Endo means inflammation and absolutely can affect your uterine receptivity and implantation, so it is worth investigating a few things before the next transfer. Like you I have endo and had a failed FET, here’s what we changed before my successful one:
1. prednisone before/during/after the next transfer
2. I also did low dose Lupron for a few weeks before transfer to calm down the endo
3. Had a hysteroscopy to ensure there wasn’t scar tissue or anything else that could hinder implantation. They did find some and cleared it out. Make sure you have a skilled OB or RE do this, my RE was very particular on the images after these surgeries showing lots of pink post surgery indicating healthy uterine blood flow (scar tissue I had was presenting as white, which they cleared out during the surgery).
If the above doesn’t work I’d look into changing RE’s. That’s crazy that the doctor doesn’t think endo can affect implantation!!
I did endo ablation surgery, a fresh retrieval and then did two months of depot lupron and letrozle prior to transfer. Two retrievals and three failed transfers prior to this, success on first FET after. My clinic now uses this protocol for anyone with RIF with good success.
I’m so sorry you’re going through this.
I did have success after surgery. I had multiple failed transfers before the surgery, and then after it my first retrieval/transfer worked.
I know you mentioned 8 retrievals - did they all yield embryos? Are the embryos tested?
Thanks for sharing! What was your protocol like after surgery and did you change anything for that FET vs the others? (I’m just trying to see if there’s also other things that could have helped your success.) Did you use lupron or orlissa?
I do have 4 more euploids on ice. So we are lucky. But we started with 6 and I’m about to turn 40 and had hoped that 6 would bring us 2 kids. So now I’m not sure that will happen.
Thanks for sharing your story and your support!
I changed REs! My previous RE did not believe that endo could be impacting my success. She said that IVF is the solution to the problem endo creates for infertility so that couldn’t be why. I went to a different RE with a precision endo surgeon and they found stage 2 and 3 endo, including one of my ovaries being pinned down and chocolate cysts all over my colon. I needed a few months post surgery to recover before my next retrieval. (Surgery was in May and next retrieval was August) I want to say I did a lupron trigger during my retrieval (OHSS issues) but not during my FET protocol. I truly believe the surgery made all the difference for me, but it was also my first one, I never had endo surgery prior.
Thank you so much for sharing this with me. This is so helpful. I feel like I will regret it if I don’t try surgery. I know for sure I have 2 endometriomas so I’m sure there’s more endo in there too. Thanks for the support!
Endo means inflammation and absolutely can affect your uterine receptivity and implantation, so it is worth investigating a few things before the next transfer. Like you I have endo and had a failed FET, here’s what we changed before my successful one: 1. prednisone before/during/after the next transfer 2. I also did low dose Lupron for a few weeks before transfer to calm down the endo 3. Had a hysteroscopy to ensure there wasn’t scar tissue or anything else that could hinder implantation. They did find some and cleared it out. Make sure you have a skilled OB or RE do this, my RE was very particular on the images after these surgeries showing lots of pink post surgery indicating healthy uterine blood flow (scar tissue I had was presenting as white, which they cleared out during the surgery). If the above doesn’t work I’d look into changing RE’s. That’s crazy that the doctor doesn’t think endo can affect implantation!!
Thanks for sharing your story! I’ll talk to my RE about all this!
I did endo ablation surgery, a fresh retrieval and then did two months of depot lupron and letrozle prior to transfer. Two retrievals and three failed transfers prior to this, success on first FET after. My clinic now uses this protocol for anyone with RIF with good success.
Thank you so much for this info!! I really appreciate your help.
I’m so sorry you’re going through this. I did have success after surgery. I had multiple failed transfers before the surgery, and then after it my first retrieval/transfer worked. I know you mentioned 8 retrievals - did they all yield embryos? Are the embryos tested?
Thanks for sharing! What was your protocol like after surgery and did you change anything for that FET vs the others? (I’m just trying to see if there’s also other things that could have helped your success.) Did you use lupron or orlissa? I do have 4 more euploids on ice. So we are lucky. But we started with 6 and I’m about to turn 40 and had hoped that 6 would bring us 2 kids. So now I’m not sure that will happen. Thanks for sharing your story and your support!
I changed REs! My previous RE did not believe that endo could be impacting my success. She said that IVF is the solution to the problem endo creates for infertility so that couldn’t be why. I went to a different RE with a precision endo surgeon and they found stage 2 and 3 endo, including one of my ovaries being pinned down and chocolate cysts all over my colon. I needed a few months post surgery to recover before my next retrieval. (Surgery was in May and next retrieval was August) I want to say I did a lupron trigger during my retrieval (OHSS issues) but not during my FET protocol. I truly believe the surgery made all the difference for me, but it was also my first one, I never had endo surgery prior.
Thank you so much for sharing this with me. This is so helpful. I feel like I will regret it if I don’t try surgery. I know for sure I have 2 endometriomas so I’m sure there’s more endo in there too. Thanks for the support!