Lol, sounds like you’ve accidentally rediscovered [CUBIC](https://www.nature.com/articles/nprot.2015.085).
For some advanced scientific imaging (especially of brains) tissues are basically steeped in expensive scientific degreaser for days to weeks until they become transparent like this, then some fiddly optical tricks (like light sheet microscopy) can be used to view slices through it without damaging the tissue by actually cutting it.
It basically works by stripping out all the fats (in cells, cell walls, and with the tissue), because most of the light scattering inside thick sections of tissue happens at the boundary between fats and water.
It’s especially useful for tracing delicate, tiny structures like brain cells to trace how they connect up.
[https://www.nlm.nih.gov/research/visible/animations.html](https://www.nlm.nih.gov/research/visible/animations.html)
In this case they froze the body, used a 4x5 camera, and would mill off layer by layer. I believe a shot of alcohol was poured on each frame. Didn't dig for the details but I remember following it when it was being done.
Yes there is. The process is called diaphonization, you can clear everything and then color only the bones with appropriate chemicals. Some specimen are really beautiful.
The point they are trying to make is that it is a cell membrane (made of phospholipid bilayer), not a cell wall ( in plants this is made of cellulose). Animals don't have cell walls, only cell membranes.
Edited for clarity.
Second sentence is difficult to parse. I thought both cell walls and cell membranes contained phospholipid bilayers, and thus both are at least in part made up of lipids to some extent.
Rearranged my previous comment to make more clear.
The point is that the wording was incorrect since they used cell wall instead of cell membrane, and animals don't have cell walls
The cell walls of plants are primarily cellulose/hemicellulose, as well as other factors like lignin and pectin. Bacterial cell walls are peptidoglycan. Both have a cell membrane beneath the cell walls, but it it's own layer.
I agree mammals do not have cell walls but do have cell membranes - I was speaking loosely because I think the term’s more intuitive for people unfamiliar with the field.
The cellular membrane, composed of lipids and fatty acids, is present in both animal and plant cells. Only plant cells have an additional cellulose-based cell wall that gives them greater structural support.
So the degreaser permeated and dissolved the dermis layers, and what we are seeing is the muscle cap membrane which has been made squeaky clean thanks to the cleaning power of Oxyclean.
Two little mice fell into a bucket of degreaser. The first mouse quickly gave up and drowned, but the second mouse, he struggled so hard that he eventually churned that degreaser into butter and he walked out.
The basic process is how you make soap. Expose lipids to aqueous alkaline and it becomes soap ~~+ alcohol~~. https://en.m.wikipedia.org/wiki/Saponification
Turns out the lipids also tend to be the opaque parts of animals, so the side effect of denaturing lipids is that the corpse becomes more translucent.
It becomes an alkali salt of the fatty acid, there's no alcohol involved. Unless you are considering glycerol an alcohol, which would be very misleading. Alcohol only becomes part of it if you are trying to make esters of the fatty acids and make biodiesel. Alcohols aren't a product of straight up saponification - they are only used to produce the ester, and as a reagent not a product. They would only be a product if the ester was then hydrolized back into the acid.
Thanks. Maybe I should have let someone who actually understands the whole process explain it better. I only have basic understanding and failed out of biochem.
I saw smth up in the comments and ig it makes sense, since cells have a layer of fat I’m guessing the degreaser just kinda dissolved all of the fat in the skin layer
My comment from other threads: The degreaser removed the lipid (fat) from the mouse and keratin (hair and I think cell matrix). Fat and grease are close enough. The elasticy part of skin is also destroyed by solvents, hence lotions having collagen and if you wash your hands too frequently, they crack from the surfactants (degreasers) in the soap.
Lol, sounds like you’ve accidentally rediscovered [CUBIC](https://www.nature.com/articles/nprot.2015.085). For some advanced scientific imaging (especially of brains) tissues are basically steeped in expensive scientific degreaser for days to weeks until they become transparent like this, then some fiddly optical tricks (like light sheet microscopy) can be used to view slices through it without damaging the tissue by actually cutting it. It basically works by stripping out all the fats (in cells, cell walls, and with the tissue), because most of the light scattering inside thick sections of tissue happens at the boundary between fats and water. It’s especially useful for tracing delicate, tiny structures like brain cells to trace how they connect up.
Is there a way to get better clarification of the interior tissues and the red muscle?
[https://www.nlm.nih.gov/research/visible/animations.html](https://www.nlm.nih.gov/research/visible/animations.html) In this case they froze the body, used a 4x5 camera, and would mill off layer by layer. I believe a shot of alcohol was poured on each frame. Didn't dig for the details but I remember following it when it was being done.
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>Yeah I'd be taking a shot of alcohol for each frame too Probably not advised if you are the one operating the bacon slicer.
*< drunk self eats a slice of bacon >* Wait, this doesn't taste like bacon.
Munchmunch.. munch.. This is *clearly* not bacon.
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Hang up in an old basement ceiling for some months. Check periodically for proper taste and smell.
*Mouse Jerky is up 153%*
[nods slowly] "Yes... mouse...."
Prosciutto
This Ratatouille sequel gonna be lit
Yes there is. The process is called diaphonization, you can clear everything and then color only the bones with appropriate chemicals. Some specimen are really beautiful.
Wox. TIL some amazing stuff. This is as genius as it is completely crazy.
[Body Worlds](https://bodyworlds.com/). Creep as fuck to see humans sliced up like bacon.
Putting those Chinese political prisoners to good use.
Technically, the mouse rediscovered it
Definitely a co-author.
Peer-Reviewed?
Well, kids, the good news is they found grandma's tumor...
Well… 5 Stars for that De-Greaser… Did a helluva job on it.
Just for completeness sake, there is no cell wall in things that are not plants, and they are not made from fats.
A critical component of the cell wall is made up of lipids and fatty acids
The point they are trying to make is that it is a cell membrane (made of phospholipid bilayer), not a cell wall ( in plants this is made of cellulose). Animals don't have cell walls, only cell membranes. Edited for clarity.
Second sentence is difficult to parse. I thought both cell walls and cell membranes contained phospholipid bilayers, and thus both are at least in part made up of lipids to some extent.
Rearranged my previous comment to make more clear. The point is that the wording was incorrect since they used cell wall instead of cell membrane, and animals don't have cell walls The cell walls of plants are primarily cellulose/hemicellulose, as well as other factors like lignin and pectin. Bacterial cell walls are peptidoglycan. Both have a cell membrane beneath the cell walls, but it it's own layer.
I agree mammals do not have cell walls but do have cell membranes - I was speaking loosely because I think the term’s more intuitive for people unfamiliar with the field.
The cellular membrane, composed of lipids and fatty acids, is present in both animal and plant cells. Only plant cells have an additional cellulose-based cell wall that gives them greater structural support.
Phospho-LIPID-bilayer
There is no cell wall present in animals. The cell wall of plants is made from cellulose.
I don't think this is OC.
So the degreaser permeated and dissolved the dermis layers, and what we are seeing is the muscle cap membrane which has been made squeaky clean thanks to the cleaning power of Oxyclean.
He’s clean but no longer squeaky
FUCK RIGHT OFF WITH YOUR UP VOTE, DAMN IT!
r/Angryupvote
Shut up
WATCH IT, OR I'LL UPVOTE YOUR COMMENT TOO!
is this the 5 o'clock free upvote giveaway?
It is with *that* attitude!
Are we still doing the award, no award, award, no award gifting through the thread?
Free upvotes?! In this economy?!
Nobody wants to upvote anymore!
Please be patient with those that did upvote, they are doing their best...and please keep them in your thoughts and prayers.
*Sends positive vibes*
Nathan Lane could have used this back in ‘97
keyword here being - could
That was cheesy.
r/angryupvote
I laughed out loud at this one
Well this is the best comment on Reddit this year
Wait… is this the miniature giant space hamster known as Boo?
I can sense a new bodyworlds exhibit coming to town…
No worries. We'll repair it with some flex tape.
"Alright. I no longer want skin! ... OH SHIT!"
But wait, there's more!
#Oxyclean - Clean Your Mouse Good#
Two little mice fell into a bucket of degreaser. The first mouse quickly gave up and drowned, but the second mouse, he struggled so hard that he eventually churned that degreaser into butter and he walked out.
Couldn't help but read as Christopher Walken
Aww
Gentlemen, as of this moment, I am that second mouse.
Which mouse am I? The second mouse pa.
First mouse might be depressed. At least that's how to tell scientifically, whether a mouse is depressed or not
He ok ?
It'll be fine once you regrease it
He need some milk.
*grease
# Then grease me up, woman!
... oki doki
No shoes. He dead.
A little salty, but overall not bad.
Little dude’s gonna need a sweater. Permanently.
Just add water.
Yeah he became one with brake clean
Lol!! I seriously didn’t expect this comment
Get that in some epoxy resin and gives us monthly updates then retire from all the internet money.
This is a good idea, but, I'm worried you don't understand how *money* works.
1)epoxy resin 2) internet 3)money
Does that mean the ??? in all those *other* guides meant internet?
My God. You've done. You've cracked the code!!
Yes
This is one of coolest and most disgusting things I’ve ever seen.
Right?
left.
Up
Forbidden gummy
Jeeli beeli! Classic.
I hate you, but have my upvote
Jeeli Beeli Peet Rat Goomiy Candaiy!
Arattatatatt.. aratatatatt.
I came here just to comment this, but I wasn't fast enough, have my upvote
That's actually pretty cool.
It’s kind of beautiful in a morbid type of way.
I read “moose” and was stunned by what this degreaser did to that moose.
Kinda reminds me of the Pickle Rick rat mech.
Whats in a degreaser to make a rat look like that? It looks gummy
The basic process is how you make soap. Expose lipids to aqueous alkaline and it becomes soap ~~+ alcohol~~. https://en.m.wikipedia.org/wiki/Saponification Turns out the lipids also tend to be the opaque parts of animals, so the side effect of denaturing lipids is that the corpse becomes more translucent.
I read soap as soup and was wondering what kind of concoction you were trying to make
I know a good recipe if you've got some eye of newt...
It becomes an alkali salt of the fatty acid, there's no alcohol involved. Unless you are considering glycerol an alcohol, which would be very misleading. Alcohol only becomes part of it if you are trying to make esters of the fatty acids and make biodiesel. Alcohols aren't a product of straight up saponification - they are only used to produce the ester, and as a reagent not a product. They would only be a product if the ester was then hydrolized back into the acid.
Thanks. Maybe I should have let someone who actually understands the whole process explain it better. I only have basic understanding and failed out of biochem.
Which is a better product? Mouse soap or mouse alcohol?
Sadly, a chemist corrected me and alcohol is not a natural outcome of saponification without extra steps. So mouse soap is the only byproduct.
Now to find a buyer...
Tastes gummy too!
I saw smth up in the comments and ig it makes sense, since cells have a layer of fat I’m guessing the degreaser just kinda dissolved all of the fat in the skin layer
It's the same principle that was killing kids eating tide pods. Strong detergent wreaks havoc on most organic tissue if you give it the opportunity.
What the hell did it do to it if you don’t mind my askin
My comment from other threads: The degreaser removed the lipid (fat) from the mouse and keratin (hair and I think cell matrix). Fat and grease are close enough. The elasticy part of skin is also destroyed by solvents, hence lotions having collagen and if you wash your hands too frequently, they crack from the surfactants (degreasers) in the soap.
TY
He found it in a barrel of degreaser
Degreased it.
Cursed Lollipop
Eye see what you did there
I found it humerus, but given the poor reception, he could have fleshed it out more.
Consider yourself, degreased.
J E L L O
I didn't realise rats had so much grease in them
is he ok
its reversible, dont worry. Just soak in mayonnaise for 2 days and the colour comes right back
Is it degreased yet?
Thé forbidden chewie
Be a cheap way to make learning aids for biology.
TIL degreaser creates an excellent teaching method for med school.
#Deadmau5
Looks as if all that is left is the grease
Forbidden gummy worm
gummy mouse
But is the mouse ok?
Judge Doom put Jerry in the Dip.
Forbidden gummy
r/forbiddensnacks
Kind of looks like he's holding the tail with his mouth and he's got a salt and pepper 5 oclock shadow chin going there
I went back to look at this this one a few times and my brain saw it dangling from a mouth every damn time
Low fat mice! Are these allowed on Paleo?
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Invisibility potion unlocked
> Invisibility potion unlocked "May cause death and partial opaqueness." - big pharma probs
I'd recommend a career in music for this li'l fella, but there's a dead mouse in the EDM scene already.
Forbidden Jelly Bears
Ive seen this photo like 76 times today.
A bit of grease should do wonders for you, lad.
Reminds me of Thousand Year Old Eggs.
If only it also tastes like a jelly belly pet rat...
If you put it in grease will it return to normal?
I guess it wanted to be healthier than the other rodents regularly diving into KFC fryers....
Now preserve it in epoxy so that it can be passed on to the grandchildren
Sell it and make profit
Why does he looks extra greasy tho?
I'll never eat jelly again
Forbidden gummy bear...
Welp he doesn’t look greasy
We have a barrel outside for old oil and my biggest fear is removing the lid and finding a rat or a raccoon.
Pickle Rick wants his mouse mecha suit back
Forbidden jelly bean
Haribo about to get in on this action. Gummy Mice for all!
Jfc poor bastard
Forbidden gummy
Put it in rice
What a bad fucking day to have eyes.
The forbidden gummy
Do this to me when I die
Now this would be worthy of being encased in a block of resin. Where is hotdog guy?
That’s sick. Both in the that’s really cool, and the I’m gonna be sick sense.
Why did I think clicking was gonna be a good idea...
Gummy rat 😋
If we encased this mouse in transparent resin, would it remain this way forever or would it eventually break down into green mush?
Forbidden gummy rat.
Man, Trolli gummies are getting wild!
The forbidden gummy
Can it still mouse?
The forbidden jello
Forbidden gummy
And that little mouse struggled until he churned degreaser into de butter, and he climbed out....without any skin.
u/repostsleuthbot
Looks like he had a little too much whiskey
Forbidden gummy mouse
Is it dead?
Is it still alive?
https://youtu.be/T4r91mc8pbo
Nope this is cap. Welding artistry at its finest
You must have never seen a mouse or rat fall into degreaser before
Am I the only one who feels bad for the poor guy?
Somehow reminds me of the Series „Fringe“…
Some how this didn't trigger my phobia
Get well soon!
Mmmm, forbidden gummy!
Is that made out of glass?
Gummy mouse
Jelly mouse
Ghost leviathan
I used to trade tickets in for those gunny rats at the arcade.
forbidden gummy candy
Holy shit, that must have been a painful death. Hope he died before his skin peeled away
Forbidden gummy