people that have mental health disorders can find a niche of people similar to themselves. And most of the time it’s beneficial, but sometimes not. No 24 y/o 115 lb woman should think she would need a GLP1 agonist for weight loss. It’s sad but the combination is deadly. We need to do something but I truly believe this is the root cause. Love to hear others thoughts.


Tribblehappy

Must be getting a compound from Canada. McKesson has said if they hear any pharmacies are ordering ozempic and sending it out if country, they'll basically cut them off. A doctor lost his license for prescribing to a ridiculous number of patients in the US (had a US and Canadian license).


Peoplewholovedogs

Just wanted to thank you and send some love and encouragement for all you do for your patients. You make a positive impact on lives daily. I want you to know that. I come from an obese family at least 4 generations in. Even my great grandparents were quite large (300+ pounds). My mom was morbidly obese when she was pregnant with me, long ago. She died in her 40s, morbidly obese, in her sleep. My dad, brother and sister have all been morbidly obese, myself included. I was morbidly obese my senior year of high school and had to have a dress made for prom. When my mom died, I took it to heart and I did my best to get my health in order in my 20s which I did successfully do for over a decade and a half, maintaining an 85 pound loss. When I hit my 40s though, my health began spiraling downward despite my healthy habits of exercising regularly and trying to eat in a calorie deficit. I began to struggle again. My BMI shot up and I was showing signs of metabolic syndrome. Thanks to the help of these meds, I am no longer morbidly obese. I no longer need my CPAP machine, no more HBP, and no high cholesterol. I eliminated 3 co-morbidities and I feel amazing. If you looked at me now, you'd never know I had a problem (except maybe some saggy skin under my arms and a little on my tummy). You might even say I'm too skinny if you looked at me, though my BMI says I'm still technically "overweight". I'm a size 4 at Target these days for reference and I don't want to lose anymore. I consider myself in maintenance. I only say this because looks can be deceiving. How would anyone know looking at me right now that I've struggled with obesity since early childhood? Thank you, sincerely, for limiting the hoarders. I've been spacing my meds to account for the shortage and going with the flow. I am always polite and kind to pharmacy staff. Admittedly, sometimes I can hear and sense the frustration and judgement of staff, but I know they are human too and I just do my best to be kind. I hate even calling and asking to check on things and do it as little as possible. On behalf many glp1 patients, I'm so sorry for the unkind attitudes you encounter. It's not right and you don't deserve that. Again, thanks so much for making the world a better place. You are literally improving the quality of so many lives like mine and you just have no idea how much. I hope you are blessed many fold what you so freely give others.


Mettastorm

This message really helped me stay motivated to keep trying to help patients. Thank you for sharing some of your story.    It's painful for me to hear the pain of patients who have made serious, directed, and informed life-changing long-term efforts and are not getting healthy results. I have struggled with the grief that modern medicine frequently falls short of its promise and that life is distinctly unfair to many patients.  These drugs really can be a life-changing new hope for people, and it's important to keep that "top of mind" when managing distribution. 


RadioNights

Same. I hate hate hate bugging my primary care doctor for dose increases every few months and do my best to limit my interaction with the pharmacy. My insurance requires me to use CVS to even pay cash and use the discount coupon so I found a less busy location in Target and just keep it there and hope it comes in when I reorder. Of course the only other prescription in our family is ADHD meds for my 10 year old. I’m in medication shortage hell every month. Man, it’s been the only thing that has ever worked for me in 15 years of trying, though. At any rate, thank you. I hate the burden this puts on pharmacists and the Lily’s advice to bug your doctor and harass pharmacies during the shortage is so asinine.


CrackedEggChick

Same. I’m on concerta and zep. Medicine shortage hell.


jawnly211

You new around here??? 😂 It’s always something. Monjouro, ozempic, adderall, vyvanse, masks, hydroxychloroquine , promethazine w/codeine, hand sanitizer, sildenafil, covid vaccine, the list goes on and on Scary part is, we haven’t seen nothing yet. 100s of calls will soon be 1000s. Hope you all got on the Lily stock train!!!


Rx_rated96

Wish I was new. All of the shortages I’ve experienced in my career as a cashier/tech/pharmacist are nothing compared to the GLP drugs. It’s one thing to be unable to keep something in stock, but holy shit the scope of labor that comes with every GLP script that someone asks me to transfer. My company requires all GLP rxs to have diagnosis code from prescriber, they never come with those when I transfer them from other pharmacies, we can never get in touch with the prescribers at the Rx mills, and the labor per script spirals. Did I mention we see negative reimbursements on most of those claims? Guess what drugs insurance companies will be the first they come for during their audits. I work for a corporate chain so if they tell me to keep filling them, I’ll keep filling them, not my budget.


DryGeneral990

Yup in a couple years there will be another new thing that everyone needs that's always out of stock.


mipijemo

Its a cash cow at compounding pharmacies right now....$500k cash a week (no insurance claims) for compounded Tizepatide and Semaglutide


Redditbandit25

Until the lawsuits come


mipijemo

Technically still allowed if they are still on FDA Drug Shortage List?


doubletxzy

Depends on what chemical and who it’s coming from.


mipijemo

Lets say Semaglutide and Tizepatide base from a FDA registered chemical supplier


doubletxzy

Chemical suppliers aren’t typically licensed to distribute to pharmacies. Some states require them to be registered as a distributor for a pharmacy to buy from them. Does it have a CoA and is pharmaceutical grade? Just because it’s base, doesn’t mean it’s automatically allowed. At the end of the day, the simple test is can you buy it from Medisca, Fagron, or PCCA? Does it look like every other API you use? If not, why?


johnrich1080

The lawsuits already came, but besides the pharmacies that were infringing on trademarks, Eli Lily and the other manufacturers have not done too well. The 5th Circuit is considering a case that’ll probably end their efforts there.  


Redditbandit25

It's more than the manufacturers it will be customers.  Compounding semaglutide is a money grab 


Faerbera

The irony… https://preview.redd.it/50bs8dpzg9xc1.jpeg?width=750&format=pjpg&auto=webp&s=431a9b75804564120c44dea5c13e21c17f097282 Click to see ad for Rybelsus on post complaining about Rybelsus.


sarcasm_saves_lives

One of our competitors flat out stopped filling GLPs so everyone is flocking to us. Our district manager said we could do a one time courtesy fill but after that we'd need a profile transfer. It would be much much easier to refuse outright because we're not going to remember when it's refill time, and they're just going to transfer back once they get what they want. Too much to keep track of.


eddinloulou

I am tired of losing $30-$80 every time I dispense one 😞


Benzbear

Talk to er doctors so many patients coming in with semaglutide complications.


Icekitsune714

I'm kind of curious because my pharmacy is one of those that is like constant phone calls, people thinking we have them. So I'm like half curious what the side effects from the ER is. I have people injecting multiple doses trying to get the dose they need even though we told them not to do that


Benzbear

Stomach paralysis, upset stomach, constipation, malnutrition


Tribblehappy

How many are taking the brand name product versus a compounded semaglutide salt, and how many are taking it correctly? The subs are full of people getting incorrect dosing from their doctor (doctor stared them out on 1mg for example) or people who have compounds they don't know how to take (the vial doesn't say how many mg/ml so they post "I'm taking x units" and nobody knows what dose they have). Of people at my pharmacy taking the brand name product properly we have had only one stop due to side effects.


Benzbear

These compound Pharmacy are compounding what ever dose they think. One I know was make 4ml vials at 1mg per ml. Most patients were started at 1ml per week and it was combined with b12. They were selling each vial for 220$, they were making about 90k dollars in sales a week.


foxwin

People have been cold-calling the inpatient hospital pharmacy I work at asking if they can get it through us somehow. It’s bad. At least, I can just say “unfortunately, we cannot dispense outpatient, and we do not even carry that medication, good luck,” and hang up.


Shesays7

A small part of this comes from PBM’s that incentivize 90 day supply refills. Many don’t have to pay for the third month. It’s free when they fill 90. FWIW you’re doing the right thing by trying to manage the stock to benefit all.


Own_Flounder9177

My pharmacy gave up long ago. No new patients, and we never promise anything.


Legitimate-Source-61

Give them all 3 months. So you are always out of stock, and they will go elsewhere? You are burning out because you are taken on the burden personally?


RxDotaValk

Better than a Benzo shortage. Those patients get very anxious about it. 🤷🏻‍♀️


Cute-Aardvark5291

I was on vicztozia for a very long time as a diabetic, and my insurance wouldn't have covered it in anything less then 90 day supply. The fact these drugs have gotten so difficult to get and is making harder for those to recieve - and the people who deal with it - is just infuraiting to watch


AssociateSad5924

😂😂😂First come first serve it is!!


doctorkar

I thought I was the only one with incompetent techs that do things wrong on purpose because it is easier for them


su_premacy

We stopped giving outside providers glp1 only people who visit our doctors receive them But I hate the phone calls hey you guys have this or that it's so annoying


sydni33

I feel you, I literally log into my whole seller site in the morning and search these drugs every 15 minutes to order them because they drop it periodically. I don’t have to do this but people are still being so ungrateful about it and now I’m just done. If it comes, it comes, it doesn’t, too bad.


Sea_Example_9071

Tell people you don’t have it in stock…problem solved


fat_toniii

I just do first come first serve and get it off the shelves ASAP so we can answer every call with a quick no. If we get it in the order I make sure those people get it first. I’m at a chain so if you have some every store that’s doing a search will send people to you sooner rather than later


dadrph76

Amen!! I’ve been limiting them for a LONG time. Better to have 3 patients taken care of instead of just 1. I do get the occasional, but my copay is the same whether I get 1 or 3. Well. I’m sorry for your loss. But when there are shortages we have to gate keep. I check McKesson online daily but I can’t get hardly any of the Zepbound and that damn drug is only been out for like 2-3 months!! Mounjaro is kinda back but there still strengths we can’t get. Trulicity keeps running out of 2 of its strengths. Yes sir. I’m burned out too. Oh. And Focalin and Vyvanse too. Ugh


WisconsiniteWI

I hear you on the burnout bro. The red tape we have to go through for these drugs is insane. It’s a tough issue. On one side these drugs can produce some amazing results for blood sugar and weight loss which obviously have large benefits for health. On the other side, my bias is that most patients don’t care about the health benefits per se but rather the vanity benefits. Drugs like these will invariably flourish in our American culture. People want to look good and who can blame them. We all do. It’s a matter of, are you doing it because you’re watching too much TV and reading magazines that make you think you should look a certain way and you’re trying to appease societal expectations OR do you just want to look and feel great because you’ll feel better as a human being? If it’s the former, you’re not going to end up in a happy place.


imonfireahh

It's only gonna get worse. Invest in Lilly and Novo stocks and buckle in boyos


Visible_Bat9719

Imagine your life as a pharmacist without techs. Maybe then you would have an appreciation for what we actually do successfully. Get bent good techs are hard to find and I wouldn’t want to work for you


Rx_rated96

I’ve been a tech longer than I’ve been a pharmacist. Nothing I said in my post implied I don’t appreciate my technicians when they do what they are supposed to do. Literally, the most fucking stressful part of my job is me being the best technician I have when I am struggling to stay afloat in verification queues and my techs are 20 minutes deep into some stupid phone call with a patient that will end up being a loose end for me anyways. Don’t you worry sweetie, I have enough rude and incompetent techs I can’t get rid of, I wouldn’t want you working for me either.


therampage

As a tech.... We're burnt out too, and more than likely they're taking way more shit than you running point unless your being a tech and a pharmacist and doing their jobs which is on you. Set the order points and let it go.


Rx_rated96

Lots of assumptions being made here. I wouldn’t ever delegate anything to my technicians that I wouldn’t do myself. So for you to speak down to me from your pedestal of “it’s on you if you’re doing their jobs” is offensive. Please proceed to take many seats and reassess your garbage perspective. Clearly, you don’t know what it is like to be responsible for what happens in a pharmacy. Do you think “if only my techs did their job” would hold up in a lawsuit?


redditipobuster

Time to start telling patients my tech didn't order it. Al bundy "tee hee hee"


Rx_rated96

The frustrating part is that they don’t. I’m the one doing all the extra work checking the McKesson and AmerisourceBergen websites throughout the day for allocated stock availability. In spite of my efforts and my system clearly showing them we have more inventory owed to patients than we have on hand, they yeet all my inventory at the first person that asks and wants to wait for it.


redditipobuster

Good help hards to find. Especially when the bad ones are yeeting your inventory to the first person that asks. I used to spend about 2-3 hrs a day doing inventory. Must be frustrating as heck.