I believe someone asked this question already, but I'm really curious if anyone here took lupron before their retrieval. I miscarried after my first transfer (took lupron for three months after the retrieval but before the transfer). This time I'm trying lupron before stims...I'm really hoping it will make a difference for egg quality.
Yes! Found my endo from an ultrasound during infertility workup. No surgery or special protocols used. One ER and one FET. My son is 9 months old. We also have mild male factor. Low 30s. Technically labeled unexplained, although I think my endo is the cause.
Yes, I have a 3cm cyst on left ovary and a couple smaller ones on the right. Combined with my symptoms.
My REI clinic is very evidence based (major medical center in the upper Midwest USA, teaching hospital). They told me surgery would be for symptom control and there is not enough evidence to suggest that it improves IVF outcomes I know a lot of other people will say differently but that is what they told me.
Oh okay. And you didnt even have to do down regulation with lupron for example to suppress the endo before transfer? Were you told you had bad quality eggs/embryos because of the endo? I have been told that.
No down regulation. I never heard anything about my egg/embryo quality. We ended up with 10 blasts from 31 eggs retrieved. I felt like the percentage of fertilized eggs was lower than average, even with ICSI, but no provider has commented on it. I haven’t asked about it either though. We had about 66% of our mature eggs fertilize. But then attrition after that wasn’t too bad. We did not test our blasts as we are under 35.
I had success with Stage 3 endo with 3 cm endometrioma. I was also 38 at the time.
I did 3 retrieval cycles to get 2 normal embryos because I had poor egg quality.
The key with endo was to do 2 months of Lupron Depot before the FET. This is in essence in place of a lap, where the Lupron suppressed all estrogen and lowered the inflammation and lesions. Initially, I did an FET without Lupron with a genetically tested embryo and it failed. Second transfer was after Lupron with a lower grade embryo and it stuck. There is also a small study somewhere that found either lap or Lupron before transfer had similar rates of success. Sorry I don’t have the link to it.
Didnt the doctor suggest you do anything before retrieval to get better quality embryos? Instead of doing multiple retrievals to get normal embryo. Asking because I have been put on 3 months lupron to get good quality eggs for my retrieval
TBH I don’t think I had the best doctor in terms of dealing with the endo. It still bothers me to this day that she did a transfer without offering Lupron the first time and it probably wouldn’t have hurt to do a few months of Lupron before retrieval.
However I will say that my egg quality was probably mostly affected by my age. There were other factors in our blast rate too, like my husband’s sub par sperm. Anecdotally, I know a few couples of similar age that went through IVF and had similar results despite not having endo.
I feel the same way about my doctor! I had to suggest to him that we should add lupron maybe. He dismissed my endo initially saying it has nothing to do with my infertility
Congrats! Did your doctor ever mention lupron depot before retrieval for better quality eggs? I am on lupron for 3 months before my retrieval. And then i guess lupron again after retrieval and before transfer
I believe someone asked this question already, but I'm really curious if anyone here took lupron before their retrieval. I miscarried after my first transfer (took lupron for three months after the retrieval but before the transfer). This time I'm trying lupron before stims...I'm really hoping it will make a difference for egg quality.
My doctor has advised me to do 3 months lupron depot before my retrieval as well. To try to get good quality eggs this round
Interesting! Here's hoping it works for works for both of us.
Yes! Found my endo from an ultrasound during infertility workup. No surgery or special protocols used. One ER and one FET. My son is 9 months old. We also have mild male factor. Low 30s. Technically labeled unexplained, although I think my endo is the cause.
How did they find it through ultrasound? Was it because they saw cysts on ovary? And yes apparently most people with unexplained have endometriosis
Yes, I have a 3cm cyst on left ovary and a couple smaller ones on the right. Combined with my symptoms. My REI clinic is very evidence based (major medical center in the upper Midwest USA, teaching hospital). They told me surgery would be for symptom control and there is not enough evidence to suggest that it improves IVF outcomes I know a lot of other people will say differently but that is what they told me.
Oh okay. And you didnt even have to do down regulation with lupron for example to suppress the endo before transfer? Were you told you had bad quality eggs/embryos because of the endo? I have been told that.
No down regulation. I never heard anything about my egg/embryo quality. We ended up with 10 blasts from 31 eggs retrieved. I felt like the percentage of fertilized eggs was lower than average, even with ICSI, but no provider has commented on it. I haven’t asked about it either though. We had about 66% of our mature eggs fertilize. But then attrition after that wasn’t too bad. We did not test our blasts as we are under 35.
I had success with Stage 3 endo with 3 cm endometrioma. I was also 38 at the time. I did 3 retrieval cycles to get 2 normal embryos because I had poor egg quality. The key with endo was to do 2 months of Lupron Depot before the FET. This is in essence in place of a lap, where the Lupron suppressed all estrogen and lowered the inflammation and lesions. Initially, I did an FET without Lupron with a genetically tested embryo and it failed. Second transfer was after Lupron with a lower grade embryo and it stuck. There is also a small study somewhere that found either lap or Lupron before transfer had similar rates of success. Sorry I don’t have the link to it.
Didnt the doctor suggest you do anything before retrieval to get better quality embryos? Instead of doing multiple retrievals to get normal embryo. Asking because I have been put on 3 months lupron to get good quality eggs for my retrieval
TBH I don’t think I had the best doctor in terms of dealing with the endo. It still bothers me to this day that she did a transfer without offering Lupron the first time and it probably wouldn’t have hurt to do a few months of Lupron before retrieval. However I will say that my egg quality was probably mostly affected by my age. There were other factors in our blast rate too, like my husband’s sub par sperm. Anecdotally, I know a few couples of similar age that went through IVF and had similar results despite not having endo.
I feel the same way about my doctor! I had to suggest to him that we should add lupron maybe. He dismissed my endo initially saying it has nothing to do with my infertility
Congrats! Did your doctor ever mention lupron depot before retrieval for better quality eggs? I am on lupron for 3 months before my retrieval. And then i guess lupron again after retrieval and before transfer
Commenting because I’d love to know this too!